Quaternary Interaction of the HIV-1 Envelope Trimer with CD4 and Neutralizing Antibodies

The entry of HIV-1 into host cells is initiated by the interaction of the viral envelope (Env) spike with the CD4 receptor. During this process, the spike undergoes a series of conformational changes that eventually lead to the exposure of the fusion peptide located at the N-terminus of the transmem...

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Bibliographic Details
Published in:	Viruses
Main Authors:	Qingbo Liu, Peng Zhang, Paolo Lusso
Format:	Article
Language:	English
Published:	MDPI AG 2021-07-01
Subjects:	HIV-1 CD4 receptor binding viral entry quaternary interaction neutralizing antibodies
Online Access:	https://www.mdpi.com/1999-4915/13/7/1405

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