Intraocular amyloidosis with multifocal iris and anterior chamber translucent spherules

Ocular amylodosis, although a rare entity, is known to affect the conjunctiva, extraocular muscles, orbit, lacrimal gland, and skin around the eyes. Intraocular deposition of amyloid mainly confines to the vitreous and cornea. In this report, we describe two cases of intraocular amyloidosis presenti...

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Published in:Indian Journal of Ophthalmology
Main Authors: Sima Das, Sweety Tiple, Julie Pegu, Suneeta Dubey, Umang Mathur, Kaustabh Mulay, Carol L Shields
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2019-01-01
Subjects:
Online Access:http://www.ijo.in/article.asp?issn=0301-4738;year=2019;volume=67;issue=12;spage=2078;epage=2080;aulast=Das
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author Sima Das
Sweety Tiple
Julie Pegu
Suneeta Dubey
Umang Mathur
Kaustabh Mulay
Carol L Shields
author_facet Sima Das
Sweety Tiple
Julie Pegu
Suneeta Dubey
Umang Mathur
Kaustabh Mulay
Carol L Shields
author_sort Sima Das
collection DOAJ
container_title Indian Journal of Ophthalmology
description Ocular amylodosis, although a rare entity, is known to affect the conjunctiva, extraocular muscles, orbit, lacrimal gland, and skin around the eyes. Intraocular deposition of amyloid mainly confines to the vitreous and cornea. In this report, we describe two cases of intraocular amyloidosis presenting as multiple iris and anterior chamber cysts. Histopathological examination with special stain like Congo Red and Transmission Electron Microscopy confirmed the diagnosis of amyloidosis. Systemic investigations ruled out systemic association confirming the diagnosis of primary ocular amyloidosis.
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spelling doaj-art-6483711ac4384a7ca052d77f56acb8d72025-08-19T20:14:09ZengWolters Kluwer Medknow PublicationsIndian Journal of Ophthalmology0301-47381998-36892019-01-0167122078208010.4103/ijo.IJO_812_19Intraocular amyloidosis with multifocal iris and anterior chamber translucent spherulesSima DasSweety TipleJulie PeguSuneeta DubeyUmang MathurKaustabh MulayCarol L ShieldsOcular amylodosis, although a rare entity, is known to affect the conjunctiva, extraocular muscles, orbit, lacrimal gland, and skin around the eyes. Intraocular deposition of amyloid mainly confines to the vitreous and cornea. In this report, we describe two cases of intraocular amyloidosis presenting as multiple iris and anterior chamber cysts. Histopathological examination with special stain like Congo Red and Transmission Electron Microscopy confirmed the diagnosis of amyloidosis. Systemic investigations ruled out systemic association confirming the diagnosis of primary ocular amyloidosis.http://www.ijo.in/article.asp?issn=0301-4738;year=2019;volume=67;issue=12;spage=2078;epage=2080;aulast=Dasamyloidanterior chambereyeiris
spellingShingle Sima Das
Sweety Tiple
Julie Pegu
Suneeta Dubey
Umang Mathur
Kaustabh Mulay
Carol L Shields
Intraocular amyloidosis with multifocal iris and anterior chamber translucent spherules
amyloid
anterior chamber
eye
iris
title Intraocular amyloidosis with multifocal iris and anterior chamber translucent spherules
title_full Intraocular amyloidosis with multifocal iris and anterior chamber translucent spherules
title_fullStr Intraocular amyloidosis with multifocal iris and anterior chamber translucent spherules
title_full_unstemmed Intraocular amyloidosis with multifocal iris and anterior chamber translucent spherules
title_short Intraocular amyloidosis with multifocal iris and anterior chamber translucent spherules
title_sort intraocular amyloidosis with multifocal iris and anterior chamber translucent spherules
topic amyloid
anterior chamber
eye
iris
url http://www.ijo.in/article.asp?issn=0301-4738;year=2019;volume=67;issue=12;spage=2078;epage=2080;aulast=Das
work_keys_str_mv AT simadas intraocularamyloidosiswithmultifocalirisandanteriorchambertranslucentspherules
AT sweetytiple intraocularamyloidosiswithmultifocalirisandanteriorchambertranslucentspherules
AT juliepegu intraocularamyloidosiswithmultifocalirisandanteriorchambertranslucentspherules
AT suneetadubey intraocularamyloidosiswithmultifocalirisandanteriorchambertranslucentspherules
AT umangmathur intraocularamyloidosiswithmultifocalirisandanteriorchambertranslucentspherules
AT kaustabhmulay intraocularamyloidosiswithmultifocalirisandanteriorchambertranslucentspherules
AT carollshields intraocularamyloidosiswithmultifocalirisandanteriorchambertranslucentspherules