Obstructive Jaundice Secondary to Pancreatic Head Metastasis of Malignant Amelanotic Melanoma as the First Clinical Manifestation

Malignant melanoma is commonly known for its high probability of metastasizing to distant organs. Metastases to gastrointestinal tract are well documented, but resulting jaundice is only scarcely seen. We present a case of histologically verified metastasis of amelanotic melanoma to the head of panc...

Full description

Bibliographic Details
Published in:Prague Medical Report
Main Authors: Jan Zeman, Lucie Olivová, Jan Hrudka, Jan Hajer, Ivan Rychlík
Format: Article
Language:English
Published: Karolinum Press 2021-03-01
Subjects:
obstructive jaundice
malignant melanoma
pancreatic metastasis
braf genes
Online Access:https://pmr.lf1.cuni.cz/122/1/0045/
Description
Summary:Malignant melanoma is commonly known for its high probability of metastasizing to distant organs. Metastases to gastrointestinal tract are well documented, but resulting jaundice is only scarcely seen. We present a case of histologically verified metastasis of amelanotic melanoma to the head of pancreas infiltrating the common bile duct and consequently causing obstructive jaundice which constituted its first clinical manifestation. Multidisciplinary approach is essential in patients with malignant melanoma since early detection of the melanoma or its metastases may improve patients’ clinical outcome, especially owing to the use of targeted biological treatment without any delay.
ISSN:1214-6994
2336-2936

Similar Items