Molecular Mechanisms of the Anti-Cancer Effects of Isothiocyanates from Cruciferous Vegetables in Bladder Cancer
Bladder cancer (BC) is a representative of urological cancer with a high recurrence and metastasis potential. Currently, cisplatin-based chemotherapy and immune checkpoint inhibitors are used as standard therapy in patients with advanced/metastatic BC. However, these therapies often show severe adve...
| Published in: | Molecules |
|---|---|
| Main Authors: | Tomhiro Mastuo, Yasuyoshi Miyata, Tsutomu Yuno, Yuta Mukae, Asato Otsubo, Kensuke Mitsunari, Kojiro Ohba, Hideki Sakai |
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2020-01-01
|
| Subjects: | |
| Online Access: | https://www.mdpi.com/1420-3049/25/3/575 |
Similar Items
An Evaluation of the Anti-Carcinogenic Response of Major Isothiocyanates in Non-Metastatic and Metastatic Melanoma Cells
by: Melina Mitsiogianni, et al.
Published: (2021-02-01)
by: Melina Mitsiogianni, et al.
Published: (2021-02-01)
Metformin and phenethyl isothiocyanate combined treatment <it>in vitro</it> is cytotoxic to ovarian cancer cultures
by: Chan Daniel K, et al.
Published: (2012-07-01)
by: Chan Daniel K, et al.
Published: (2012-07-01)
Effects of Four Isothiocyanates in Dissolved and Gaseous States on the Growth and Aflatoxin Production of <i>Aspergillus flavus</i> In Vitro
by: Yohei Hareyama, et al.
Published: (2022-11-01)
by: Yohei Hareyama, et al.
Published: (2022-11-01)
Allyl isothiocyanate affects the cell cycle of Arabidopsis thaliana
by: Signe Elisabeth Åsberg, et al.
Published: (2015-05-01)
by: Signe Elisabeth Åsberg, et al.
Published: (2015-05-01)
Naturally Derived Phenethyl Isothiocyanate Modulates Induction of Oxidative Stress via Its <i>N</i>-Acetylated Cysteine Conjugated form in Malignant Melanoma
by: Sotiris Kyriakou, et al.
Published: (2024-01-01)
by: Sotiris Kyriakou, et al.
Published: (2024-01-01)
Impact of non-thermal plasma seed priming and early development stages of two local Thai Cruciferous plants mustard green and rat-tailed radish on glucosinolates, isothiocyanates, minerals, antioxidant and anticancer activities
by: Thipphiya KARIRAT, et al.
Published: (2025-02-01)
by: Thipphiya KARIRAT, et al.
Published: (2025-02-01)
Sulforaphene and sulforaphane in commonly consumed cruciferous plants contributed to antiproliferation in HCT116 colon cancer cells
by: Piman Pocasap, et al.
Published: (2016-02-01)
by: Piman Pocasap, et al.
Published: (2016-02-01)
Cooking Methods for Preserving Isothiocyanates and Reducing Goitrin in <i>Brassica</i> Vegetables
by: Thanaporn Panduang, et al.
Published: (2023-10-01)
by: Thanaporn Panduang, et al.
Published: (2023-10-01)
Differentiated Effects of Allyl Isothiocyanate in Diabetic Rats: From Toxic to Beneficial Action
by: Monika Okulicz, et al.
Published: (2021-12-01)
by: Monika Okulicz, et al.
Published: (2021-12-01)
THE EFFECT PRODUCED BY SYNTHETICALLY AND NATURALLY ALLYL ISOTHIOCYANATE ON SEEDLING GROWTH OF TWO WHEAT VARIETIES
by: Șipoș Monica, et al.
Published: (2023-05-01)
by: Șipoș Monica, et al.
Published: (2023-05-01)
A Review of Propagation Techniques and Isothiocyanates Content in Wasabi (Wasabia japonica Matsum.)
by: Věra Kofránková, et al.
Published: (2019-01-01)
by: Věra Kofránková, et al.
Published: (2019-01-01)
A Lesson Learnt from Food Chemistry—Elevated Temperature Triggers the Antioxidant Action of Two Edible Isothiocyanates: Erucin and Sulforaphane
by: Jakub Cedrowski, et al.
Published: (2020-11-01)
by: Jakub Cedrowski, et al.
Published: (2020-11-01)
Synergistic Interaction between 5-FU and an Analog of Sulforaphane—2-Oxohexyl Isothiocyanate—In an In Vitro Colon Cancer Model
by: Małgorzata Milczarek, et al.
Published: (2021-05-01)
by: Małgorzata Milczarek, et al.
Published: (2021-05-01)
Preplant Application of Allyl Isothiocyanate Controls Weeds and Pathogens in Eastern North Carolina Strawberry (Fragaria ×ananassa cv. Camarosa) with and without Addition of Soil-applied Steam
by: Emma Volk, et al.
Published: (2023-09-01)
by: Emma Volk, et al.
Published: (2023-09-01)
The Reaction of Allyl Isothiocyanate with Hydroxyl/Water and β-Cyclodextrin Using Ultraviolet Spectrometry
by: Zi-Tao Jiang, et al.
Published: (2006-01-01)
by: Zi-Tao Jiang, et al.
Published: (2006-01-01)
Bioavailability, Human Metabolism, and Dietary Interventions of Glucosinolates and Isothiocyanates: Critical Insights and Future Perspectives
by: Federica Narra, et al.
Published: (2025-08-01)
by: Federica Narra, et al.
Published: (2025-08-01)
Effect of a carrageenan/chitosan coating with allyl isothiocyanate on microbial spoilage and quality of chicken breast
by: Amanda Moller, et al.
Published: (2023-03-01)
by: Amanda Moller, et al.
Published: (2023-03-01)
Contents of sulforaphane and total isothiocyanates, antimutagenic activity, and inhibition of clastogenicity in pulp
by: Jiří Totušek, et al.
Published: (2011-10-01)
by: Jiří Totušek, et al.
Published: (2011-10-01)
Effects of Allyl Isothiocyanate on Oxidative and Inflammatory Stress in Type 2 Diabetic Rats
by: Monika Okulicz, et al.
Published: (2022-08-01)
by: Monika Okulicz, et al.
Published: (2022-08-01)
Anti‐pruritic effect of isothiocyanates: Potential involvement of toll‐like receptor 3 signaling
by: Masaki Moriyama, et al.
Published: (2022-12-01)
by: Masaki Moriyama, et al.
Published: (2022-12-01)
Anticancer Activity, Mechanism, and Delivery of Allyl Isothiocyanate
by: Ammar Tarar, et al.
Published: (2022-09-01)
by: Ammar Tarar, et al.
Published: (2022-09-01)
Dietary isothiocyanates and anticancer agents: exploring synergism for improved cancer management
by: Qi Wang, et al.
Published: (2024-06-01)
by: Qi Wang, et al.
Published: (2024-06-01)
Turning glucosinolate into allelopathic fate: investigating allyl isothiocyanate variability and nitrile formation in eco-friendly Brassica juncea from South Korea
by: Da-Yeong Ko, et al.
Published: (2024-07-01)
by: Da-Yeong Ko, et al.
Published: (2024-07-01)
Myrosinase-dependent and –independent formation and control of isothiocyanate products of glucosinolate hydrolysis.
by: Donato eAngelino, et al.
Published: (2015-10-01)
by: Donato eAngelino, et al.
Published: (2015-10-01)
Cell Death Effects Induced by Sulforaphane and Allyl Isothiocyanate on P-Glycoprotein Positive and Negative Variants in L1210 Cells
by: Szilvia Kontar, et al.
Published: (2020-04-01)
by: Szilvia Kontar, et al.
Published: (2020-04-01)
Anticancer activity of sulforaphane against human hepatoblastoma cells involves apoptosis, autophagy and inhibition of β-catenin signaling pathway
by: Junshan Lin, et al.
Published: (2020-06-01)
by: Junshan Lin, et al.
Published: (2020-06-01)
Inhibitory Effect of Phenethyl Isothiocyanate on the Adhesion and Biofilm Formation of <i>Staphylococcus aureus</i> and Application on Beef
by: Xiaojing Ma, et al.
Published: (2024-10-01)
by: Xiaojing Ma, et al.
Published: (2024-10-01)
Effect of allyl isothiocyanate on developmental toxicity in exposed Xenopus laevis embryos
by: John Russell Williams, et al.
Published: (2015-01-01)
by: John Russell Williams, et al.
Published: (2015-01-01)
Health Benefits, Applications, and Analytical Methods of Freshly Produced Allyl Isothiocyanate
by: Walaa Alibrahem, et al.
Published: (2025-02-01)
by: Walaa Alibrahem, et al.
Published: (2025-02-01)
Comparative Studies of Extracts Obtained from <i>Brassica oleracea</i> L. Plants at Different Stages of Growth by Isolation and Determination of Isothiocyanates: An Assessment of Chemopreventive Properties of Broccoli
by: Magdalena Ligor, et al.
Published: (2024-01-01)
by: Magdalena Ligor, et al.
Published: (2024-01-01)
Preparation of Eugenol–Thymol–Cuminal Composite Essential Oil Microcapsules with AITC & β-Cyclodextrin Inclusion Complex and Its Effect on Quality of Chilled Pork
by: Wenxiao Li, et al.
Published: (2025-03-01)
by: Wenxiao Li, et al.
Published: (2025-03-01)
Effect of Prooxidative Natural Products: Comparison of the OSI1 (YKL071w) Promoter Luciferase Construct from Yeast with an Nrf2/Keap Reporter System
by: Ivan Schlembach, et al.
Published: (2020-05-01)
by: Ivan Schlembach, et al.
Published: (2020-05-01)
Evaluation of Bioactive Properties of Lipophilic Fractions of Edible and Non-Edible Parts of <i>Nasturtium officinale</i> (Watercress) in a Model of Human Malignant Melanoma Cells
by: Sotiris Kyriakou, et al.
Published: (2022-01-01)
by: Sotiris Kyriakou, et al.
Published: (2022-01-01)
Anticancer properties of sulforaphane: current insights at the molecular level
by: Muhammad Asif Ali, et al.
Published: (2023-06-01)
by: Muhammad Asif Ali, et al.
Published: (2023-06-01)
Efficacy and tolerability of sulforaphane in the therapeutic management of cancers: a systematic review of randomized controlled trials
by: Dana ElKhalifa, et al.
Published: (2023-11-01)
by: Dana ElKhalifa, et al.
Published: (2023-11-01)
Antifungal activity of Allyl isothiocyanate by targeting signal transduction pathway, ergosterol biosynthesis, and cell cycle in Candida albicans
by: Shivani Patil, et al.
Published: (2023-06-01)
by: Shivani Patil, et al.
Published: (2023-06-01)
Sulforaphane and Its Bifunctional Analogs: Synthesis and Biological Activity
by: Łukasz Janczewski
Published: (2022-03-01)
by: Łukasz Janczewski
Published: (2022-03-01)
Phenethyl isothiocyanate as an anti-nutritional factor attenuates deoxynivalenol-induced IPEC-J2 cell injury through inhibiting ROS-mediated autophagy
by: Shuiping Liu, et al.
Published: (2022-03-01)
by: Shuiping Liu, et al.
Published: (2022-03-01)
Inhibitory effects of benzyl isothiocyanate on widespread mcr-1-harbouring IncX4 plasmid transfer
by: Sirirat Luk-In, et al.
Published: (2025-04-01)
by: Sirirat Luk-In, et al.
Published: (2025-04-01)
Phenethyl Isothiocyanate-Containing Carbomer Gel for Use against Squamous Cell Carcinoma
by: Ositomiwa O. Osipitan, et al.
Published: (2021-01-01)
by: Ositomiwa O. Osipitan, et al.
Published: (2021-01-01)
Similar Items
-
An Evaluation of the Anti-Carcinogenic Response of Major Isothiocyanates in Non-Metastatic and Metastatic Melanoma Cells
by: Melina Mitsiogianni, et al.
Published: (2021-02-01) -
Metformin and phenethyl isothiocyanate combined treatment <it>in vitro</it> is cytotoxic to ovarian cancer cultures
by: Chan Daniel K, et al.
Published: (2012-07-01) -
Effects of Four Isothiocyanates in Dissolved and Gaseous States on the Growth and Aflatoxin Production of <i>Aspergillus flavus</i> In Vitro
by: Yohei Hareyama, et al.
Published: (2022-11-01) -
Allyl isothiocyanate affects the cell cycle of Arabidopsis thaliana
by: Signe Elisabeth Åsberg, et al.
Published: (2015-05-01) -
Naturally Derived Phenethyl Isothiocyanate Modulates Induction of Oxidative Stress via Its <i>N</i>-Acetylated Cysteine Conjugated form in Malignant Melanoma
by: Sotiris Kyriakou, et al.
Published: (2024-01-01)
