IGF-I, IGF-II and insulin stimulate different gene expression responses through binding to the IGF-I receptor.

Insulin and the insulin-like growth factors (IGF)-I and –II are closely related peptides important for regulation of metabolism, growth, differentiation and development. The IGFs exert their main effects through the IGF-I receptor. Although the insulin receptor is the main physiological receptor for...

وصف كامل

التفاصيل البيبلوغرافية

الحاوية / القاعدة:	Frontiers in Endocrinology
المؤلفون الرئيسيون:	Soetkin eVersteyhe, Birgit eKlaproth, Rehannah eBorup, Jane ePalsgaard, Maja eJensen, Steven G. Gray, Pierre eDe Meyts
التنسيق:	مقال
اللغة:	الإنجليزية
منشور في:	Frontiers Media S.A. 2013-08-01
الموضوعات:	Insulin Differential signaling IGF IGF-I receptor microarray gene expression
الوصول للمادة أونلاين:	http://journal.frontiersin.org/Journal/10.3389/fendo.2013.00098/full