SFXN2 contributes mitochondrial dysfunction-induced apoptosis as a substrate of Parkin

IntroductionMitochondria, situated at the center of intricate signaling networks, play crucial roles in maintaining health and driving disease progression. SFXN2, a recently identified member of the mitochondrial transporter family, is localized to the outer mitochondrial membrane and regulates seve...

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Bibliographic Details

Published in:	Frontiers in Cellular Neuroscience
Main Authors:	Shishi Luo, Yechuan He, Yaohui He, Danling Wang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-08-01
Subjects:	SFXN2 Parkin ubiquitination apoptosis mitochondrial dysfunction
Online Access:	https://www.frontiersin.org/articles/10.3389/fncel.2025.1623747/full