Antimicrobial resistance and stewardship: What do pharmacists know and practice in a major Nigerian tertiary health facility: A cross-sectional study

• 出版年: Journal of Clinical Sciences
• 主要な著者: Alero Ann Roberts, Indu Das, Babatunde A. Akodu, John Olatunde Aderemi, Sharon Chioma Ajudua, Chioma S. Osuagwu, Iretiolu B. Fajolu, Patricia Eyanya Akintan, Temilola Felicia Olufohunsi, Phillip Olayiwola Oshun, Olubusola Olugbake, Rebecca Oritsemaje Soremekun, Arinola Joda, Oyinlola O. Oduyebo
• フォーマット: 論文
• 言語: 英語
• 出版事項: Wolters Kluwer Medknow Publications 2024-05-01
• 主題: antimicrobial stewardship; knowledge and practices; lagos nigeria; pharmacists; tertiary health facility
• オンライン･アクセス: https://journals.lww.com/10.4103/jcls.jcls_88_23
• ISSN: 2468-6859; 2408-7408

Background: Multidrug-resistant bacterial infections are still a global challenge and successful antimicrobial stewardship (AMS) requires multidisciplinary collaborative partnership. Studies have highlighted the knowledge and perceptions of pharmacists, but there is a paucity of data about practices of pharmacists in teaching hospitals in Nigeria. We set out to determine the knowledge and practices of pharmacists in a major tertiary health facility (THF) in Lagos, Nigeria, before starting an AMS intervention program. Methods: This cross-sectional survey used electronic forms to find out the knowledge and practices of pharmacists employed in a large tertiary health facility. Data were collected during a Commonwealth Partnerships for AMS program to support low- and middle-income countries to produce antimicrobial consumption surveillance data, quality improvement initiatives, and infection prevention and control (IPC) processes. Results: Two-thirds of respondents knew that antibiotics were effective against bacteria, and 48.6% knew the causes of antimicrobial resistance. Almost all (97.1%) agreed that AMS must be done, IPC is important, and they were confident to point out inappropriate prescribing. Three-quarters had advised colleagues or been involved in AMS activities; however, 62.9% had fully or mostly changed their practices based on information received, and 26.5% had participated in World Antibiotic Awareness Week. Conclusion: There are still gaps in knowledge and practices, which underscore the need to entrench regular training on the job. However, there is overall awareness of AMS and a desire for it to be carried out at all levels. Pharmacists are useful for choosing appropriate antibiotics and can play a vital role in AMS.