Experimental Models of Cryptococcosis

Cryptococcosis is a life-threatening fungal disease that infects around one million people each year. Establishment and progression of disease involves a complex interplay between the fungus and a diverse range of host cell types. Over recent years, numerous cellular, tissue, and animal models have...

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Published in:International Journal of Microbiology
Main Authors: Wilber Sabiiti, Robin C. May, E. Rhiannon Pursall
Format: Article
Language:English
Published: Wiley 2012-01-01
Online Access:http://dx.doi.org/10.1155/2012/626745
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author Wilber Sabiiti
Robin C. May
E. Rhiannon Pursall
author_facet Wilber Sabiiti
Robin C. May
E. Rhiannon Pursall
author_sort Wilber Sabiiti
collection DOAJ
container_title International Journal of Microbiology
description Cryptococcosis is a life-threatening fungal disease that infects around one million people each year. Establishment and progression of disease involves a complex interplay between the fungus and a diverse range of host cell types. Over recent years, numerous cellular, tissue, and animal models have been exploited to probe this host-pathogen interaction. Here we review the range of experimental models that are available for cryptococcosis research and compare the relative advantages and limitations of the different systems.
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spelling doaj-art-7270fe702e0e4700a39bd026fe5277702025-08-20T03:33:45ZengWileyInternational Journal of Microbiology1687-918X1687-91982012-01-01201210.1155/2012/626745626745Experimental Models of CryptococcosisWilber Sabiiti0Robin C. May1E. Rhiannon Pursall2School of Biosciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UKSchool of Biosciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UKSchool of Biosciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UKCryptococcosis is a life-threatening fungal disease that infects around one million people each year. Establishment and progression of disease involves a complex interplay between the fungus and a diverse range of host cell types. Over recent years, numerous cellular, tissue, and animal models have been exploited to probe this host-pathogen interaction. Here we review the range of experimental models that are available for cryptococcosis research and compare the relative advantages and limitations of the different systems.http://dx.doi.org/10.1155/2012/626745
spellingShingle Wilber Sabiiti
Robin C. May
E. Rhiannon Pursall
Experimental Models of Cryptococcosis
title Experimental Models of Cryptococcosis
title_full Experimental Models of Cryptococcosis
title_fullStr Experimental Models of Cryptococcosis
title_full_unstemmed Experimental Models of Cryptococcosis
title_short Experimental Models of Cryptococcosis
title_sort experimental models of cryptococcosis
url http://dx.doi.org/10.1155/2012/626745
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