Old but New: Group IIA Phospholipase A<sub>2</sub> as a Modulator of Gut Microbiota
Among the phospholipase A<sub>2</sub> (PLA<sub>2</sub>) superfamily, the secreted PLA<sub>2</sub> (sPLA<sub>2</sub>) family contains 11 mammalian isoforms that exhibit unique tissue or cellular distributions and enzymatic properties. Current studies us...
| Published in: | Metabolites |
|---|---|
| Main Authors: | Yoshitaka Taketomi, Yoshimi Miki, Makoto Murakami |
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-04-01
|
| Subjects: | |
| Online Access: | https://www.mdpi.com/2218-1989/12/4/352 |
Similar Items
Mast Cell-Specific Deletion of Group III Secreted Phospholipase A<sub>2</sub> Impairs Mast Cell Maturation and Functions
by: Yoshitaka Taketomi, et al.
Published: (2021-07-01)
by: Yoshitaka Taketomi, et al.
Published: (2021-07-01)
A Lipidomic Perspective of the Action of Group IIA Secreted Phospholipase A<sub>2</sub> on Human Monocytes: Lipid Droplet Biogenesis and Activation of Cytosolic Phospholipase A<sub>2</sub>α
by: Juan P. Rodríguez, et al.
Published: (2020-06-01)
by: Juan P. Rodríguez, et al.
Published: (2020-06-01)
Lipid Profile of Activated Macrophages and Contribution of Group V Phospholipase A<sub>2</sub>
by: Masaya Koganesawa, et al.
Published: (2020-12-01)
by: Masaya Koganesawa, et al.
Published: (2020-12-01)
Structural and Functional Aspects of Targeting the Secreted Human Group IIA Phospholipase A<sub>2</sub>
by: Ryung Rae Kim, et al.
Published: (2020-09-01)
by: Ryung Rae Kim, et al.
Published: (2020-09-01)
Lipid Droplets, Phospholipase A<sub>2</sub>, Arachidonic Acid, and Atherosclerosis
by: Miguel A. Bermúdez, et al.
Published: (2021-12-01)
by: Miguel A. Bermúdez, et al.
Published: (2021-12-01)
One-Step Affinity Purification of Leucine-Rich α<sub>2</sub>-Glycoproteins from Snake Sera and Characterization of Their Phospholipase A<sub>2</sub>-Inhibitory Activities as β-Type Phospholipase A<sub>2</sub> Inhibitors
by: Ryoichi Shirai, et al.
Published: (2024-03-01)
by: Ryoichi Shirai, et al.
Published: (2024-03-01)
Sinapicacid Inhibits Group IIA Secretory Phospholipase A<sub>2</sub> and Its Inflammatory Response in Mice
by: Aladahalli S. Giresha, et al.
Published: (2022-06-01)
by: Aladahalli S. Giresha, et al.
Published: (2022-06-01)
The Contribution of Cytosolic Group IVA and Calcium-Independent Group VIA Phospholipase A<sub>2</sub>s to Adrenic Acid Mobilization in Murine Macrophages
by: Patricia Monge, et al.
Published: (2020-04-01)
by: Patricia Monge, et al.
Published: (2020-04-01)
Inflammatory Effects of <i>Bothrops</i> Phospholipases A<sub>2</sub>: Mechanisms Involved in Biosynthesis of Lipid Mediators and Lipid Accumulation
by: Vanessa Moreira, et al.
Published: (2021-12-01)
by: Vanessa Moreira, et al.
Published: (2021-12-01)
The Role of Calcium-Independent Phospholipase A<sub>2</sub> in the Molecular Mechanisms of Schizophrenia
by: Shoji Nakamura
Published: (2025-08-01)
by: Shoji Nakamura
Published: (2025-08-01)
Rapid Identification of Phospholipase A<sub>2</sub> Transcripts from Snake Venoms
by: Ying Jia, et al.
Published: (2019-01-01)
by: Ying Jia, et al.
Published: (2019-01-01)
Secreted Phospholipase A<sub>2</sub>-IIA Modulates Transdifferentiation of Cardiac Fibroblast through EGFR Transactivation: An Inflammation–Fibrosis Link
by: Ruben Martin, et al.
Published: (2020-02-01)
by: Ruben Martin, et al.
Published: (2020-02-01)
Phospholipase A<sub>2</sub> Drives Tumorigenesis and Cancer Aggressiveness through Its Interaction with Annexin A1
by: Lara Vecchi, et al.
Published: (2021-06-01)
by: Lara Vecchi, et al.
Published: (2021-06-01)
Inhibition of cytosolic Phospholipase A<sub>2</sub> prevents prion peptide-induced neuronal damage and co-localisation with Beta III Tubulin
by: Last Victoria, et al.
Published: (2012-08-01)
by: Last Victoria, et al.
Published: (2012-08-01)
Possible Involvement of Intracellular Calcium-Independent Phospholipase A<sub>2</sub> in the Release of Secretory Phospholipases from Mast Cells—Increased Expression in Ileal Mast Cells of Crohn’s Disease
by: Ulrika Christerson, et al.
Published: (2019-07-01)
by: Ulrika Christerson, et al.
Published: (2019-07-01)
Current Knowledge on Mammalian Phospholipase A<sub>1</sub>, Brief History, Structures, Biochemical and Pathophysiological Roles
by: Shun Yaginuma, et al.
Published: (2022-04-01)
by: Shun Yaginuma, et al.
Published: (2022-04-01)
Contextual Constraints: Dynamic Evolution of Snake Venom Phospholipase A<sub>2</sub>
by: Vivek Suranse, et al.
Published: (2022-06-01)
by: Vivek Suranse, et al.
Published: (2022-06-01)
A Lipidomic Approach to Studying the Downregulation of Free Fatty Acids by Cytosolic Phospholipase A<sub>2</sub> Inhibitors
by: Asimina Bourboula, et al.
Published: (2025-04-01)
by: Asimina Bourboula, et al.
Published: (2025-04-01)
Isolation and Characterization of A2-EPTX-Nsm1a, a Secretory Phospholipase A<sub>2</sub> from Malaysian Spitting Cobra (<i>Naja sumatrana</i>) Venom
by: Nur Atiqah Haizum Abdullah, et al.
Published: (2021-12-01)
by: Nur Atiqah Haizum Abdullah, et al.
Published: (2021-12-01)
A Representative GIIA Phospholipase A<sub>2</sub> Activates Preadipocytes to Produce Inflammatory Mediators Implicated in Obesity Development
by: Elbio Leiguez, et al.
Published: (2020-11-01)
by: Elbio Leiguez, et al.
Published: (2020-11-01)
Updating Phospholipase A<sub>2</sub> Biology
by: Makoto Murakami, et al.
Published: (2020-10-01)
by: Makoto Murakami, et al.
Published: (2020-10-01)
Study of the cytotoxic effect of secretory phospholipase A<sub>2</sub> of <i>Vipera nikolskii</i> venom on the model of HeLа and ECV340 cell lines
by: M. A. Solovyeva, et al.
Published: (2024-12-01)
by: M. A. Solovyeva, et al.
Published: (2024-12-01)
The Contribution of Phospholipase A<sub>2</sub> and Metalloproteinases to the Synergistic Action of Viper Venom on the Bioenergetic Profile of Vero Cells
by: Naira Ayvazyan, et al.
Published: (2022-10-01)
by: Naira Ayvazyan, et al.
Published: (2022-10-01)
Group V Phospholipase A<sub>2</sub> Mediates Endothelial Dysfunction and Acute Lung Injury Caused by Methicillin-Resistant <i>Staphylococcus Aureus</i>
by: Yu Maw Htwe, et al.
Published: (2021-07-01)
by: Yu Maw Htwe, et al.
Published: (2021-07-01)
The Lysophospholipase PNPLA7 Controls Hepatic Choline and Methionine Metabolism
by: Sayaka Harada, et al.
Published: (2023-03-01)
by: Sayaka Harada, et al.
Published: (2023-03-01)
Outtakes from My Journey through the World of LIPID MAPS
by: Edward A. Dennis
Published: (2022-06-01)
by: Edward A. Dennis
Published: (2022-06-01)
Secretory Phospholipase A<sub>2</sub>-IIA Protein and mRNA Pools in Extracellular Vesicles of Bronchoalveolar Lavage Fluid from Patients with Early Acute Respiratory Distress Syndrome: A New Perception in the Dissemination of Inflammation?
by: Stylianos Papadopoulos, et al.
Published: (2020-11-01)
by: Stylianos Papadopoulos, et al.
Published: (2020-11-01)
Effects of the Heterodimeric Neurotoxic Phospholipase A<sub>2</sub> from the Venom of <i>Vipera nikolskii</i> on the Contractility of Rat Papillary Muscles and Thoracic Aortas
by: Alexey Averin, et al.
Published: (2024-02-01)
by: Alexey Averin, et al.
Published: (2024-02-01)
Promising Immobilization of Industrial-Class Phospholipase A<sub>1</sub> to Attain High-Yield Phospholipids Hydrolysis and Repeated Use with Optimal Water Content in Water-in-Oil Microemulsion Phase
by: Yusuke Hayakawa, et al.
Published: (2021-02-01)
by: Yusuke Hayakawa, et al.
Published: (2021-02-01)
A Biochemical and Pharmacological Characterization of Phospholipase A<sub>2</sub> and Metalloproteinase Fractions from Eastern Russell’s Viper (<i>Daboia siamensis</i>) Venom: Two Major Components Associated with Acute Kidney Injury
by: Janeyuth Chaisakul, et al.
Published: (2021-07-01)
by: Janeyuth Chaisakul, et al.
Published: (2021-07-01)
Cellular Plasmalogen Content Does Not Influence Arachidonic Acid Levels or Distribution in Macrophages: A Role for Cytosolic Phospholipase A<sub>2</sub>γ in Phospholipid Remodeling
by: Patricia Lebrero, et al.
Published: (2019-07-01)
by: Patricia Lebrero, et al.
Published: (2019-07-01)
Identification of a Dual Inhibitor of Secreted Phospholipase A<sub>2</sub> (GIIA sPLA<sub>2</sub>) and SARS-CoV-2 Main Protease
by: Maria A. Theodoropoulou, et al.
Published: (2022-08-01)
by: Maria A. Theodoropoulou, et al.
Published: (2022-08-01)
Metabolic Effects of Selective Deletion of Group VIA Phospholipase A<sub>2</sub> from Macrophages or Pancreatic Islet Beta-Cells
by: John Turk, et al.
Published: (2020-10-01)
by: John Turk, et al.
Published: (2020-10-01)
Expression of a bee-venom phospholipase A<sub>2</sub> gene from Apis mellifera in Escherichia coli
by: SHEN Li-rong, et al.
Published: (2004-01-01)
by: SHEN Li-rong, et al.
Published: (2004-01-01)
The Cytosolic Phospholipase A<sub>2</sub>α N-Terminal C2 Domain Binds and Oligomerizes on Membranes with Positive Curvature
by: Katherine E. Ward, et al.
Published: (2020-04-01)
by: Katherine E. Ward, et al.
Published: (2020-04-01)
Heterologous Expression and Immunogenic Potential of the Most Abundant Phospholipase A<sub>2</sub> from Coral Snake <i>Micrurus dumerilii</i> to Develop Antivenoms
by: Luz E. Romero-Giraldo, et al.
Published: (2022-11-01)
by: Luz E. Romero-Giraldo, et al.
Published: (2022-11-01)
An Experimental Model of Acute Pulmonary Damage Induced by the Phospholipase A<sub>2</sub>-Rich Venom of the Snake <i>Pseudechis papuanus</i>
by: Daniela Solano, et al.
Published: (2025-06-01)
by: Daniela Solano, et al.
Published: (2025-06-01)
Alterations in β-Cell Sphingolipid Profile Associated with ER Stress and iPLA<sub>2</sub>β: Another Contributor to β-Cell Apoptosis in Type 1 Diabetes
by: Tomader Ali, et al.
Published: (2021-10-01)
by: Tomader Ali, et al.
Published: (2021-10-01)
Role of Microbiota-Derived Hydrogen Sulfide (H<sub>2</sub>S) in Modulating the Gut–Brain Axis: Implications for Alzheimer’s and Parkinson’s Disease Pathogenesis
by: Constantin Munteanu, et al.
Published: (2024-11-01)
by: Constantin Munteanu, et al.
Published: (2024-11-01)
Aflatoxin B<sub>1</sub> Exposure in Sheep: Insights into Hepatotoxicity Based on Oxidative Stress, Inflammatory Injury, Apoptosis, and Gut Microbiota Analysis
by: Yuzhen Sui, et al.
Published: (2022-12-01)
by: Yuzhen Sui, et al.
Published: (2022-12-01)
Similar Items
-
Mast Cell-Specific Deletion of Group III Secreted Phospholipase A<sub>2</sub> Impairs Mast Cell Maturation and Functions
by: Yoshitaka Taketomi, et al.
Published: (2021-07-01) -
A Lipidomic Perspective of the Action of Group IIA Secreted Phospholipase A<sub>2</sub> on Human Monocytes: Lipid Droplet Biogenesis and Activation of Cytosolic Phospholipase A<sub>2</sub>α
by: Juan P. Rodríguez, et al.
Published: (2020-06-01) -
Lipid Profile of Activated Macrophages and Contribution of Group V Phospholipase A<sub>2</sub>
by: Masaya Koganesawa, et al.
Published: (2020-12-01) -
Structural and Functional Aspects of Targeting the Secreted Human Group IIA Phospholipase A<sub>2</sub>
by: Ryung Rae Kim, et al.
Published: (2020-09-01) -
Lipid Droplets, Phospholipase A<sub>2</sub>, Arachidonic Acid, and Atherosclerosis
by: Miguel A. Bermúdez, et al.
Published: (2021-12-01)
