Efficacy of L-Arginine for Preventing Preeclampsia and Improving Maternal and Neonatal Outcomes in High-Risk Pregnancies: A Systematic Review and Meta-Analysis

Preeclampsia (PE) remains a significant cause of maternal and neonatal morbidity and mortality, particularly in high-riskpregnancies. The present study aims to assess the efficacy of L-arginine supplementation in preventing PE and improvingmaternal and neonatal outcomes in high-risk pregnancies. We...

Full description

Bibliographic Details
Published in:	International Journal of Fertility and Sterility
Main Authors:	Fatemeh Naderipour, Fariba Keshavarzi, Hosna Mirfakhraee, Parisa Dini, Niousha Jamshidnezhad, Nastaran Abolghasem, Foroogh Sabzghabaei, Fatemeh Shariatinia
Format:	Article
Language:	English
Published:	Royan Institute (ACECR), Tehran 2024-10-01
Subjects:	high-risk pregnancies l-arginine nutritional supplements preeclampsia
Online Access:	https://www.ijfs.ir/article_711909_511a707f0e39e23d0d9e3a2427a07f95.pdf

Similar Items

L-arginine improves uterine spiral arterial wall thickness in mouse models of preeclampsia
by: Soetrisno Soetrisno, et al.
Published: (2017-08-01)

Potency of Oral L-Arginine Suplementation Based on Chitosan-Coated Gold Nanoparticles (c-AuNPs) as Preeclampsia Prevention in Pregnant Women
by: Fara Syafira, et al.
Published: (2022-09-01)

Hypoxia Inducible Factor-1-Alpha Expression on Preeclampsia Mice Model With L-Arginine Administration
by: Nutria Widya Purna Anggraini, et al.
Published: (2021-09-01)

L-Arginine, Suatu Peluang Neuroproteksi terhadap Pasien Preeklampsia yang mendapat Problem Neurologis
by: Niken Asri Utami, et al.
Published: (2019-06-01)

L-arginine supplementation minimizes aging-induced changes in the sperm chromatin of roosters
by: Luciana Beatriz Tiago Oliveira, et al.
Published: (2023-08-01)

THE ROLE OF MAGNESIUM SUPPLEMENTS ON HYPERTENSION IN PREGNANCY AND PREECLAMPSIA
by: Raissa Nurwany, et al.
Published: (2024-01-01)

Maternal Periodontitis, Preeclampsia and Adverse Pregnancy Outcomes
by: Pourandokht Afshari, et al.
Published: (2013-07-01)

Maternal and neonatal outcome among women with early-onset preeclampsia and late-onset preeclampsia
by: Luthfi Rahman, et al.
Published: (2024-12-01)

Exploration of Microencapsulation of Arginine in Carnauba Wax (<i>Copernicia prunifera</i>) and Its Dietary Effect on the Quality of Beef
by: German Contreras-Lopez, et al.
Published: (2024-06-01)

Is postpartum preeclampsia a continuation of intrapartum preeclampsia? Maternal risk factors in intrapartum vs. postpartum preeclampsia: a retrospective cohort study
by: Hila Shalev-Ram, et al.
Published: (2025-10-01)

Comparison of Diagnostic Values of Maternal Arginine Concentration for Different Pregnancy Complications: A Systematic Review and Meta-Analysis
by: Lianbin Xu, et al.
Published: (2022-01-01)

Maternal serum perlecan levels in women with preeclampsia
by: Murat Akbas, et al.
Published: (2020-01-01)

The Effect of l-Arginine Supplementation on Indices of Delayed-Onset Muscle Soreness after One-Session Exhaustive Aerobic Training in Inactive Men
by: Mohammad Azizi, et al.
Published: (2019-07-01)

Relation of multimineral-vitamin D supplementation and the risk of preeclampsia
by: Mohamed A El-Naggar, et al.
Published: (2022-01-01)

The placental vascular endothelial growth factor polymorphisms and preeclampsia/preeclampsia severity
by: Farshid Keshavarzi, et al.
Published: (2017-10-01)

Effect of early vitamin D supplementation on the incidence of preeclampsia in primigravid women: a randomised clinical trial in Eastern Democratic Republic of the Congo
by: Richard Kabuseba Kabuyanga, et al.
Published: (2024-02-01)

Maternal and Neonatal Outcomes in Women with Preeclampsia
by: Mandana Saadat, et al.
Published: (2007-09-01)

Dietary Supplementation With Leucine or in Combination With Arginine Decreases Body Fat Weight and Alters Gut Microbiota Composition in Finishing Pigs
by: Chengjun Hu, et al.
Published: (2019-08-01)

L-Arginine and Cardioactive Arginine Derivatives as Substrates and Inhibitors of Human and Mouse NaCT/Nact
by: Daniela B. Surrer, et al.
Published: (2022-03-01)

Maternal serum autotaxin levels in early- and late-onset preeclampsia
by: Hakan Erenel, et al.
Published: (2017-10-01)

The importance of proteinuria in preeclampsia and its predictive role in maternal and neonatal outcomes
by: Atakan Tanacan, et al.
Published: (2019-04-01)

Dysregulation of arginine methylation in tumorigenesis
by: Xiao Li, et al.
Published: (2024-06-01)

Neonatal Thrombocytopenia as a Consequence of Maternal Preeclampsia
by: Ram R. Kalagiri, et al.
Published: (2016-03-01)

Maternal periodontal disease and preeclampsia in Jaipur population
by: Girija Jaiman, et al.
Published: (2018-01-01)

Effects of apelin on neonatal brain neurogenesis in L-NAME-induced maternal preeclampsia
by: Canberk Tomruk, et al.
Published: (2024-08-01)

Acute effects of combined supplementation of L-arginine and citrulline malate on aerobic, anaerobic, and CrossFit exercise performance
by: Saranya Selvaraj, et al.
Published: (2025-09-01)

Arginine and Endothelial Function
by: Jessica Gambardella, et al.
Published: (2020-08-01)

The Relationship Between Proteinuria in Severe Preeclampsia and Maternal and Fetal Outcomes
by: Huriye Ayşe Parlakgümüş, et al.
Published: (2012-04-01)

Effects of calcium supplementation on the prevention of preeclampsia: an umbrella review of systematic reviews and meta-analyses
by: Henok Kumsa, et al.
Published: (2025-03-01)

L-arginine Supplementation in Endurance Athletes: A Systematic Review of Recovery Mechanisms and Performance Enhancement
by: Łukasz Karoń, et al.
Published: (2024-11-01)

Sleep Disturbances in Early Pregnancy and the Risk of Preeclampsia: Qazvin Maternal and Neonatal Metabolic Outcomes Study (QMNMS)
by: Sima Hashemipour, et al.
Published: (2025-07-01)

Pregestational maternal risk factors for preterm and term preeclampsia: A population‐based cohort study
by: Anne Kvie Sande, et al.
Published: (2023-11-01)

Entamoeba histolytica: protein arginine transferase 1a methylates arginine residues and potentially modify the H4 histone
by: Jessica Borbolla-Vázquez, et al.
Published: (2015-04-01)

Influence of Maternal Preeclampsia on Neurodevelopmental Outcomes of Preterm Infants
by: Halil Degirmencioglu, et al.
Published: (2018-08-01)

The role of maternal free testosteron and dehydroepiandrosterone sulfate in preeclampsia
by: Cagdas Colluoglu, et al.
Published: (2016-03-01)

The Evaluation of L-arginine Prophylaxis and Treatment on Preventing Nephrotoxicity Cisplatin-Induced in Rat: Role of Gender Difference
by: Moazzameh Meimandinia, et al.
Published: (2015-08-01)

Evaluation of maternal systemic inflammatory response in preeclampsia
by: Dan Mihu, et al.
Published: (2015-04-01)

Asociación entre hiperhomocisteinemia y preeclampsia Association between hyperhomocysteinemia and preeclampsia
by: Jorge Mario Gómez Jiménez, et al.
Published: (2002-03-01)

Amperometric Biosensors for L-Arginine Determination Based on L-Arginine Oxidase and Peroxidase-Like Nanozymes
by: Nataliya Stasyuk, et al.
Published: (2021-07-01)

The possible role of maternal and placental vitamin D receptor polymorphisms and haplotypes in pathogenesis of preeclampsia
by: Farzaneh Farajian-Mashhadi, et al.
Published: (2020-02-01)