The Role of Angiogenesis in Colorectal Polyps and Cancer, a Review

ABSTRACT           Colorectal cancer remains a leading cause of morbidity and mortality worldwide. Most colorectal cancers begin as a growth of tissue called a polyp, some types of which can change into cancer over the course of several years. Angiogenesis, the formation of new blood vessels, is kno...

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Bibliographic Details
Published in:Medical Laboratory Journal
Main Authors: Hamid Asadzadeh Aghdaei, Zahra Pezeshkian, Meghdad Abdollahpour-Alitappeh, Ehsan Nazemalhosseini Mojarad, Mohammad Reza Zali
Format: Article
Language:English
Published: Golestan University of Medical Sciences 2018-07-01
Subjects:
colorectal neoplasms
polyps
angiogenesis
Online Access:http://mlj.goums.ac.ir/article-1-1093-en.html
Description
Summary:ABSTRACT           Colorectal cancer remains a leading cause of morbidity and mortality worldwide. Most colorectal cancers begin as a growth of tissue called a polyp, some types of which can change into cancer over the course of several years. Angiogenesis, the formation of new blood vessels, is known to play a key role in the initiation, growth and progression of polyp and colorectal cancer. In this review, we discuss the mechanisms involved in colorectal cancer and polyp angiogenesis.           Keywords: Colorectal Neoplasms, Polyps, Angiogenesis
ISSN:2538-4449

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