Botulinum Toxin-A Therapy in Pediatric Urology: Indications for the Neurogenic and Non-Neurogenic Neurogenic Bladder

Although, the role of Botulinum Toxin-A in the treatment of the neurogenic and non-neurogenic neurogenic bladder is becoming more defined, this is the first review article to characterize the emerging role of Botulinum Toxin-A in the pediatric urologic population. Injection of Botulinum Toxin-A at t...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:The Scientific World Journal
المؤلفون الرئيسيون: Lori Dyer, Israel Franco
التنسيق: مقال
اللغة:الإنجليزية
منشور في: Wiley 2009-01-01
الوصول للمادة أونلاين:http://dx.doi.org/10.1100/tsw.2009.146
الوصف
الملخص:Although, the role of Botulinum Toxin-A in the treatment of the neurogenic and non-neurogenic neurogenic bladder is becoming more defined, this is the first review article to characterize the emerging role of Botulinum Toxin-A in the pediatric urologic population. Injection of Botulinum Toxin-A at the level of the bladder works by inhibiting uninhibited bladder contractions and, possibly, by blocking some of the sensory nerve fibers. In children with sphincter dyssynergy, injection at the level of the urethral sphincter works by inhibiting the involuntary guarding reflex and blocking dyssynergic voiding.
تدمد:1537-744X