Amyloid PET Radiopharmaceuticals and Imaging for Clinical and Research Applications in Thailand
In the past two decades, the research community has focused on defining reliable molecular biomarkers for the early diagnosis of Alzheimer's disease (AD). Several PET radiopharmaceuticals have been developed and gained regulatory approval for the non-invasive detection of Aβ amyloid deposits i...
| Published in: | Siriraj Medical Journal |
|---|---|
| Main Authors: | , , |
| Format: | Article |
| Language: | English |
| Published: |
Faculty of Medicine Siriraj Hospital
2023-09-01
|
| Subjects: | |
| Online Access: | https://he02.tci-thaijo.org/index.php/sirirajmedj/article/view/263161 |
| _version_ | 1850271107319332864 |
|---|---|
| author | Tossaporn Siriprapa Tanyaluck Thientunyakit Juri Gelovani |
| author_facet | Tossaporn Siriprapa Tanyaluck Thientunyakit Juri Gelovani |
| author_sort | Tossaporn Siriprapa |
| collection | DOAJ |
| container_title | Siriraj Medical Journal |
| description |
In the past two decades, the research community has focused on defining reliable molecular biomarkers for the early diagnosis of Alzheimer's disease (AD). Several PET radiopharmaceuticals have been developed and gained regulatory approval for the non-invasive detection of Aβ amyloid deposits in the brain. Nowadays, there are several PET imaging tracers available in Thailand for amyloid imaging including [11C]PiB, [18F]Florbetapir, and [18F]Florbetaben. This review provides a summary of commonly used amyloid PET radiopharmaceuticals, focusing on the available radiopharmaceuticals in Thailand and the experiences of using amyloid PET radiopharmaceuticals and imaging for clinical and research applications at Siriraj Hospital.
|
| format | Article |
| id | doaj-art-60da63629bb24934a3feb0fa5c19ae83 |
| institution | Directory of Open Access Journals |
| issn | 2228-8082 |
| language | English |
| publishDate | 2023-09-01 |
| publisher | Faculty of Medicine Siriraj Hospital |
| record_format | Article |
| spelling | doaj-art-60da63629bb24934a3feb0fa5c19ae832025-08-19T23:42:45ZengFaculty of Medicine Siriraj HospitalSiriraj Medical Journal2228-80822023-09-01759Amyloid PET Radiopharmaceuticals and Imaging for Clinical and Research Applications in ThailandTossaporn Siriprapa0Tanyaluck Thientunyakit1Juri Gelovani2Division of Nuclear Medicine, Department of Radiology, Faculty of Medicine Siriraj Hospital, Mahidol University, BangkokDivision of Nuclear Medicine, Department of Radiology, Faculty of Medicine Siriraj Hospital, Mahidol University, BangkokDepartment of Biomedical Engineering, College of Engineering and School of Medicine, Wayne State University, Detroit, USA / College of Medicine and Health Sciences, United Arab Emirates University, Al Ain, United Arab Emirates In the past two decades, the research community has focused on defining reliable molecular biomarkers for the early diagnosis of Alzheimer's disease (AD). Several PET radiopharmaceuticals have been developed and gained regulatory approval for the non-invasive detection of Aβ amyloid deposits in the brain. Nowadays, there are several PET imaging tracers available in Thailand for amyloid imaging including [11C]PiB, [18F]Florbetapir, and [18F]Florbetaben. This review provides a summary of commonly used amyloid PET radiopharmaceuticals, focusing on the available radiopharmaceuticals in Thailand and the experiences of using amyloid PET radiopharmaceuticals and imaging for clinical and research applications at Siriraj Hospital. https://he02.tci-thaijo.org/index.php/sirirajmedj/article/view/263161Amyloid PET radiopharmaceuticalsAlzheimer’s diseaseAmyloid beta plaque (Aβ)Molecular imagingDementiaamyloid deposition |
| spellingShingle | Tossaporn Siriprapa Tanyaluck Thientunyakit Juri Gelovani Amyloid PET Radiopharmaceuticals and Imaging for Clinical and Research Applications in Thailand Amyloid PET radiopharmaceuticals Alzheimer’s disease Amyloid beta plaque (Aβ) Molecular imaging Dementia amyloid deposition |
| title | Amyloid PET Radiopharmaceuticals and Imaging for Clinical and Research Applications in Thailand |
| title_full | Amyloid PET Radiopharmaceuticals and Imaging for Clinical and Research Applications in Thailand |
| title_fullStr | Amyloid PET Radiopharmaceuticals and Imaging for Clinical and Research Applications in Thailand |
| title_full_unstemmed | Amyloid PET Radiopharmaceuticals and Imaging for Clinical and Research Applications in Thailand |
| title_short | Amyloid PET Radiopharmaceuticals and Imaging for Clinical and Research Applications in Thailand |
| title_sort | amyloid pet radiopharmaceuticals and imaging for clinical and research applications in thailand |
| topic | Amyloid PET radiopharmaceuticals Alzheimer’s disease Amyloid beta plaque (Aβ) Molecular imaging Dementia amyloid deposition |
| url | https://he02.tci-thaijo.org/index.php/sirirajmedj/article/view/263161 |
| work_keys_str_mv | AT tossapornsiriprapa amyloidpetradiopharmaceuticalsandimagingforclinicalandresearchapplicationsinthailand AT tanyaluckthientunyakit amyloidpetradiopharmaceuticalsandimagingforclinicalandresearchapplicationsinthailand AT jurigelovani amyloidpetradiopharmaceuticalsandimagingforclinicalandresearchapplicationsinthailand |
