Point-of-care testing of nitrite in oral medicine - Application and validation of an enzymatic biosensor in human saliva
Periodontal disease (PD) is a chronic inflammatory condition triggered by bacterial biofilms and progresses through two main stages: gingivitis and periodontitis. The existing diagnostic methods remain time-consuming and require clinical expertise. Salivary nitrite, a stable end-product of nitric ox...
| Published in: | Sensing and Bio-Sensing Research |
|---|---|
| Main Authors: | Sara Rodrigues Gaspar, Luís Proença, Ricardo Alves, Maria Gabriela Almeida |
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-08-01
|
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2214180425001266 |
Similar Items
Nitrite Biosensing via Selective Enzymes—A Long but Promising Route
by: M. Gabriela Almeida, et al.
Published: (2010-12-01)
by: M. Gabriela Almeida, et al.
Published: (2010-12-01)
Total Nitrite and Nitrate Concentration in Human Milk and Saliva during the First 60 Days Postpartum—A Pilot Study
by: Jenny Ericson, et al.
Published: (2024-05-01)
by: Jenny Ericson, et al.
Published: (2024-05-01)
Ion Selective Amperometric Biosensors for Environmental Analysis of Nitrate, Nitrite and Sulfate
by: Niels Peter Revsbech, et al.
Published: (2020-08-01)
by: Niels Peter Revsbech, et al.
Published: (2020-08-01)
Reusable Biosensor for Easy RNA Detection from Unfiltered Saliva
by: Paweł Wityk, et al.
Published: (2025-01-01)
by: Paweł Wityk, et al.
Published: (2025-01-01)
Modified Glass Carbon Electrode (GCE) Electropolymerized Polypyrrole Nanofibers with Hemoglobin (Hb) Film as a Unique Biosensor for Nitrite Determination
by: mohamad Ali zare
Published: (2020-05-01)
by: mohamad Ali zare
Published: (2020-05-01)
Advancements and Trends in Electrochemical Biosensors for Saliva-Based Diagnosis of Oral Diseases: A Bibliometric Analysis (2000–2023)
by: Qian Tang, et al.
Published: (2025-08-01)
by: Qian Tang, et al.
Published: (2025-08-01)
Bio-Doped Microbial Nanosilica as Optosensing Biomaterial for Visual Quantitation of Nitrite in Cured Meats
by: Siti Nur Syazni Mohd Zuki, et al.
Published: (2022-06-01)
by: Siti Nur Syazni Mohd Zuki, et al.
Published: (2022-06-01)
Nitrite and Nitrate Levels of Gingival Crevicular Fluid and Saliva in Subjects with Gingivitis and Chronic Periodontitis
by: Ali Orkun Topcu, et al.
Published: (2014-07-01)
by: Ali Orkun Topcu, et al.
Published: (2014-07-01)
The validation of urea determination in saliva using optical urea biosensor with p-dimethylaminobenzaldehyde (DMAB) reagent
by: TEUKU ALDIANSYAH, et al.
Published: (2025-03-01)
by: TEUKU ALDIANSYAH, et al.
Published: (2025-03-01)
Point-of-Care Detection of Salivary Nitrite Based on the Surface Plasmon-Assisted Catalytic Coupling Reaction of Aromatic Amines
by: Chen Zhao, et al.
Published: (2021-07-01)
by: Chen Zhao, et al.
Published: (2021-07-01)
Malignancies and Biosensors: A Focus on Oral Cancer Detection through Salivary Biomarkers
by: Riccardo Goldoni, et al.
Published: (2021-10-01)
by: Riccardo Goldoni, et al.
Published: (2021-10-01)
Ascorbate mediates the non-enzymatic reduction of nitrite to nitric oxide
by: Juan Du, et al.
Published: (2023-12-01)
by: Juan Du, et al.
Published: (2023-12-01)
Emerging Biosensors for Oral Cancer Detection and Diagnosis—A Review Unravelling Their Role in Past and Present Advancements in the Field of Early Diagnosis
by: Vidhya Rekha Umapathy, et al.
Published: (2022-07-01)
by: Vidhya Rekha Umapathy, et al.
Published: (2022-07-01)
Cascading chemiresistive paper-based enzymatic biosensor for urea detection
by: Ronil J. Rath, et al.
Published: (2025-06-01)
by: Ronil J. Rath, et al.
Published: (2025-06-01)
sIgA, peroxidase and collagenase in saliva of smokers aggressive periodontal patients
by: Myriam A. Koss, et al.
Published: (2016-11-01)
by: Myriam A. Koss, et al.
Published: (2016-11-01)
Free Ammonia Strategy for Nitrite-Oxidizing Bacteria (NOB) Suppression in Mainstream Nitritation Start-Up
by: Soyeon Jeong, et al.
Published: (2024-09-01)
by: Soyeon Jeong, et al.
Published: (2024-09-01)
Label‐Free Metal‐Oxide Transistor Biosensors for Metabolite Detection in Human Saliva
by: Abhinav Sharma, et al.
Published: (2024-07-01)
by: Abhinav Sharma, et al.
Published: (2024-07-01)
Kinetic Analysis of Nitrite Reduction Reactions by Nitrite Reductase Derived from Spinach in the Presence of One-Electron Reduced Riboflavin
by: Shusaku Ikeyama, et al.
Published: (2022-03-01)
by: Shusaku Ikeyama, et al.
Published: (2022-03-01)
From Biomarkers to Biosensors: Modern Approaches for the Detection of Matrix Metalloproteinases (MMPs)
by: Raja Chinnappan, et al.
Published: (2025-09-01)
by: Raja Chinnappan, et al.
Published: (2025-09-01)
Saliva Microbiome Changes in Patients With Periodontitis With and Without Chronic Obstructive Pulmonary Disease
by: Mei Lin, et al.
Published: (2020-04-01)
by: Mei Lin, et al.
Published: (2020-04-01)
Analysis of Microbial Diversity Dominating Nitrite Enzymatic Degradation and Acidic Degradation in the Fermentation Broth of Northeast Sauerkraut
by: Xiangru Xu, et al.
Published: (2024-12-01)
by: Xiangru Xu, et al.
Published: (2024-12-01)
Metaproteomics of saliva identifies human protein markers specific for individuals with periodontitis and dental caries compared to orally healthy controls
by: Daniel Belstrøm, et al.
Published: (2016-09-01)
by: Daniel Belstrøm, et al.
Published: (2016-09-01)
Transcriptomic and enzymatic analyses revealed synergistic toxicity of ammonia and nitrite on Ruditapes philipparum
by: Ming Cong, et al.
Published: (2025-08-01)
by: Ming Cong, et al.
Published: (2025-08-01)
Awareness about the significance of acid–base balance of saliva in maintaining oral health
by: Charanya Suresh, et al.
Published: (2022-01-01)
by: Charanya Suresh, et al.
Published: (2022-01-01)
Intraoral biosensors: A promising diagnostic tool
by: Shefali Dogra, et al.
Published: (2022-01-01)
by: Shefali Dogra, et al.
Published: (2022-01-01)
Oral Diagnostic Methods for the Detection of Periodontal Disease
by: Liza L. Ramenzoni, et al.
Published: (2021-03-01)
by: Liza L. Ramenzoni, et al.
Published: (2021-03-01)
A Novel Nitrite Reductase from <i>Acinetobacter haemolyticus</i> for Efficient Degradation of Nitrite
by: Xiao-Yan Yin, et al.
Published: (2025-01-01)
by: Xiao-Yan Yin, et al.
Published: (2025-01-01)
Assessing Popper Purity—Implications for the Regulation and Recreational Use of Alkyl Nitrites
by: Nathan S. Makarewicz, et al.
Published: (2024-09-01)
by: Nathan S. Makarewicz, et al.
Published: (2024-09-01)
Is There a Difference in the Proteomic Profile of Stimulated and Unstimulated Saliva Samples from Pregnant Women with/without Obesity and Periodontitis?
by: Gerson Aparecido Foratori-Junior, et al.
Published: (2023-05-01)
by: Gerson Aparecido Foratori-Junior, et al.
Published: (2023-05-01)
Saliva as a diagnostic tool for evaluating oxidative stress in periodontitis and its correlation with tobacco habits: A cross sectional study
by: Margee Desai Sharma, et al.
Published: (2018-01-01)
by: Margee Desai Sharma, et al.
Published: (2018-01-01)
Nitrate and nitrite reductase activities of Mycobacterium avium
by: Nitin S Butala, et al.
Published: (2018-01-01)
by: Nitin S Butala, et al.
Published: (2018-01-01)
Advancing Point-of-Care (PoC) Testing Using Human Saliva as Liquid Biopsy
by: Rabia Sannam Khan, et al.
Published: (2017-07-01)
by: Rabia Sannam Khan, et al.
Published: (2017-07-01)
Nitrites Variation in Cheese depending on their Concentration in Milk
by: Cornelia Vintilă, et al.
Published: (2023-10-01)
by: Cornelia Vintilă, et al.
Published: (2023-10-01)
Saliva as a Diagnostic Tool for Systemic Diseases—A Narrative Review
by: Amelia Surdu, et al.
Published: (2025-01-01)
by: Amelia Surdu, et al.
Published: (2025-01-01)
Dental risk factors associated with oral Helicobacter pylori infection: a cross-sectional study based on saliva antigen test
by: Dhary Alewy Almashhadany, et al.
Published: (2022-03-01)
by: Dhary Alewy Almashhadany, et al.
Published: (2022-03-01)
New Biosensor for Determination of Neuropilin-1 with Detection by Surface Plasmon Resonance Imaging
by: Anna Sankiewicz, et al.
Published: (2023-04-01)
by: Anna Sankiewicz, et al.
Published: (2023-04-01)
Indirect Antioxidant Effects of the Nitrite Anion: Focus on Xanthine Oxidase
by: Xena M. Williams, et al.
Published: (2023-04-01)
by: Xena M. Williams, et al.
Published: (2023-04-01)
Assessment of IL-8 levels in saliva of healthy and chronic periodontitis individuals
by: Vinaykumar G Suryavanshi, et al.
Published: (2024-01-01)
by: Vinaykumar G Suryavanshi, et al.
Published: (2024-01-01)
Low-cost ultrasensitive flexible carbon fiber-based biosensor for the detection of SARS-CoV-2 in human saliva
by: Steffane Q. Nascimento, et al.
Published: (2024-06-01)
by: Steffane Q. Nascimento, et al.
Published: (2024-06-01)
Filtered Saliva for Rapid and Accurate Analyte Detection for POC Diagnostics
by: Nadia Farsaeivahid, et al.
Published: (2024-05-01)
by: Nadia Farsaeivahid, et al.
Published: (2024-05-01)
Similar Items
-
Nitrite Biosensing via Selective Enzymes—A Long but Promising Route
by: M. Gabriela Almeida, et al.
Published: (2010-12-01) -
Total Nitrite and Nitrate Concentration in Human Milk and Saliva during the First 60 Days Postpartum—A Pilot Study
by: Jenny Ericson, et al.
Published: (2024-05-01) -
Ion Selective Amperometric Biosensors for Environmental Analysis of Nitrate, Nitrite and Sulfate
by: Niels Peter Revsbech, et al.
Published: (2020-08-01) -
Reusable Biosensor for Easy RNA Detection from Unfiltered Saliva
by: Paweł Wityk, et al.
Published: (2025-01-01) -
Modified Glass Carbon Electrode (GCE) Electropolymerized Polypyrrole Nanofibers with Hemoglobin (Hb) Film as a Unique Biosensor for Nitrite Determination
by: mohamad Ali zare
Published: (2020-05-01)
