Microvascular Dysfunction Is Associated With Impaired Myocardial Work in Obstructive and Nonobstructive Hypertrophic Cardiomyopathy: A Multimodality Study
Background Two‐dimensional speckle tracking echocardiography has been shown to correlate with microvascular dysfunction, a hallmark of hypertrophic cardiomyopathy (HCM). We hypothesized that there is an association between myocardial work and left ventricular ischemia, with incremental value to glob...
| Published in: | Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease |
|---|---|
| Main Authors: | Pedro Garcia Brás, Sílvia Aguiar Rosa, Isabel Cardoso, Luísa Moura Branco, Ana Galrinho, António Valentim Gonçalves, Boban Thomas, José Miguel Viegas, António Fiarresga, Gonçalo Branco, Ricardo Pereira, Mafalda Selas, Filipa Silva, Inês Cruz, Luís Baquero, Rui Cruz Ferreira, Luís Rocha Lopes |
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2023-04-01
|
| Subjects: | |
| Online Access: | https://www.ahajournals.org/doi/10.1161/JAHA.122.028857 |
Similar Items
Cardiovascular magnetic resonance detects microvascular dysfunction in a mouse model of hypertrophic cardiomyopathy
by: Min-Chi Ku, et al.
Published: (2021-05-01)
by: Min-Chi Ku, et al.
Published: (2021-05-01)
Assessment of myocardial work in sarcomere gene mutation carriers, healthy controls and overt nonobstructive hypertrophic cardiomyopathy
by: Carla Marques Pires, et al.
Published: (2025-02-01)
by: Carla Marques Pires, et al.
Published: (2025-02-01)
The Impact of Ischemia Assessed by Magnetic Resonance on Functional, Arrhythmic, and Imaging Features of Hypertrophic Cardiomyopathy
by: Sílvia Aguiar Rosa, et al.
Published: (2021-12-01)
by: Sílvia Aguiar Rosa, et al.
Published: (2021-12-01)
Improvement in coronary microvascular dysfunction evaluated by cardiac magnetic resonance in patients with hypertrophic obstructive cardiomyopathy after transapical beating-heart septal myectomy
by: Yun Zhao, et al.
Published: (2023-10-01)
by: Yun Zhao, et al.
Published: (2023-10-01)
Left Ventricular Noncompaction Masquerading as Hypertrophic Nonobstructive Cardiomyopathy
by: Praveen Rermal Veedu, et al.
Published: (2023-01-01)
by: Praveen Rermal Veedu, et al.
Published: (2023-01-01)
Ultrasound study of right ventricular myocardial perfusion and functional changes in hypertrophic cardiomyopathy
by: Shan Cao, et al.
Published: (2024-01-01)
by: Shan Cao, et al.
Published: (2024-01-01)
Identifying Obstructive Hypertrophic Cardiomyopathy from Nonobstructive Hypertrophic Cardiomyopathy: Development and Validation of a Model Based on Electrocardiogram Features
by: Lanyan Guo, et al.
Published: (2023-08-01)
by: Lanyan Guo, et al.
Published: (2023-08-01)
Early left ventricular microvascular dysfunction in diabetic pigs: a longitudinal quantitative myocardial perfusion CMR study
by: Li Jiang, et al.
Published: (2024-01-01)
by: Li Jiang, et al.
Published: (2024-01-01)
Myocardial bridging in obstructive hypertrophic cardiomyopathy: a risk factor for myocardial fibrosis
by: Changpeng Song, et al.
Published: (2024-02-01)
by: Changpeng Song, et al.
Published: (2024-02-01)
Associations between perfusion defects, tissue changes and myocardial deformation in hypertrophic cardiomyopathy, uncovered by a cardiac magnetic resonance segmental analysis
by: Pedro Garcia Brás, et al.
Published: (2022-07-01)
by: Pedro Garcia Brás, et al.
Published: (2022-07-01)
Definitional Challenges in Understanding Hypertrophic Cardiomyopathy
by: Jan M. Federspiel, et al.
Published: (2024-11-01)
by: Jan M. Federspiel, et al.
Published: (2024-11-01)
Evaluation of diastolic dysfunction in children with hypertrophic cardiomyopathy and its relationship with development of myocardial fibrosis
by: Salem Elsayed Deraz, et al.
Published: (2023-06-01)
by: Salem Elsayed Deraz, et al.
Published: (2023-06-01)
Clinical Outcomes in Patients With Nonobstructive, Labile, and Obstructive Hypertrophic Cardiomyopathy
by: Dai‐Yin Lu, et al.
Published: (2018-03-01)
by: Dai‐Yin Lu, et al.
Published: (2018-03-01)
CMR of microvascular obstruction and hemorrhage in myocardial infarction
by: Wu Katherine C
Published: (2012-09-01)
by: Wu Katherine C
Published: (2012-09-01)
Elevated high-sensitivity troponin T levels are associated with adverse cardiac remodelling and myocardial fibrosis in hypertrophic cardiomyopathy
by: Stefanie Hasler, et al.
Published: (2016-03-01)
by: Stefanie Hasler, et al.
Published: (2016-03-01)
Systemic inflammation is associated with myocardial fibrosis in patients with obstructive hypertrophic cardiomyopathy
by: Xinli Guo, et al.
Published: (2025-02-01)
by: Xinli Guo, et al.
Published: (2025-02-01)
RARE CASES OF HYPERTROPHIC CARDIOMYOPATHY: VARIANTS AND CLINICAL OBSERVATIONS
by: V. Yu. Zimina, et al.
Published: (2015-09-01)
by: V. Yu. Zimina, et al.
Published: (2015-09-01)
Microvascular dysfunction causing myocardial ischemia in obstructive hypertrophic cardiomyopathy
by: Nonthikorn Theerasuwipakorn, MD, MSc, et al.
Published: (2025-04-01)
by: Nonthikorn Theerasuwipakorn, MD, MSc, et al.
Published: (2025-04-01)
Association between peripheral and coronary microvascular function and the impact of myocardial bridging
by: Takumi Toya, et al.
Published: (2025-04-01)
by: Takumi Toya, et al.
Published: (2025-04-01)
Specifics of Left Ventricular Hypertrophy and Characteristic of Phenotypic Variants in Patients with Hypertrophic Cardiomyopathy
by: G. I. Ignatenko, et al.
Published: (2023-08-01)
by: G. I. Ignatenko, et al.
Published: (2023-08-01)
Prognostic value of morphological, biochemical, molecular markers of fibrosis in patients with hypertrophic cardiomyopathy
by: G. A. Burnasheva, et al.
Published: (2023-12-01)
by: G. A. Burnasheva, et al.
Published: (2023-12-01)
Correlation between markers of fibrosis and myocardial remodeling in patients with various course of hypertrophic cardiomyopathy
by: F. M. Bogatyreva, et al.
Published: (2022-03-01)
by: F. M. Bogatyreva, et al.
Published: (2022-03-01)
Effects of septal myectomy on left atrial and left ventricular function in obstructive hypertrophic cardiomyopathy
by: Kyung Eun Ha, et al.
Published: (2023-10-01)
by: Kyung Eun Ha, et al.
Published: (2023-10-01)
Myocarditis in Hypertrophic Cardiomyopathy: Incidence and Contribution to Disease Progression and Outcome
by: Yulia Lutokhina, et al.
Published: (2025-04-01)
by: Yulia Lutokhina, et al.
Published: (2025-04-01)
An uncommon variant of an uncommon disease: A Caucasian adolescent with apical hypertrophic cardiomyopathy diagnosed with myocardial perfusion imaging
by: Rami Zein, et al.
Published: (2017-07-01)
by: Rami Zein, et al.
Published: (2017-07-01)
Prevalence and clinical significance of cardiovascular magnetic resonance adenosine stress-induced myocardial perfusion defect in hypertrophic cardiomyopathy
by: Eun Kyoung Kim, et al.
Published: (2020-05-01)
by: Eun Kyoung Kim, et al.
Published: (2020-05-01)
Arginine Vasopressin Plays a Role in Microvascular Dysfunction After ST‐Elevation Myocardial Infarction
by: Ayman Al‐Atta, et al.
Published: (2023-09-01)
by: Ayman Al‐Atta, et al.
Published: (2023-09-01)
Assesment of Markers of Endothelial Dysfunction and Myocardial Stress in Patients with Hypertrophic Cardyomyopathy
by: F. M. Bogatyreva, et al.
Published: (2021-07-01)
by: F. M. Bogatyreva, et al.
Published: (2021-07-01)
Early diagnosis of coronary microvascular dysfunction by myocardial contrast stress echocardiography
by: Jucheng Zhang, et al.
Published: (2023-02-01)
by: Jucheng Zhang, et al.
Published: (2023-02-01)
Exploration of Mediators Associated with Myocardial Remodelling in Feline Hypertrophic Cardiomyopathy
by: Wan-Ching Cheng, et al.
Published: (2023-06-01)
by: Wan-Ching Cheng, et al.
Published: (2023-06-01)
Effect of sarcomere and mitochondria-related mutations on myocardial fibrosis in patients with hypertrophic cardiomyopathy
by: Hyemoon Chung, et al.
Published: (2021-03-01)
by: Hyemoon Chung, et al.
Published: (2021-03-01)
Effects of Intracoronary SuperSaturated Oxygen Therapy on Myocardial Blood Flow, Microvascular Obstruction, and Myocardial Salvage in ST‐Segment–Elevation Myocardial Infarction in Swine Ischemia/Reperfusion Model
by: Pedro H. C. Melo, et al.
Published: (2025-08-01)
by: Pedro H. C. Melo, et al.
Published: (2025-08-01)
Predictive value of cardiac magnetic resonance mechanical parameters for myocardial fibrosis in hypertrophic cardiomyopathy with preserved left ventricular ejection fraction
by: Xian Hou, et al.
Published: (2022-12-01)
by: Xian Hou, et al.
Published: (2022-12-01)
Plasma ceramides as biomarkers for microvascular disease and clinical outcomes in diabetes and myocardial infarction
by: Debora Leonor Junqueira, et al.
Published: (2024-09-01)
by: Debora Leonor Junqueira, et al.
Published: (2024-09-01)
Multiple Biatrial Thromboses in a Patient with End-Stage Nonobstructive Hypertrophic Cardiomyopathy
by: Ali Hosseinsabet
Published: (2016-07-01)
by: Ali Hosseinsabet
Published: (2016-07-01)
Plasma Lipidomic Patterns in Patients with Symptomatic Coronary Microvascular Dysfunction
by: Jonathan R. Lindner, et al.
Published: (2021-09-01)
by: Jonathan R. Lindner, et al.
Published: (2021-09-01)
Non-contrast assessment of microvascular integrity using arterial spin labeled cardiovascular magnetic resonance in a porcine model of acute myocardial infarction
by: Hung P. Do, et al.
Published: (2018-07-01)
by: Hung P. Do, et al.
Published: (2018-07-01)
Wearable cardioverter-defibrillator as bridging to ICD in pediatric hypertrophic cardiomyopathy with myocardial bridging – a case report
by: Stefan Kurath-Koller, et al.
Published: (2020-05-01)
by: Stefan Kurath-Koller, et al.
Published: (2020-05-01)
Molecular imaging in hypertrophic cardiomyopathy: an exploratory study with 2-[18F]FDG and [13N]NH3
by: Maria João Ferreira, et al.
Published: (2025-02-01)
by: Maria João Ferreira, et al.
Published: (2025-02-01)
Contribution of hypoxia-inducible factor 1alpha to pathogenesis of sarcomeric hypertrophic cardiomyopathy
by: Sarala Raj Murthi, et al.
Published: (2025-01-01)
by: Sarala Raj Murthi, et al.
Published: (2025-01-01)
Similar Items
-
Cardiovascular magnetic resonance detects microvascular dysfunction in a mouse model of hypertrophic cardiomyopathy
by: Min-Chi Ku, et al.
Published: (2021-05-01) -
Assessment of myocardial work in sarcomere gene mutation carriers, healthy controls and overt nonobstructive hypertrophic cardiomyopathy
by: Carla Marques Pires, et al.
Published: (2025-02-01) -
The Impact of Ischemia Assessed by Magnetic Resonance on Functional, Arrhythmic, and Imaging Features of Hypertrophic Cardiomyopathy
by: Sílvia Aguiar Rosa, et al.
Published: (2021-12-01) -
Improvement in coronary microvascular dysfunction evaluated by cardiac magnetic resonance in patients with hypertrophic obstructive cardiomyopathy after transapical beating-heart septal myectomy
by: Yun Zhao, et al.
Published: (2023-10-01) -
Left Ventricular Noncompaction Masquerading as Hypertrophic Nonobstructive Cardiomyopathy
by: Praveen Rermal Veedu, et al.
Published: (2023-01-01)
