The Association of SGLT-2 inhibitors (Empagliflozin) with the development of hypernatremic dehydration: a case report
Sodium-Glucose-Cotransporter -2 inhibitors (SGLT2 inhibitors) are a new class of drugs that reduce blood glucose levels by increasing glucose excretion and lowering blood pressure through natriuresis and plasma volumen contraction. Due to their beneficial effects, they are currently used in treatmen...
| Published in: | Iberoamerican Journal of Medicine |
|---|---|
| Main Authors: | , , , , , |
| Format: | Article |
| Language: | English |
| Published: |
Emergency Department of Hospital San Pedro (Logroño, Spain)
2025-10-01
|
| Subjects: | |
| Online Access: | https://doi.org/10.53986/ibjm.2025.0001 |
| _version_ | 1850004988568272896 |
|---|---|
| author | Diana Alegre-González Sandra García-Guerreros Sara Martínez-Hernández Ana Yasmina Brito-Díaz Marta Casañas-Martínez Ramón Baeza-Trinidad |
| author_facet | Diana Alegre-González Sandra García-Guerreros Sara Martínez-Hernández Ana Yasmina Brito-Díaz Marta Casañas-Martínez Ramón Baeza-Trinidad |
| author_sort | Diana Alegre-González |
| collection | DOAJ |
| container_title | Iberoamerican Journal of Medicine |
| description | Sodium-Glucose-Cotransporter -2 inhibitors (SGLT2 inhibitors) are a new class of drugs that reduce blood glucose levels by increasing glucose excretion and lowering blood pressure through natriuresis and plasma volumen contraction. Due to their beneficial effects, they are currently used in treatment of both diabetes mellitus and heart failure, leading to widespread use in recent years. Here, we present a case of a patient who experienced severe hypernatremic dehydration related to the initiation of treatment with iSGLT2 inhibitors. |
| format | Article |
| id | doaj-art-74ce7e88a44747bfa4e64bf1ddf0fc44 |
| institution | Directory of Open Access Journals |
| issn | 2695-5075 |
| language | English |
| publishDate | 2025-10-01 |
| publisher | Emergency Department of Hospital San Pedro (Logroño, Spain) |
| record_format | Article |
| spelling | doaj-art-74ce7e88a44747bfa4e64bf1ddf0fc442025-08-20T00:47:23ZengEmergency Department of Hospital San Pedro (Logroño, Spain)Iberoamerican Journal of Medicine2695-50752025-10-0171252810.53986/ibjm.2025.0001The Association of SGLT-2 inhibitors (Empagliflozin) with the development of hypernatremic dehydration: a case reportDiana Alegre-González0https://orcid.org/0000-0002-1677-3724Sandra García-Guerreros1Sara Martínez-Hernández2Ana Yasmina Brito-Díaz3Marta Casañas-Martínez4Ramón Baeza-Trinidad5https://orcid.org/0000-0002-7854-3115Department of Internal Medicine, Hospital San Pedro, Logroño, SpainDepartment of Internal Medicine, Hospital San Pedro, Logroño, SpainDepartment of Internal Medicine, Hospital San Pedro, Logroño, SpainDepartment of Internal Medicine, Hospital San Pedro, Logroño, SpainDepartment of Internal Medicine, Hospital San Pedro, Logroño, SpainDepartment of Internal Medicine, Hospital San Pedro, Logroño, SpainSodium-Glucose-Cotransporter -2 inhibitors (SGLT2 inhibitors) are a new class of drugs that reduce blood glucose levels by increasing glucose excretion and lowering blood pressure through natriuresis and plasma volumen contraction. Due to their beneficial effects, they are currently used in treatment of both diabetes mellitus and heart failure, leading to widespread use in recent years. Here, we present a case of a patient who experienced severe hypernatremic dehydration related to the initiation of treatment with iSGLT2 inhibitors.https://doi.org/10.53986/ibjm.2025.0001sglt-2 inhibitorsempagliflozinhypernatremiadehydration |
| spellingShingle | Diana Alegre-González Sandra García-Guerreros Sara Martínez-Hernández Ana Yasmina Brito-Díaz Marta Casañas-Martínez Ramón Baeza-Trinidad The Association of SGLT-2 inhibitors (Empagliflozin) with the development of hypernatremic dehydration: a case report sglt-2 inhibitors empagliflozin hypernatremia dehydration |
| title | The Association of SGLT-2 inhibitors (Empagliflozin) with the development of hypernatremic dehydration: a case report |
| title_full | The Association of SGLT-2 inhibitors (Empagliflozin) with the development of hypernatremic dehydration: a case report |
| title_fullStr | The Association of SGLT-2 inhibitors (Empagliflozin) with the development of hypernatremic dehydration: a case report |
| title_full_unstemmed | The Association of SGLT-2 inhibitors (Empagliflozin) with the development of hypernatremic dehydration: a case report |
| title_short | The Association of SGLT-2 inhibitors (Empagliflozin) with the development of hypernatremic dehydration: a case report |
| title_sort | association of sglt 2 inhibitors empagliflozin with the development of hypernatremic dehydration a case report |
| topic | sglt-2 inhibitors empagliflozin hypernatremia dehydration |
| url | https://doi.org/10.53986/ibjm.2025.0001 |
| work_keys_str_mv | AT dianaalegregonzalez theassociationofsglt2inhibitorsempagliflozinwiththedevelopmentofhypernatremicdehydrationacasereport AT sandragarciaguerreros theassociationofsglt2inhibitorsempagliflozinwiththedevelopmentofhypernatremicdehydrationacasereport AT saramartinezhernandez theassociationofsglt2inhibitorsempagliflozinwiththedevelopmentofhypernatremicdehydrationacasereport AT anayasminabritodiaz theassociationofsglt2inhibitorsempagliflozinwiththedevelopmentofhypernatremicdehydrationacasereport AT martacasanasmartinez theassociationofsglt2inhibitorsempagliflozinwiththedevelopmentofhypernatremicdehydrationacasereport AT ramonbaezatrinidad theassociationofsglt2inhibitorsempagliflozinwiththedevelopmentofhypernatremicdehydrationacasereport AT dianaalegregonzalez associationofsglt2inhibitorsempagliflozinwiththedevelopmentofhypernatremicdehydrationacasereport AT sandragarciaguerreros associationofsglt2inhibitorsempagliflozinwiththedevelopmentofhypernatremicdehydrationacasereport AT saramartinezhernandez associationofsglt2inhibitorsempagliflozinwiththedevelopmentofhypernatremicdehydrationacasereport AT anayasminabritodiaz associationofsglt2inhibitorsempagliflozinwiththedevelopmentofhypernatremicdehydrationacasereport AT martacasanasmartinez associationofsglt2inhibitorsempagliflozinwiththedevelopmentofhypernatremicdehydrationacasereport AT ramonbaezatrinidad associationofsglt2inhibitorsempagliflozinwiththedevelopmentofhypernatremicdehydrationacasereport |