THE PROBLEM OF HEART TRANSPLANT REJECTION AND WAYS OF OPTIMIZING THE ASSESSMENT OF ENDOMYOCARDIAL BIOPSY RESULTS

The following article describes tactics of recipient management when a rejection episode of a heart transplant is being suspected. We have discovered some new figures to assess biopsy samples through computerised morphometric study, which can both improve and clarify biopsy results. CD3+ (T-cells) a...

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Bibliographic Details
Published in:Клиническая практика
Main Authors: T V Stavenchuk, E D Kosmachova, I A Shelestova, A A Slavinsky, E A Terman, A A Verevkin, L A Medvedeva, K O Barbuhatty, Z G Tatarintseva, V A Porchanov
Format: Article
Language:English
Published: Eco-vector 2017-09-01
Subjects:
computerised morphometric study
endomyocardial biopsy
heart transplant rejection
Online Access:https://journals.eco-vector.com/clinpractice/article/viewFile/8046/6469
Description
Summary:The following article describes tactics of recipient management when a rejection episode of a heart transplant is being suspected. We have discovered some new figures to assess biopsy samples through computerised morphometric study, which can both improve and clarify biopsy results. CD3+ (T-cells) and CD 68+ (macrophages) figures make it possible to determine the extent of transplant rejection in accordance with the International Society for Heart and Lung Transplantation diagnostic criteria (sensitivity 91%, specificity 91%).
ISSN:2220-3095
2618-8627

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