Investigation of in situ gelling alginate formulations as a sustained release vehicle for co-precipitates of dextromethrophan and Eudragit S 100

Alginate vehicles are capable of forming a gel matrix in situ when they come into contact with gastric medium in the presence of calcium ions. However, the gel structure is pH dependent and can break after gastric emptying, leading to dose dumping. The aim of this work was to develop modified in sit...

书目详细资料
发表在:	Acta Pharmaceutica
Main Authors:	Maghraby Gamal Mohamed El, Elzayat Ehab Mostafa, Alanazi Fars Kaed
格式:	文件
语言:	英语
出版:	Sciendo 2014-03-01
主题:	dextromethorphan solid dispersion in situ gelling alginate gels
在线阅读:	http://www.degruyter.com/view/j/acph.2014.64.issue-1/acph-2014-0002/acph-2014-0002.xml?format=INT

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