Cytology May not be Sufficient for Cervical Screening in Women with HPV Types Other than Type 16-type 18

Objective:The aim of this study was to examine the relationship between human papilloma virus (HPV) types 16-18 and other high risk HPV types and final pathology in HPV positive women who underwent colposcopy and loop electroincision procedure (LEEP).Method:The data of 528 HPV positive women hospita...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:Bagcilar Medical Bulletin
المؤلفون الرئيسيون: Erhan Okuyan, Özlem Karabay Akgül
التنسيق: مقال
اللغة:الإنجليزية
منشور في: Istanbul Bagcilar Training and Research Hospital 2023-03-01
الموضوعات:
الوصول للمادة أونلاين: http://behmedicalbulletin.org/archives/archive-detail/article-preview/cytology-may-not-be-sufficient-for-cervical-screen/58911
الوصف
الملخص:Objective:The aim of this study was to examine the relationship between human papilloma virus (HPV) types 16-18 and other high risk HPV types and final pathology in HPV positive women who underwent colposcopy and loop electroincision procedure (LEEP).Method:The data of 528 HPV positive women hospitalized at tertiary center between January 2017 and January 2019 were recorded retrospectively. The ages of the patients, smear results, HPV types, pathology results of colposcopic biopsies and pathology results of LEEP material in LEEP patients were evaluated. Women with HPV DNA type 16 and/or 18 named as high risk group (HRG) and women with high risk HPV DNA types other than type 16 and/or 18 (31, 33, 35, 39, 45, 51, 52, 56, 58, 59 and 68 types) named as other high risk group (OHRG). Pregnant women were not included in the study. Women with vaginal infections were included in the study after treatment. Both groups were statistically analyzed according their colposcopical and pathological findings.Results:There were 322 women (61%) in the OHRG. While there were benign findings in the colposcopy in approximately 75% of OHRG, cervical cancer was suspected in 3 (1%) of them. Benign colposcopic findings were the most common in the HRG, and CIN1 (30%) was the second most common. CIN3 and cancer were more common in the HRG (6.8% and 2.9%, respectively). 75% of the patients in the OHRG were followed up; 25% had LEEP. CIN1 was found in 18% of the women who underwent LEEP.Conclusion:In the OHRG, invasive cervical cancer was diagnosed in 2 patients, even if the smear was negative; for this reason, colposcopy may be required regardless of cytology, as in HPV 16 and 18 positivity in these patients.
تدمد:2547-9431