State-of-the-art for CAR T-cell therapy for chronic lymphocytic leukemia in 2019
Abstract Experience in the use of CAR T cells to treat CLL is limited, but safety and efficacy data are encouraging, suggesting that it may be possible to use CAR T cells in populations of CLL patients with particularly unfavorable prognoses. Mechanisms intrinsic to the pathophysiology of CLL undoub...
| Published in: | Journal for ImmunoTherapy of Cancer |
|---|---|
| Main Authors: | Richard Lemal, Olivier Tournilhac |
| Format: | Article |
| Language: | English |
| Published: |
BMJ Publishing Group
2019-08-01
|
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s40425-019-0686-x |
Similar Items
CAR T Cell Therapy for Chronic Lymphocytic Leukemia: Successes and Shortcomings
by: Zeljko Todorovic, et al.
Published: (2022-05-01)
by: Zeljko Todorovic, et al.
Published: (2022-05-01)
Preclinical evaluation of combination nemtabrutinib and venetoclax in chronic lymphocytic leukemia
by: Elizabeth M. Muhowski, et al.
Published: (2022-11-01)
by: Elizabeth M. Muhowski, et al.
Published: (2022-11-01)
The regulation of tumor‐suppressive microRNA, miR‐126, in chronic lymphocytic leukemia
by: Daphne Guinn, et al.
Published: (2017-04-01)
by: Daphne Guinn, et al.
Published: (2017-04-01)
Pharmacists’ Role in Managing Patients with Chronic Lymphocytic Leukemia
by: Kevin Y. Chen, et al.
Published: (2020-03-01)
by: Kevin Y. Chen, et al.
Published: (2020-03-01)
Ibrutinib-Induced Cardiac Tamponade in Chronic Lymphocytic Leukemia
by: Keisuke Kidoguchi, et al.
Published: (2021-02-01)
by: Keisuke Kidoguchi, et al.
Published: (2021-02-01)
Search for Synergistic Drug Combinations to Treat Chronic Lymphocytic Leukemia
by: Eleonora Ela Hezkiy, et al.
Published: (2022-11-01)
by: Eleonora Ela Hezkiy, et al.
Published: (2022-11-01)
Comparison of the blood immune repertoire with clinical features in chronic lymphocytic leukemia patients treated with chemoimmunotherapy or ibrutinib
by: Baustin M. Welch, et al.
Published: (2023-12-01)
by: Baustin M. Welch, et al.
Published: (2023-12-01)
CAR-T CELLS IN CHRONIC LYMPHOCYTIC LEUKEMIA
by: Ugo Testa, et al.
Published: (2024-04-01)
by: Ugo Testa, et al.
Published: (2024-04-01)
SUCCESSFUL LONG-TERM REMISSION IN AGGRESSIVE YOUNG-ONSET CHRONIC LYMPHOCYTIC LEUKEMIA WITH IBRUTINIB AND VENETOCLAX: A DECADE-LONG CASE STUDY
by: Naciye Nur Tozluklu, et al.
Published: (2024-12-01)
by: Naciye Nur Tozluklu, et al.
Published: (2024-12-01)
An unusual case of chronic lymphocytic leukemia with trisomy 12 and t(14;18) and a favorable response to ibrutinib
by: Fady Gh Haddad, et al.
Published: (2021-01-01)
by: Fady Gh Haddad, et al.
Published: (2021-01-01)
Healthcare cost comparison between first-line ibrutinib and acalabrutinib in chronic lymphocytic leukemia patients in the Veterans Affairs
by: Lindsey Fitzgerald, et al.
Published: (2025-10-01)
by: Lindsey Fitzgerald, et al.
Published: (2025-10-01)
Ibrutinib-Induced Skin Rash
by: Sudhir Kirar, et al.
Published: (2021-02-01)
by: Sudhir Kirar, et al.
Published: (2021-02-01)
Possibilities of therapy recurrent b-cell chronic lymphocytic leukemia associated with autoimmune complications: data from literature and personal observation
by: S. R. Goryacheva, et al.
Published: (2018-07-01)
by: S. R. Goryacheva, et al.
Published: (2018-07-01)
A real‐world study to assess the association of cardiovascular adverse events (CVAEs) with ibrutinib as first‐line (1L) treatment for patients with chronic lymphocytic leukaemia (CLL) in the United States
by: Anthony Mato, et al.
Published: (2023-02-01)
by: Anthony Mato, et al.
Published: (2023-02-01)
Optimization of anti-CD19 CAR T cell production for treatment of patients with chronic lymphocytic leukemia
by: Christina Amatya, et al.
Published: (2024-03-01)
by: Christina Amatya, et al.
Published: (2024-03-01)
Ibrutinib in the Treatment of Refractory Chronic Lymphocytic Leukemia
by: EA Nikitin, et al.
Published: (2017-07-01)
by: EA Nikitin, et al.
Published: (2017-07-01)
Management of infections for patient treated with ibrutinib in clinical practice
by: Claudia Baratè, et al.
Published: (2024-09-01)
by: Claudia Baratè, et al.
Published: (2024-09-01)
The Role of BTK Inhibition in the Treatment of Chronic Lymphocytic Leukemia: A Clinical View
by: Tambaro FP, et al.
Published: (2021-10-01)
by: Tambaro FP, et al.
Published: (2021-10-01)
Venetoclax inhibits autophagy in chronic lymphocytic leukemia cells
by: Yongqiang Chen, et al.
Published: (2023-12-01)
by: Yongqiang Chen, et al.
Published: (2023-12-01)
Research progress in targeted therapies of chronic lymphocytic leukemia
by: DING Yanling, et al.
Published: (2024-02-01)
by: DING Yanling, et al.
Published: (2024-02-01)
Real-World Clinical Outcomes and Adverse Events in Patients with Chronic Lymphocytic Leukemia Treated with Ibrutinib: A Single-Center Retrospective Study
by: Ana-Maria Moldovianu, et al.
Published: (2023-02-01)
by: Ana-Maria Moldovianu, et al.
Published: (2023-02-01)
Impact of mitochondrial metabolism on T-cell dysfunction in chronic lymphocytic leukemia
by: Wael Gamal, et al.
Published: (2025-04-01)
by: Wael Gamal, et al.
Published: (2025-04-01)
Long-Term Ibrutinib Therapy Reverses CD8+ T Cell Exhaustion in B Cell Chronic Lymphocytic Leukaemia
by: Helen M. Parry, et al.
Published: (2019-12-01)
by: Helen M. Parry, et al.
Published: (2019-12-01)
Efficacy and safety of CAR-T therapy targeting CLL1 in patients with extramedullary diseases of acute myeloid leukemia
by: Yifan Zhao, et al.
Published: (2024-10-01)
by: Yifan Zhao, et al.
Published: (2024-10-01)
Preclinical investigations of the efficacy of the glutaminase inhibitor CB-839 alone and in combinations in chronic lymphocytic leukemia
by: Natalia Timofeeva, et al.
Published: (2023-05-01)
by: Natalia Timofeeva, et al.
Published: (2023-05-01)
Ibrutinib-induced cardiomyopathy
by: Htay Htay Kyi, et al.
Published: (2019-01-01)
by: Htay Htay Kyi, et al.
Published: (2019-01-01)
Ibrutinib-Associated Leukocytoclastic Vasculitis in a Patient with Chronic Lymphocytic Leukemia
by: Ayşe Kaya, et al.
Published: (2024-03-01)
by: Ayşe Kaya, et al.
Published: (2024-03-01)
Linking SLAMF1 to autophagy and sensitivity to therapy in chronic lymphocytic leukemia
by: Cinzia Bologna, et al.
Published: (2018-05-01)
by: Cinzia Bologna, et al.
Published: (2018-05-01)
Successful Anti-CLL1 CAR T-Cell Therapy in Secondary Acute Myeloid Leukemia
by: Hui Zhang, et al.
Published: (2020-05-01)
by: Hui Zhang, et al.
Published: (2020-05-01)
Therapeutic Management of Chronic Lymphocytic Leukemia Presenting with Recurrent Massive Ascites
by: Ugochi Ebinama, et al.
Published: (2022-09-01)
by: Ugochi Ebinama, et al.
Published: (2022-09-01)
Utilization of donor CLL-1 CAR-T cells for the treatment of relapsed of acute myeloid leukemia following allogeneic hematopoietic stem cell transplantation
by: Meng Zhang, et al.
Published: (2025-01-01)
by: Meng Zhang, et al.
Published: (2025-01-01)
Modified CD15/CD16-CLL1 inhibitory CAR-T cells for mitigating granulocytopenia toxicities in the treatment of acute myeloid leukemia
by: Rui Zhang, et al.
Published: (2025-02-01)
by: Rui Zhang, et al.
Published: (2025-02-01)
Concurrent hyperdiploid acute myeloid leukemia and trisomy 12+ chronic lymphocytic leukemia
by: Tulasi Geevar, et al.
Published: (2024-10-01)
by: Tulasi Geevar, et al.
Published: (2024-10-01)
Occurrence of chronic lymphocytic leukemia in patients with chronic myelogenous leukemia
by: Pritish K Bhattacharyya
Published: (2013-01-01)
by: Pritish K Bhattacharyya
Published: (2013-01-01)
Cellular Therapy in High-Risk Relapsed/Refractory Chronic Lymphocytic Leukemia and Richter Syndrome
by: Maria Chiara Barbanti, et al.
Published: (2022-04-01)
by: Maria Chiara Barbanti, et al.
Published: (2022-04-01)
Current state of NK cell-mediated immunotherapy in chronic lymphocytic leukemia
by: Zong-Han Wang, et al.
Published: (2023-01-01)
by: Zong-Han Wang, et al.
Published: (2023-01-01)
Broadening the horizon: potential applications of CAR-T cells beyond current indications
by: Hendrik Karsten, et al.
Published: (2023-11-01)
by: Hendrik Karsten, et al.
Published: (2023-11-01)
Macrophage Polarization in Chronic Lymphocytic Leukemia: Nurse-Like Cells Are the Caretakers of Leukemic Cells
by: Oana Mesaros, et al.
Published: (2020-11-01)
by: Oana Mesaros, et al.
Published: (2020-11-01)
Strategies to overcome CAR-T cell resistance in clinical work: A single-institute experience
by: Feifei Nan, et al.
Published: (2022-08-01)
by: Feifei Nan, et al.
Published: (2022-08-01)
Chronic Lymphocytic Leukemia with Dermatomyositis: A Therapeutic Challenge
by: Sudhir Kumar, et al.
Published: (2020-11-01)
by: Sudhir Kumar, et al.
Published: (2020-11-01)
Similar Items
-
CAR T Cell Therapy for Chronic Lymphocytic Leukemia: Successes and Shortcomings
by: Zeljko Todorovic, et al.
Published: (2022-05-01) -
Preclinical evaluation of combination nemtabrutinib and venetoclax in chronic lymphocytic leukemia
by: Elizabeth M. Muhowski, et al.
Published: (2022-11-01) -
The regulation of tumor‐suppressive microRNA, miR‐126, in chronic lymphocytic leukemia
by: Daphne Guinn, et al.
Published: (2017-04-01) -
Pharmacists’ Role in Managing Patients with Chronic Lymphocytic Leukemia
by: Kevin Y. Chen, et al.
Published: (2020-03-01) -
Ibrutinib-Induced Cardiac Tamponade in Chronic Lymphocytic Leukemia
by: Keisuke Kidoguchi, et al.
Published: (2021-02-01)
