Assessment of inhalation technique in patients with bronchial asthma and chronic obstructive pulmonary disease

• Published in: Терапевтический архив
• Main Authors: Natalia V. Trushenko, Anna A. Stoliarevich, Boris G. Andriukov, Galiya S. Nuralieva, Natalya A. Tsareva, Baina B. Lavginova, Sergey N. Avdeev
• Format: Article
• Language: Russian
• Published: "Consilium Medicum" Publishing house 2023-04-01
• Subjects: inhaler technique; metered dose inhalers; dry powder inhalers; errors; aerosols; asthma; chronic obstructive pulmonary disease; copd
• Online Access: https://ter-arkhiv.ru/0040-3660/article/viewFile/62490/pdf
• ISSN: 0040-3660; 2309-5342

Aim. Investigate inhalation techniques using different inhalers types and their effect on the course of disease. Materials and methods. This cross-sectional study included 110 patients with asthma, chronic obstructive pulmonary disease using the inhaler at least one month. Inhaler errors performed during demonstration were evaluated for each patient and entered in the check-lists. We also collected information about co-morbidities, education, mMRC dyspnea score, rate of exacerbations, and performed spirometry. Results. 80.9% of patients used metered-dose inhaler, 20.9% single-dose and 21.8% multiple-dose dry powder inhaler, 22.7% soft-mist inhaler. Inhaler errors were made by 80.9% patients. The mean number of mistakes in metered-dose inhaler use was 21.6, single-dose powder inhaler 1.51.3, multiple-dose dry powder inhaler 1.251.4, soft-mist inhaler 0.680.7 (р=0.003). Age, diagnosis, duration of disease, education level, inhalers usage by relatives have no influence on the inhalation technique. A number of errors was related to female gender (р=0.007) and usage of more than 2 inhalers (r=0.3, p=0.002), previous instruction about inhalation technique (r=0.3, p=0.001). On the other hand, there were correlations between the number of errors and degree of bronchial obstruction, asthma control, severity of dyspnea by mMRC score, exacerbation rate. Conclusion. Patients with bronchoobstructive diseases perform many inhaler errors, that substantially influences the severity and course of asthma and chronic obstructive pulmonary disease.