Prostate specific membrane antigen positron emission tomography for lesion-directed high-dose-rate brachytherapy dose escalation

Background and purpose: Prostate specific membrane antigen positron emission tomography imaging (PSMA-PET) has demonstrated potential for intra-prostatic lesion localization. We leveraged our existing database of co-registered PSMA-PET imaging with cross sectional digitized pathology to model dose c...

Full description

Bibliographic Details
Published in:	Physics and Imaging in Radiation Oncology
Main Authors:	Christopher W. Smith, Ryan Alfano, Douglas Hoover, Kathleen Surry, David D'Souza, Jonathan Thiessen, Irina Rachinsky, John Butler, Jose A. Gomez, Mena Gaed, Madeleine Moussa, Joseph Chin, Stephen Pautler, Glenn S. Bauman, Aaron D. Ward
Format:	Article
Language:	English
Published:	Elsevier 2021-07-01
Subjects:	Prostate cancer Positron emission tomography High dose rate brachytherapy Dominant intraprostatic lesion Targeted radiation therapy
Online Access:	http://www.sciencedirect.com/science/article/pii/S2405631621000361

Similar Items

Short-duration dynamic [18F]DCFPyL PET and CT perfusion imaging to localize dominant intraprostatic lesions in prostate cancer: validation against digital histopathology and comparison to [18F]DCFPyL PET/MR at 120 minutes
by: Dae-Myoung Yang, et al.
Published: (2021-10-01)

Proton versus photon therapy for high-risk prostate cancer with dose escalation of dominant intraprostatic lesions: a preliminary planning study
by: Ashley Li Kuan Ong, et al.
Published: (2023-11-01)

Comparison of two high dose rate brachytherapy regimes
by: Gaurav Jaswal, et al.
Published: (2023-01-01)

Method of Dose Delivery in Brachytherapy for Cervical Cancer
by: D. I. Kazlouski, et al.
Published: (2023-03-01)

Clinical Efficacy and Openness to New Challenges of Low Dose Rate Brachytherapy for Prostate Cancer
by: Manabu Kato, et al.
Published: (2023-11-01)

Dose differentiated high-dose-rate prostate brachytherapy: a feasibility assessment of MRI-guided dose escalation to dominant intra-prostatic lesions
by: Christopher Luminais, et al.
Published: (2022-10-01)

Dose escalation in oropharyngeal cancer: a comparison of simultaneous integrated boost and brachytherapy boost
by: Anna Embring, et al.
Published: (2023-04-01)

Endoscopic Ultrasound‐Guided Brachytherapy of Yttrium‐90 Implantation Into Pancreas: A Dose‐Escalation Pilot Study
by: Yuchong Zhao, et al.
Published: (2025-03-01)

Single-fraction image-guided high-dose-rate brachytherapy for head and neck cancer: three cases of palliative brachytherapy
by: Yoshiaki Ota, et al.
Published: (2020-06-01)

Bounce effect or local recurrence after low-dose-rate brachytherapy of the prostate? When prostate-specific membrane antigen positron emission tomography–computed tomography is false positive: a case report
by: Tamas Rozsos, et al.
Published: (2025-05-01)

A review of whole gland prostate brachytherapy with focal dose escalation to intra-prostatic lesions: Clinical efficacy and technical aspects
by: Joel Poder, et al.
Published: (2024-10-01)

Clinical audit of dose-escalated radical radiotherapy for advanced cervical carcinoma using a pragmatic protocol (3 fractions of 8 Gy HDR brachytherapy)
by: Jyotirup Goswami, et al.
Published: (2021-08-01)

Re‐salvage focal low‐dose rate brachytherapy for local recurrence of prostate cancer after salvage focal low‐dose rate brachytherapy
by: Takahiro Nakamoto, et al.
Published: (2024-01-01)

Current status and future readiness of Indian radiation oncologists to embrace prostate high-dose-rate brachytherapy: An Indian Brachytherapy Society survey
by: Susovan Banerjee, et al.
Published: (2023-12-01)

Combined interstitial and surface high-dose-rate brachytherapy treatment of squamous cell carcinoma of the hand
by: Daniel Kim, et al.
Published: (2020-01-01)

Transrectal ultrasound-guided intraprostatic injection therapy for treatment of chronic prostatitis in a Ugandan population
by: Michael G. Kawooya, et al.
Published: (2024-11-01)

HIGH DOSE-RATE BRACHYTHERAPY IN THE TREATMENT OF CERVICAL CANCER
by: M. V. Kiseleva, et al.
Published: (2018-08-01)

Outcomes and dose—volume parameters for computed tomography-based brachytherapy planning for vaginal recurrence of uterine cancer primarily treated with surgery
by: Keiko Nemoto Murofushi, et al.
Published: (2021-06-01)

Low-dose-rate, high-dose-rate, and pulsed-dose-rate intra-cavitary brachytherapy for cervical cancer: The very first comparison study
by: Daya Nand Sharma, et al.
Published: (2024-09-01)

High-dose rate brachytherapy in the treatment of cancer of the cervix uteri
by: D. A. Aliyev, et al.
Published: (2014-07-01)

Dose perturbation study in a multichannel breast brachytherapy device
by: Indra J. Das, et al.
Published: (2011-12-01)

Impact of androgen deprivation therapy in patients with unfavorable intermediate-risk prostate cancer receiving brachytherapy-based dose-escalated radiation therapy
by: Nikhil T. Sebastian, et al.
Published: (2024-09-01)

Treatment patterns of high-dose-rate and low-dose-rate brachytherapy as monotherapy for prostate cancer
by: Justin Barnes, et al.
Published: (2019-07-01)

Dose escalation with stereotactic body radiotherapy for cervical cancer treatment
by: Menekse Turna, et al.
Published: (2024-10-01)

Quality of life after high-dose-rate brachytherapy monotherapy for prostate cancer
by: Jessika A. Contreras, et al.
Published: (2015-02-01)

Mathematical Models Used for Brachytherapy Treatment Planning Dose Calculation Algorithms
by: Shefali Kanwar, et al.
Published: (2023-08-01)

Skin marker for MR-only surface high-dose-rate brachytherapy
by: Evangelia Kaza, et al.
Published: (2025-02-01)

The Influence of Au, Gd and I Nanoparticles on Radiation Dose Absorption during High Dose Rate Brachytherapy with 192Ir Source
by: Peter Damian, et al.
Published: (2025-05-01)

The use of Lutetium-177 PSMA radioligand therapy with high dose rate brachytherapy for locally recurrent prostate cancer after previous definitive radiation therapy: a randomized, single-institution, phase I/II study (ROADSTER).
by: Lucas C. Mendez, et al.
Published: (2023-04-01)

Innovations in brachytherapy
by: Joshua Lim, et al.
Published: (2025-01-01)

Impact of different dose prescription schedules on EQD2 in high-dose-rate intracavitary brachytherapy of carcinoma cervix
by: Mohan Kumar, et al.
Published: (2019-04-01)

The irreplaceable art of brachytherapy: A technical note on interstitial high-dose-rate interventional radiotherapy (brachytherapy) in eyelid tumors
by: Tanvir Pasha, et al.
Published: (2025-06-01)

Salvage brachytherapy for locally recurrent prostate cancer after single-fraction 19 Gy high-dose-rate brachytherapy: toxicity, prostate-specific antigen kinetics, and cancer control
by: Esther Mayrata, et al.
Published: (2021-02-01)

Multiple direction needle-path planning and inverse dose optimization for robotic low-dose rate brachytherapy
by: Philipp Aumüller, et al.
Published: (2022-05-01)

Assessment of dose to vaginal mucosa for gynecologic template interstitial high-dose-rate brachytherapy using Monte Carlo simulation
by: Devin Van Elburg, et al.
Published: (2023-10-01)

Clinical implementation of failure modes and effects analysis for gynecological high-dose-rate brachytherapy
by: Siyao Liu, et al.
Published: (2024-02-01)

Focal low-dose-rate prostate brachytherapy for low- and intermediate-risk prostate cancer
by: Hiroaki Kunogi, et al.
Published: (2020-12-01)

Evaluation of doses to pelvic lymph node regions from image-guided high-dose-rate interstitial brachytherapy for carcinoma of the uterine cervix
by: Ajeet Gandhi, et al.
Published: (2023-08-01)

The impact of different treatment protocols on achieved radiation doses of high-dose-rate brachytherapy for locally advanced cervical cancer: a comparison between 2 fractions in 1 application and separate applications for each fraction
by: Ester Jääskeläinen, et al.
Published: (2022-11-01)

TREATMENT OUTCOMES OF EXTERNAL BEAM RADIOTHERAPY COMBINED WITH HIGH-DOSE-RATE BRACHYTHERAPY IN PATIENTS WITH ESOPHAGEAL CANCER
by: A. A. Lozhkov, et al.
Published: (2017-03-01)