Anxiety in Autism Spectrum Disorder: Clinical Characteristics and the Role of the Family

Background: Anxiety Disorder (AD) is among the most common psychiatric comorbidity in children and adolescents with Autism Spectrum Disorder (ASD). Likewise, parental psychological distress (PPD) was linked to anxiety symptoms in children and adolescents with ASD. The aim of this study was to charac...

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Published in:Brain Sciences
Main Authors: Silvia Guerrera, Maria Pontillo, Maria Cristina Tata, Cristina Di Vincenzo, Domenica Bellantoni, Eleonora Napoli, Giovanni Valeri, Stefano Vicari
Format: Article
Language:English
Published: MDPI AG 2022-11-01
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Online Access:https://www.mdpi.com/2076-3425/12/12/1597
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author Silvia Guerrera
Maria Pontillo
Maria Cristina Tata
Cristina Di Vincenzo
Domenica Bellantoni
Eleonora Napoli
Giovanni Valeri
Stefano Vicari
author_facet Silvia Guerrera
Maria Pontillo
Maria Cristina Tata
Cristina Di Vincenzo
Domenica Bellantoni
Eleonora Napoli
Giovanni Valeri
Stefano Vicari
author_sort Silvia Guerrera
collection DOAJ
container_title Brain Sciences
description Background: Anxiety Disorder (AD) is among the most common psychiatric comorbidity in children and adolescents with Autism Spectrum Disorder (ASD). Likewise, parental psychological distress (PPD) was linked to anxiety symptoms in children and adolescents with ASD. The aim of this study was to characterise, in a sample of children and adolescents with ASD, anxiety symptoms, the functional impairment associated and the presence of PPD. Methods: Participants were divided into three groups based on their diagnosis: children and adolescents with a diagnosis of ASD + AD, others with a diagnosis of AD but without a diagnosis of ASD, and others with a diagnosis of ASD but without a diagnosis of AD. Results: Group ASD + AD showed lower global functioning than Group ASD and Group AD. Generalised Anxiety Disorder, Separation Anxiety Disorder and Specific Phobias were more frequent in Group ASD + AD. Our findings also showed higher depressive symptoms in Group ASD + AD, both in the child and parent reports. Finally, parents of the Group ASD + AD revealed higher levels of PPD. Conclusions: Our findings suggest that early assessment of AD with functional impairment associated with the role of PPD could define individualised treatments and consequently mean a better prognosis in children and adolescents with ASD and AD.
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spelling doaj-art-5c44fa69011d47d882ea46dd35fd235f2025-08-19T23:50:53ZengMDPI AGBrain Sciences2076-34252022-11-011212159710.3390/brainsci12121597Anxiety in Autism Spectrum Disorder: Clinical Characteristics and the Role of the FamilySilvia Guerrera0Maria Pontillo1Maria Cristina Tata2Cristina Di Vincenzo3Domenica Bellantoni4Eleonora Napoli5Giovanni Valeri6Stefano Vicari7Child and Adolescence Neuropsychiatry Unit, Department of Neuroscience, Bambino Gesù Children’s Hospital, IRCCS, Viale Ferdinando Baldelli, 41, 00146 Rome, ItalyChild and Adolescence Neuropsychiatry Unit, Department of Neuroscience, Bambino Gesù Children’s Hospital, IRCCS, Viale Ferdinando Baldelli, 41, 00146 Rome, ItalyChild and Adolescence Neuropsychiatry Unit, Department of Neuroscience, Bambino Gesù Children’s Hospital, IRCCS, Viale Ferdinando Baldelli, 41, 00146 Rome, ItalyChild and Adolescence Neuropsychiatry Unit, Department of Neuroscience, Bambino Gesù Children’s Hospital, IRCCS, Viale Ferdinando Baldelli, 41, 00146 Rome, ItalyChild and Adolescence Neuropsychiatry Unit, Department of Neuroscience, Bambino Gesù Children’s Hospital, IRCCS, Viale Ferdinando Baldelli, 41, 00146 Rome, ItalyNeurorehabilitation Unit, Bambino Gesù Children’s Hospital, IRCCS, 00165 Rome, ItalyChild and Adolescence Neuropsychiatry Unit, Department of Neuroscience, Bambino Gesù Children’s Hospital, IRCCS, Viale Ferdinando Baldelli, 41, 00146 Rome, ItalyChild and Adolescence Neuropsychiatry Unit, Department of Neuroscience, Bambino Gesù Children’s Hospital, IRCCS, Viale Ferdinando Baldelli, 41, 00146 Rome, ItalyBackground: Anxiety Disorder (AD) is among the most common psychiatric comorbidity in children and adolescents with Autism Spectrum Disorder (ASD). Likewise, parental psychological distress (PPD) was linked to anxiety symptoms in children and adolescents with ASD. The aim of this study was to characterise, in a sample of children and adolescents with ASD, anxiety symptoms, the functional impairment associated and the presence of PPD. Methods: Participants were divided into three groups based on their diagnosis: children and adolescents with a diagnosis of ASD + AD, others with a diagnosis of AD but without a diagnosis of ASD, and others with a diagnosis of ASD but without a diagnosis of AD. Results: Group ASD + AD showed lower global functioning than Group ASD and Group AD. Generalised Anxiety Disorder, Separation Anxiety Disorder and Specific Phobias were more frequent in Group ASD + AD. Our findings also showed higher depressive symptoms in Group ASD + AD, both in the child and parent reports. Finally, parents of the Group ASD + AD revealed higher levels of PPD. Conclusions: Our findings suggest that early assessment of AD with functional impairment associated with the role of PPD could define individualised treatments and consequently mean a better prognosis in children and adolescents with ASD and AD.https://www.mdpi.com/2076-3425/12/12/1597Autism Spectrum Disorderanxiety symptomspsychiatric comorbiditiesparental psychological distresschildrenadolescents
spellingShingle Silvia Guerrera
Maria Pontillo
Maria Cristina Tata
Cristina Di Vincenzo
Domenica Bellantoni
Eleonora Napoli
Giovanni Valeri
Stefano Vicari
Anxiety in Autism Spectrum Disorder: Clinical Characteristics and the Role of the Family
Autism Spectrum Disorder
anxiety symptoms
psychiatric comorbidities
parental psychological distress
children
adolescents
title Anxiety in Autism Spectrum Disorder: Clinical Characteristics and the Role of the Family
title_full Anxiety in Autism Spectrum Disorder: Clinical Characteristics and the Role of the Family
title_fullStr Anxiety in Autism Spectrum Disorder: Clinical Characteristics and the Role of the Family
title_full_unstemmed Anxiety in Autism Spectrum Disorder: Clinical Characteristics and the Role of the Family
title_short Anxiety in Autism Spectrum Disorder: Clinical Characteristics and the Role of the Family
title_sort anxiety in autism spectrum disorder clinical characteristics and the role of the family
topic Autism Spectrum Disorder
anxiety symptoms
psychiatric comorbidities
parental psychological distress
children
adolescents
url https://www.mdpi.com/2076-3425/12/12/1597
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