Aqueous humor cytokine levels in patients with subretinal fibrosis in neovascular age-related macular degeneration

Abstract Purpose To investigate aqueous humor cytokine levels in neovascular age-related macular degeneration (nAMD) patients with subretinal fibrosis and to explore the relationship between cytokine levels and disease severity. Methods The aqueous humor samples were collected from 16 eyes with subr...

Full description

Bibliographic Details
Published in:	BMC Ophthalmology
Main Authors:	Ying Cao, Meijia Dang, Zhen Tian, Tiantian Zhang, Lihua Hou, Min Wang, Shuhui Xing, Yingni Huang, Jing Li
Format:	Article
Language:	English
Published:	BMC 2024-08-01
Subjects:	Aqueous humor Cytokine Neovascular age-related macular degeneration Subretinal fibrosis
Online Access:	https://doi.org/10.1186/s12886-024-03614-3

Similar Items

Analyses of the effects of persistent subretinal fluid on visual/anatomic outcomes according to the type of macular neovascularization during the relaxed treat-and-extend protocol in age-related macular degeneration patients
by: Kyung Tae Kim, et al.
Published: (2021-08-01)

Efficacy of a single injection of brolucizumab in neovascular age-related macular degeneration on visual acuity and micromorphometry
by: Shrinivas Joshi, et al.
Published: (2023-01-01)

Potential of autophagy in subretinal fibrosis in neovascular age-related macular degeneration
by: Janusz Blasiak, et al.
Published: (2025-04-01)

Exploring the role of granzyme B in subretinal fibrosis of age-related macular degeneration
by: Karanvir Gill, et al.
Published: (2024-07-01)

Subretinal hyperreflective material morphology in neovascular age-related macular degeneration: A case control study
by: Divya Alex, et al.
Published: (2021-01-01)

Iatrogenic choroidal neovascularization associated with subretinal gene therapy surgery
by: Kenneth W. Price, et al.
Published: (2022-09-01)

Analysis of factors affecting prognosis of the visual acuity and baseline risk factors for subretinal fibrosis in neovascular age-related macular degeneration patients
by: Shihan Liu, et al.
Published: (2024-11-01)

Untargeted Metabolomic Study of Patients with Wet Age-Related Macular Degeneration in Aqueous Humor
by: Wei Q, et al.
Published: (2024-09-01)

Subretinal fibrosis secondary to neovascular age-related macular degeneration: mechanisms and potential therapeutic targets
by: Jingxiang Zhang, et al.
Published: (2025-02-01)

Determination of Vascular Endothelial Growth Factor-B Concentrations in Aqueous Humor and Plasma of Neovascular Age-Related Macular Degeneration and Polypoidal Choroidal Vasculopathy Patients Before and After Anti-VEGF Therapy
by: Huiying Zhou, et al.
Published: (2022-12-01)

Cytokine and Chemokine Profile Changes in Patients with Neovascular Age-Related Macular Degeneration After Intravitreal Ranibizumab Injection for Choroidal Neovascularization
by: Sun T, et al.
Published: (2021-06-01)

Wnt5a/β-catenin-mediated epithelial-mesenchymal transition: a key driver of subretinal fibrosis in neovascular age-related macular degeneration
by: Dandan Liu, et al.
Published: (2024-03-01)

Involvement of <i>Lgals3</i>/Galectin-3 in Choroidal Neovascularization and Subretinal Fibrosis Formation
by: Di Wu, et al.
Published: (2024-11-01)

Deep Learning in Neovascular Age-Related Macular Degeneration
by: Enrico Borrelli, et al.
Published: (2024-06-01)

Hyperreflective material in patients with non-neovascular pachychoroid disease
by: Maiko Maruyama-Inoue, et al.
Published: (2023-06-01)

Photodynamic therapy for neovascular age-related macular degeneration
by: Richard P.L. Wormald, MA, MB, BCh, MSc, FRCS, FRCOphth, et al.
Published: (2005-06-01)

Clinical Evaluation of the Effectiveness of Neovascular Age-related Macular Degeneration Combined Treatment
by: L. A. Golota, et al.
Published: (2025-03-01)

Outcomes and predictive factors for fluid resolution following three loading injections of faricimab for treatment-naïve neovascular age-related macular degeneration
by: Hee Yong Han, et al.
Published: (2025-01-01)

Evaluation of the long-term outcomes of surgery of submacular hemorrhage in patients with exudative age-related macular degeneration
by: V.A. Rudenko, et al.
Published: (2023-03-01)

Influence of subretinal drusenoid deposit on retinal sensitivity in age-related macular degeneration
by: Soo Hyun Lim, et al.
Published: (2025-10-01)

Early detection of choroidal neovascularization in age related macular degeneration
by: Tural Galbinur
Published: (2014-07-01)

Characterizing Macular Neovascularization in Myopic Macular Degeneration and Age-Related Macular Degeneration Using Swept Source OCTA
by: Sayah DN, et al.
Published: (2023-12-01)

Outcomes After Switching to Faricimab for Refractive Macular Edema in Treatment-Experienced Eyes with Neovascular Age-Related Macular Degeneration
by: Qaseem Y, et al.
Published: (2024-10-01)

Research progress in molecular omics of neovascular age-related macular degeneration
by: ZHUANG Xuenan, et al.
Published: (2025-02-01)

One-Year Outcomes of Faricimab Treatment for Aflibercept-Resistant Neovascular Age-Related Macular Degeneration
by: Rush RB
Published: (2023-08-01)

Quantitative assessment of choroidal parameters in type 1 macular neovascularization linked to central serous chorioretinopathy and neovascular age-related macular degeneration
by: Xiang-Gui Zhang, et al.
Published: (2024-10-01)

Macular Hole following Intravitreal Bevacizumab Injection in Choroidal Neovascularization Caused by Age-Related Macular Degeneration
by: Elad Moisseiev, et al.
Published: (2010-08-01)

Current and Novel Therapeutic Approaches for Treatment of Neovascular Age-Related Macular Degeneration
by: Reem H. ElSheikh, et al.
Published: (2022-11-01)

Volumetric fluid analysis of fixed monthly anti-VEGF treatment in patients with neovascular age-related macular degeneration
by: Bo Hee Kim, et al.
Published: (2023-06-01)

The Vascular Architecture of Macular Neovascularization in Age-Related Macular Degeneration as a Predictor of Therapy Requirements: A 3-Year Longitudinal Analysis
by: Michael Grün, et al.
Published: (2025-04-01)

Subretinal Transplant of Human Amniotic Membrane in Advanced Age-Related Macular Degeneration
by: Tomaso Caporossi, et al.
Published: (2022-11-01)

First-Year Real-Life Experience with Intravitreal Faricimab for Refractory Neovascular Age-Related Macular Degeneration
by: Wissam Aljundi, et al.
Published: (2024-03-01)

Quantitative Autofluorescence in Non-Neovascular Age Related Macular Degeneration
by: Shruti Chandra, et al.
Published: (2023-02-01)

Aflibercept, ranibizumab, and bevacizumab for macular neovascularization secondary to age-related macular degeneration: a retrospective OCT-angiography study
by: Marco Lombardo, et al.
Published: (2025-10-01)

Insights into myopic choroidal neovascularization based on quantitative proteomics analysis of the aqueous humor
by: Huimin Yu, et al.
Published: (2023-12-01)

Two-year results of switching to intravitreal administration of faricimab in patients with aflibercept-refractory neovascular age-related macular degeneration
by: Masaaki Saito, et al.
Published: (2025-08-01)

Treatment Strategies for Anti-VEGF Resistance in Neovascular Age-Related Macular Degeneration by Targeting Arteriolar Choroidal Neovascularization
by: Yingbin Fu, et al.
Published: (2024-02-01)

Mingjing granule inhibits the subretinal fibrovascular membrane of two-stage laser-induced neovascular age-related macular degeneration in rats
by: Xiaoyu Li, et al.
Published: (2024-06-01)

The Architecture of Macular Neovascularizations Predicts Treatment Responses to Anti-VEGF Therapy in Neovascular AMD
by: Henrik Faatz, et al.
Published: (2022-11-01)

Use of ranibizumab for the treatment of subretinal neovascularization in pathologic myopia: a prospective study
by: О.M. Blavatska, et al.
Published: (2016-06-01)