Comparative Description of the Expression Profile of Interferon-Stimulated Genes in Multiple Cell Lineages Targeted by HIV-1 Infection

Immediately after viral infections, innate immune sensors recognize viruses and lead to the production of type I interferon (IFN-I). IFN-I upregulates various genes, referred to as IFN-stimulated genes (ISGs), and some ISGs inhibit viral replication. HIV-1, the causative agent of AIDS, mainly infect...

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Bibliographic Details
Published in:	Frontiers in Microbiology
Main Authors:	Hirofumi Aso, Jumpei Ito, Yoshio Koyanagi, Kei Sato
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2019-03-01
Subjects:	interferon-stimulated gene type I interferon HIV-1 transcriptomics evolution bioinformatics
Online Access:	https://www.frontiersin.org/article/10.3389/fmicb.2019.00429/full

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