Tricyclic antidepressant amitriptyline indirectly increases the proliferation of adult dentate gyrus-derived neural precursors: an involvement of astrocytes.

Antidepressants increase the proliferation of neural precursors in adult dentate gyrus (DG), which is considered to be involved in the therapeutic action of antidepressants. However, the mechanism underlying it remains unclear. By using cultured adult rat DG-derived neural precursors (ADP), we have...

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Bibliographic Details
Published in:	PLoS ONE
Main Authors:	Shuken Boku, Kazue Hisaoka-Nakashima, Shin Nakagawa, Akiko Kato, Naoto Kajitani, Takeshi Inoue, Ichiro Kusumi, Minoru Takebayashi
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2013-01-01
Online Access:	http://europepmc.org/articles/PMC3832593?pdf=render

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