Pirfenidone slows the development of fibrosis and malignant neoplasms by modulating inflammation in an experimental model of hepatocarcinoma.

Introduction and objectives: Hepatocellular carcinoma (HCC) is the most common liver neoplasm in the world. Inflammatory, oxidative and fibrogenic processes are key in tumor development and propagation. Pirfenidone (PFD) has been shown to have hepatoprotective, anti-fibrogenic and immunomodulatory p...

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Bibliographic Details
Published in:Annals of Hepatology
Main Authors: Scarlet Arceo-Orozco, Fernado Caloca-Camarena, Marina Galicia-Moreno, Hugo C. Monroy-Ramírez, Juan Armendáriz-Borunda
Format: Article
Language:English
Published: Elsevier 2024-02-01
Online Access:http://www.sciencedirect.com/science/article/pii/S1665268124001947

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