The role of cerebrospinal fluid levels of neutrophil gelatinase-associated lipocalin (NGAL) and electroencephalography in the assessment of impaired consciousness in the context of infection

The sepsis syndrome is potentially affecting several organs and systems irrespectively of the primary source of the infection. Alterations of the brain function in sepsis patients may result either from a primary central nervous system (CNS) infection or could be part of the sepsis-associated enceph...

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Published in:Romanian Journal of Internal Medicine
Main Authors: Platanaki Christina, Paraskevas Themistoklis, Delastic Anna-Lisa, Michailides Christos, Kantanis Anastasios, Polychronopoulos Panagiotis, Marangos Markos, Velissaris Dimitrios
Format: Article
Language:English
Published: Sciendo 2023-06-01
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Online Access:https://doi.org/10.2478/rjim-2023-0005
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author Platanaki Christina
Paraskevas Themistoklis
Delastic Anna-Lisa
Michailides Christos
Kantanis Anastasios
Polychronopoulos Panagiotis
Marangos Markos
Velissaris Dimitrios
author_facet Platanaki Christina
Paraskevas Themistoklis
Delastic Anna-Lisa
Michailides Christos
Kantanis Anastasios
Polychronopoulos Panagiotis
Marangos Markos
Velissaris Dimitrios
author_sort Platanaki Christina
collection DOAJ
container_title Romanian Journal of Internal Medicine
description The sepsis syndrome is potentially affecting several organs and systems irrespectively of the primary source of the infection. Alterations of the brain function in sepsis patients may result either from a primary central nervous system (CNS) infection or could be part of the sepsis-associated encephalopathy (SAE), a common complication of sepsis, characterized by a diffuse dysfunction of the brain due to an infection elsewhere in the body without overt CNS infection. Aim of the study was to evaluate the usefulness of electroencephalography and the biomarker neutrophil gelatinase-associated lipocalin (NGAL) when measured in the cerebrospinal fluid (CSF) in the management of these patients.
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spelling doaj-art-5afcf27e5ff24ef79d3e354ceb5afcf72025-08-19T21:26:18ZengSciendoRomanian Journal of Internal Medicine2501-062X2023-06-0161211211510.2478/rjim-2023-0005The role of cerebrospinal fluid levels of neutrophil gelatinase-associated lipocalin (NGAL) and electroencephalography in the assessment of impaired consciousness in the context of infectionPlatanaki Christina0Paraskevas Themistoklis1Delastic Anna-Lisa2Michailides Christos3Kantanis Anastasios4Polychronopoulos Panagiotis5Marangos Markos6Velissaris Dimitrios71Department of Internal Medicine, University General Hospital of Patras, Greece1Department of Internal Medicine, University General Hospital of Patras, Greece2Department of Internal Medicine, Section of Infectious Diseases, University General Hospital of Patras, Greece1Department of Internal Medicine, University General Hospital of Patras, Greece3Department of General Practice and Family Medicine, General University Hospital of Patras, Patras, Greece4Department of Neurology, University General Hospital of Patras, Greece1Department of Internal Medicine, University General Hospital of Patras, Greece1Department of Internal Medicine, University General Hospital of Patras, GreeceThe sepsis syndrome is potentially affecting several organs and systems irrespectively of the primary source of the infection. Alterations of the brain function in sepsis patients may result either from a primary central nervous system (CNS) infection or could be part of the sepsis-associated encephalopathy (SAE), a common complication of sepsis, characterized by a diffuse dysfunction of the brain due to an infection elsewhere in the body without overt CNS infection. Aim of the study was to evaluate the usefulness of electroencephalography and the biomarker neutrophil gelatinase-associated lipocalin (NGAL) when measured in the cerebrospinal fluid (CSF) in the management of these patients.https://doi.org/10.2478/rjim-2023-0005biomarkerelectroencephalographysepsis syndromeneutrophil gelatinase-associated lipocalinemergency departmentdiagnosis
spellingShingle Platanaki Christina
Paraskevas Themistoklis
Delastic Anna-Lisa
Michailides Christos
Kantanis Anastasios
Polychronopoulos Panagiotis
Marangos Markos
Velissaris Dimitrios
The role of cerebrospinal fluid levels of neutrophil gelatinase-associated lipocalin (NGAL) and electroencephalography in the assessment of impaired consciousness in the context of infection
biomarker
electroencephalography
sepsis syndrome
neutrophil gelatinase-associated lipocalin
emergency department
diagnosis
title The role of cerebrospinal fluid levels of neutrophil gelatinase-associated lipocalin (NGAL) and electroencephalography in the assessment of impaired consciousness in the context of infection
title_full The role of cerebrospinal fluid levels of neutrophil gelatinase-associated lipocalin (NGAL) and electroencephalography in the assessment of impaired consciousness in the context of infection
title_fullStr The role of cerebrospinal fluid levels of neutrophil gelatinase-associated lipocalin (NGAL) and electroencephalography in the assessment of impaired consciousness in the context of infection
title_full_unstemmed The role of cerebrospinal fluid levels of neutrophil gelatinase-associated lipocalin (NGAL) and electroencephalography in the assessment of impaired consciousness in the context of infection
title_short The role of cerebrospinal fluid levels of neutrophil gelatinase-associated lipocalin (NGAL) and electroencephalography in the assessment of impaired consciousness in the context of infection
title_sort role of cerebrospinal fluid levels of neutrophil gelatinase associated lipocalin ngal and electroencephalography in the assessment of impaired consciousness in the context of infection
topic biomarker
electroencephalography
sepsis syndrome
neutrophil gelatinase-associated lipocalin
emergency department
diagnosis
url https://doi.org/10.2478/rjim-2023-0005
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