Sestrin2 knockout exacerbates high-fat diet induced metabolic disorders and complications in female mice

Abstract Background Obesity and its associated complications raise significant public concern, revealing gender disparities in the susceptibility to metabolic disorders, with females often displaying greater resistance to obesity-related metabolic disorder than males. Sestrin2 is a crucial protein i...

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Bibliographic Details

Published in:	Nutrition & Metabolism
Main Authors:	Le Zhang, Chengxia Kan, Junfeng Shi, Hongyan Qiu, Jingwen Zhang, Wenli Ding, Linfei Xu, Kexin Zhang, Zhentao Guo, Ningning Hou, Xiaodong Sun, Fang Han
Format:	Article
Language:	English
Published:	BMC 2024-08-01
Subjects:	Sestrin2 Obesity Female UCP-1 Adipose tissue
Online Access:	https://doi.org/10.1186/s12986-024-00834-8