Ldha-Dependent Metabolic Programs in Sertoli Cells Regulate Spermiogenesis in Mouse Testis
Sertoli cells play indispensable roles in spermatogenesis by providing the advanced germ cells with structural, nutritional, and regulatory support. Lactate is regarded as an essential Sertoli-cell-derived energy metabolite that nurses various types of spermatogenic cells; however, this assumption h...
| Published in: | Biology |
|---|---|
| Main Authors: | Xiao-Na Zhang, Hai-Ping Tao, Shuang Li, Yu-Jun Wang, Shi-Xin Wu, Bo Pan, Qi-En Yang |
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-12-01
|
| Subjects: | |
| Online Access: | https://www.mdpi.com/2079-7737/11/12/1791 |
Similar Items
Spermatogenesis and spermiogenesis in Didymocystis wedli Ariola, 1902 (Didymozoidae, Digenea)
by: MC Pamplona-Basilio, et al.
Published: (2001-11-01)
by: MC Pamplona-Basilio, et al.
Published: (2001-11-01)
Spermatogenesis without spermiogenesis in Laudakia caucasia (Reptilia: Agamidae): the role of hibernation
by: N. Rastegar-Pouyani, et al.
Published: (2007-05-01)
by: N. Rastegar-Pouyani, et al.
Published: (2007-05-01)
Isolation of Sertoli, Leydig, and spermatogenic cells from the mouse testis
by: Yao-Fu Chang, et al.
Published: (2011-11-01)
by: Yao-Fu Chang, et al.
Published: (2011-11-01)
Targeting and fusion proteins during mammalian spermiogenesis
by: JOÃO RAMALHO-SANTOS, et al.
Published: (2001-01-01)
by: JOÃO RAMALHO-SANTOS, et al.
Published: (2001-01-01)
HIPK4 is essential for murine spermiogenesis
by: J Aaron Crapster, et al.
Published: (2020-03-01)
by: J Aaron Crapster, et al.
Published: (2020-03-01)
The aryl hydrocarbon receptor: a new frontier in male reproductive system
by: Ghadeer Bustani, et al.
Published: (2025-05-01)
by: Ghadeer Bustani, et al.
Published: (2025-05-01)
Expression profile of sox5 and sox6 in sertoli and spermatogonial cells in growing mice testis
by: Zia Ur REHMAN, et al.
Published: (2019-10-01)
by: Zia Ur REHMAN, et al.
Published: (2019-10-01)
E4 Transcription Factor 1 (E4F1) Regulates Sertoli Cell Proliferation and Fertility in Mice
by: Rong-Ge Yan, et al.
Published: (2020-09-01)
by: Rong-Ge Yan, et al.
Published: (2020-09-01)
Sertoli cell-conditioned medium can improve blood-testis-barrier function and spermatogenesis in azoospermia mice induced by scrotal hyperthermia: An experimental study
by: Fakhroddin Aghajanpour, et al.
Published: (2024-02-01)
by: Fakhroddin Aghajanpour, et al.
Published: (2024-02-01)
Identification of differentially expressed genes in human testis biopsies with defective spermatogenesis
by: Shashika D. Kothalawala, et al.
Published: (2024-01-01)
by: Shashika D. Kothalawala, et al.
Published: (2024-01-01)
Updates in Sertoli Cell-Mediated Signaling During Spermatogenesis and Advances in Restoring Sertoli Cell Function
by: Victor A. Ruthig, et al.
Published: (2022-05-01)
by: Victor A. Ruthig, et al.
Published: (2022-05-01)
Differential Regulation of <i>TLE3</i> in Sertoli Cells of the Testes during Postnatal Development
by: Sangho Lee, et al.
Published: (2019-09-01)
by: Sangho Lee, et al.
Published: (2019-09-01)
Effect of androgens on Sertoli cell maturation in human testis from birth to puberty
by: Marion Lapoirie, et al.
Published: (2021-12-01)
by: Marion Lapoirie, et al.
Published: (2021-12-01)
PENGARUH TORSIO TESTIS TERHADAP GANGGUAN PROSES SPERMATOGENESIS PADA TESTIS TIKUS (Rattus norvegicus)
by: Nora Adliyanti Basar, et al.
Published: (2017-08-01)
by: Nora Adliyanti Basar, et al.
Published: (2017-08-01)
Two complementary approaches for efficient isolation of Sertoli cells for transcriptomic analysis
by: Jana Petrusová, et al.
Published: (2022-09-01)
by: Jana Petrusová, et al.
Published: (2022-09-01)
Exenatide and Dapagliflozin Combination Enhances Sertoli Cell Secretion of Key Metabolites for Spermatogenesis
by: João C. Ribeiro, et al.
Published: (2022-05-01)
by: João C. Ribeiro, et al.
Published: (2022-05-01)
Flurochloridone induced abnormal spermatogenesis by damaging testicular Sertoli cells in mice
by: Weiqi Sun, et al.
Published: (2022-11-01)
by: Weiqi Sun, et al.
Published: (2022-11-01)
Dataset of differentially expressed genes in mouse P12 testes in response to the loss of ATRX in Sertoli cells
by: Stefan Bagheri-Fam, et al.
Published: (2022-06-01)
by: Stefan Bagheri-Fam, et al.
Published: (2022-06-01)
Spermiogenesis and sperm ultrastructure in Calicotyle affinis Scott, 1911 (Platyhelminthes, Monogenea, Monopisthocotylea, Monocotylidae)
by: Bruňanská M., et al.
Published: (2017-12-01)
by: Bruňanská M., et al.
Published: (2017-12-01)
Impact of endocrine disrupting chemicals and pharmaceuticals on Sertoli cell development and functions
by: Maia Corpuz-Hilsabeck, et al.
Published: (2023-01-01)
by: Maia Corpuz-Hilsabeck, et al.
Published: (2023-01-01)
Map-1a regulates Sertoli cell BTB dynamics through the cytoskeletal organization of microtubule and F-actin
by: Lingling Wang, et al.
Published: (2024-04-01)
by: Lingling Wang, et al.
Published: (2024-04-01)
Research progress on Sertoli cell secretion during spermatogenesis
by: Yao Xiao, et al.
Published: (2025-01-01)
by: Yao Xiao, et al.
Published: (2025-01-01)
Insights into the Mechanism of Bovine Spermiogenesis Based on Comparative Transcriptomic Studies
by: Xin Li, et al.
Published: (2021-01-01)
by: Xin Li, et al.
Published: (2021-01-01)
The sclerosing sertoli cell tumor of the testis: a case report
by: Xueyao Tang, et al.
Published: (2023-05-01)
by: Xueyao Tang, et al.
Published: (2023-05-01)
The involvement of the nuclear lamina in human and rodent spermiogenesis: a systematic review
by: Marine Paci, et al.
Published: (2018-06-01)
by: Marine Paci, et al.
Published: (2018-06-01)
Importance of the Androgen Receptor Signaling in Gene Transactivation and Transrepression for Pubertal Maturation of the Testis
by: Nadia Y. Edelsztein, et al.
Published: (2019-08-01)
by: Nadia Y. Edelsztein, et al.
Published: (2019-08-01)
Ultrastructural aspects of spermatogonesis in Metamicrocotyla macracantha (Alexander, 1954) Koratha, 1955 (Monogenea; Microcotylidae)
by: Maria de Fatima Diniz Baptista Farias, et al.
Published: (1995-10-01)
by: Maria de Fatima Diniz Baptista Farias, et al.
Published: (1995-10-01)
Loss of Cx43 in Murine Sertoli Cells Leads to Altered Prepubertal Sertoli Cell Maturation and Impairment of the Mitosis-Meiosis Switch
by: Erika Hilbold, et al.
Published: (2020-03-01)
by: Erika Hilbold, et al.
Published: (2020-03-01)
TMPRSS12 Functions in Meiosis and Spermiogenesis and Is Required for Male Fertility in Mice
by: Jingjing Zhang, et al.
Published: (2022-04-01)
by: Jingjing Zhang, et al.
Published: (2022-04-01)
Running the gauntlet: challenges to genome integrity in spermiogenesis
by: Maiko Kitaoka, et al.
Published: (2024-12-01)
by: Maiko Kitaoka, et al.
Published: (2024-12-01)
RNF20 is required for male fertility through regulation of H2B ubiquitination in the Sertoli cells
by: Fengling Lai, et al.
Published: (2023-04-01)
by: Fengling Lai, et al.
Published: (2023-04-01)
Interaction between Chromodomain Y-like Protein and Androgen Receptor Signaling in Sertoli Cells Accounts for Spermatogenesis
by: Kuo-Chung Lan, et al.
Published: (2024-05-01)
by: Kuo-Chung Lan, et al.
Published: (2024-05-01)
The Microtubule Cytoskeleton during the Early <i>Drosophila</i> Spermiogenesis
by: Maria Giovanna Riparbelli, et al.
Published: (2020-12-01)
by: Maria Giovanna Riparbelli, et al.
Published: (2020-12-01)
Effects of Lycium barbarum polysaccharides on the proliferation and differentiation of primary Sertoli cells in young rats
by: Suqin Hu, et al.
Published: (2022-01-01)
by: Suqin Hu, et al.
Published: (2022-01-01)
Spermiogenesis, Stages of Seminiferous Epithelium and Variations in Seminiferous Tubules during Active States of Spermatogenesis in Yangzhou Goose Ganders
by: Muhammad Faheem Akhtar, et al.
Published: (2020-03-01)
by: Muhammad Faheem Akhtar, et al.
Published: (2020-03-01)
STEREOLOGICAL QUANTITATION OF LEYDIG AND SERTOLI CELLS IN THE TESTIS FROM YOUNG AND OLD MEN
by: Peter M Petersen, et al.
Published: (2011-05-01)
by: Peter M Petersen, et al.
Published: (2011-05-01)
Mouse SPAG6L, a Key Cytoskeleton Modulator Essential for Male Germ Cell Development, Is Not Required for Sertoli Cell Function
by: Tao Li, et al.
Published: (2025-05-01)
by: Tao Li, et al.
Published: (2025-05-01)
ASB1 engages with ELOB to facilitate SQOR ubiquitination and H2S homeostasis during spermiogenesis
by: Jinxing Lv, et al.
Published: (2025-02-01)
by: Jinxing Lv, et al.
Published: (2025-02-01)
Low XIST expression in Sertoli cells of Klinefelter syndrome patients causes high susceptibility of these cells to an extra X chromosome
by: Liang-Yu Zhao, et al.
Published: (2023-01-01)
by: Liang-Yu Zhao, et al.
Published: (2023-01-01)
Enhanced autophagy reversed aflatoxin B1-induced decrease in lactate secretion of dairy goat Sertoli cells
by: Shuaiqi Han, et al.
Published: (2023-07-01)
by: Shuaiqi Han, et al.
Published: (2023-07-01)
Similar Items
-
Spermatogenesis and spermiogenesis in Didymocystis wedli Ariola, 1902 (Didymozoidae, Digenea)
by: MC Pamplona-Basilio, et al.
Published: (2001-11-01) -
Spermatogenesis without spermiogenesis in Laudakia caucasia (Reptilia: Agamidae): the role of hibernation
by: N. Rastegar-Pouyani, et al.
Published: (2007-05-01) -
Isolation of Sertoli, Leydig, and spermatogenic cells from the mouse testis
by: Yao-Fu Chang, et al.
Published: (2011-11-01) -
Targeting and fusion proteins during mammalian spermiogenesis
by: JOÃO RAMALHO-SANTOS, et al.
Published: (2001-01-01) -
HIPK4 is essential for murine spermiogenesis
by: J Aaron Crapster, et al.
Published: (2020-03-01)
