Multifunctional nanocomposites utilizing ruthenium (II) complex/manganese (IV) dioxide nanoparticle for synergistic reinforcing radioimmunotherapy

Abstract Radiotherapy (RT) stands as a frontline treatment modality in clinical breast oncology, yet challenges like ROS reduction, high toxicity, non-selectivity, and hypoxia hinder efficacy. Additionally, RT administered at different doses can induce varying degrees of radioimmunotherapy. High dos...

Full description

Bibliographic Details

Published in:	Journal of Nanobiotechnology
Main Authors:	Jian Peng, Dong-Ling Quan, Guang Yang, Lin-Tao Wei, Zhuan Yang, Zhi-Ying Dong, Yi-Ming Zou, Ying-Ke Hou, Jin-Xiang Chen, Lin Lv, Bin Sun
Format:	Article
Language:	English
Published:	BMC 2024-11-01
Subjects:	Radiosensitizer Radioimmunotherapy Ruthenium complex MnO2 cGAS-STING
Online Access:	https://doi.org/10.1186/s12951-024-03013-2