Design, Synthesis, Evaluation and Molecular Dynamics Simulation of Dengue Virus NS5-RdRp Inhibitors

Dengue virus (DENV) is a major mosquito-borne human pathogen in tropical countries; however, there are currently no targeted antiviral treatments for DENV infection. Compounds <b>27</b> and <b>29</b> have been reported to be allosteric inhibitors of DENV RdRp with potent inhi...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:	Pharmaceuticals
المؤلفون الرئيسيون:	Keli Zong, Wei Li, Yijie Xu, Xu Zhao, Ruiyuan Cao, Hong Yan, Xingzhou Li
التنسيق:	مقال
اللغة:	الإنجليزية
منشور في:	MDPI AG 2023-11-01
الموضوعات:	dengue virus antiviral compounds NS5-RdRp inhibitors molecular docking
الوصول للمادة أونلاين:	https://www.mdpi.com/1424-8247/16/11/1625

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