Amyloid PET Radiopharmaceuticals and Imaging for Clinical and Research Applications in Thailand

In the past two decades, the research community has focused on defining reliable molecular biomarkers for the early diagnosis of Alzheimer's disease (AD). Several PET radiopharmaceuticals have been developed and gained regulatory approval for the non-invasive detection of Aβ amyloid deposits i...

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Published in:Siriraj Medical Journal
Main Authors: Tossaporn Siriprapa, Tanyaluck Thientunyakit, Juri Gelovani
Format: Article
Language:English
Published: Faculty of Medicine Siriraj Hospital 2023-09-01
Subjects:
Online Access:https://he02.tci-thaijo.org/index.php/sirirajmedj/article/view/263161
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author Tossaporn Siriprapa
Tanyaluck Thientunyakit
Juri Gelovani
author_facet Tossaporn Siriprapa
Tanyaluck Thientunyakit
Juri Gelovani
author_sort Tossaporn Siriprapa
collection DOAJ
container_title Siriraj Medical Journal
description In the past two decades, the research community has focused on defining reliable molecular biomarkers for the early diagnosis of Alzheimer's disease (AD). Several PET radiopharmaceuticals have been developed and gained regulatory approval for the non-invasive detection of Aβ amyloid deposits in the brain. Nowadays, there are several PET imaging tracers available in Thailand for amyloid imaging including [11C]PiB, [18F]Florbetapir, and [18F]Florbetaben. This review provides a summary of commonly used amyloid PET radiopharmaceuticals, focusing on the available radiopharmaceuticals in Thailand and the experiences of using amyloid PET radiopharmaceuticals and imaging for clinical and research applications at Siriraj Hospital.  
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spelling doaj-art-60da63629bb24934a3feb0fa5c19ae832025-08-19T23:42:45ZengFaculty of Medicine Siriraj HospitalSiriraj Medical Journal2228-80822023-09-01759Amyloid PET Radiopharmaceuticals and Imaging for Clinical and Research Applications in ThailandTossaporn Siriprapa0Tanyaluck Thientunyakit1Juri Gelovani2Division of Nuclear Medicine, Department of Radiology, Faculty of Medicine Siriraj Hospital, Mahidol University, BangkokDivision of Nuclear Medicine, Department of Radiology, Faculty of Medicine Siriraj Hospital, Mahidol University, BangkokDepartment of Biomedical Engineering, College of Engineering and School of Medicine, Wayne State University, Detroit, USA / College of Medicine and Health Sciences, United Arab Emirates University, Al Ain, United Arab Emirates In the past two decades, the research community has focused on defining reliable molecular biomarkers for the early diagnosis of Alzheimer's disease (AD). Several PET radiopharmaceuticals have been developed and gained regulatory approval for the non-invasive detection of Aβ amyloid deposits in the brain. Nowadays, there are several PET imaging tracers available in Thailand for amyloid imaging including [11C]PiB, [18F]Florbetapir, and [18F]Florbetaben. This review provides a summary of commonly used amyloid PET radiopharmaceuticals, focusing on the available radiopharmaceuticals in Thailand and the experiences of using amyloid PET radiopharmaceuticals and imaging for clinical and research applications at Siriraj Hospital.   https://he02.tci-thaijo.org/index.php/sirirajmedj/article/view/263161Amyloid PET radiopharmaceuticalsAlzheimer’s diseaseAmyloid beta plaque (Aβ)Molecular imagingDementiaamyloid deposition
spellingShingle Tossaporn Siriprapa
Tanyaluck Thientunyakit
Juri Gelovani
Amyloid PET Radiopharmaceuticals and Imaging for Clinical and Research Applications in Thailand
Amyloid PET radiopharmaceuticals
Alzheimer’s disease
Amyloid beta plaque (Aβ)
Molecular imaging
Dementia
amyloid deposition
title Amyloid PET Radiopharmaceuticals and Imaging for Clinical and Research Applications in Thailand
title_full Amyloid PET Radiopharmaceuticals and Imaging for Clinical and Research Applications in Thailand
title_fullStr Amyloid PET Radiopharmaceuticals and Imaging for Clinical and Research Applications in Thailand
title_full_unstemmed Amyloid PET Radiopharmaceuticals and Imaging for Clinical and Research Applications in Thailand
title_short Amyloid PET Radiopharmaceuticals and Imaging for Clinical and Research Applications in Thailand
title_sort amyloid pet radiopharmaceuticals and imaging for clinical and research applications in thailand
topic Amyloid PET radiopharmaceuticals
Alzheimer’s disease
Amyloid beta plaque (Aβ)
Molecular imaging
Dementia
amyloid deposition
url https://he02.tci-thaijo.org/index.php/sirirajmedj/article/view/263161
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AT jurigelovani amyloidpetradiopharmaceuticalsandimagingforclinicalandresearchapplicationsinthailand