(<i>E</i>)-2-(2-Oxo-4-phenylbut-3-en-1-yl)benzo[<i>d</i>]thiazole-3(2<i>H</i>)-carboxylates
An convenient one-pot approach for the synthesis of new (<i>E</i>)-2-(2-oxo-4-phenylbut-3-en-1-yl)benzo[<i>d</i>]thiazole-3(2<i>H</i>)-carboxylates is demonstrated. The method is based on a three-component reaction of benzylideneacetone with electrophilic <i>...
| Published in: | Molbank |
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| Main Authors: | , |
| Format: | Article |
| Language: | English |
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MDPI AG
2021-06-01
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| Online Access: | https://www.mdpi.com/1422-8599/2021/2/M1236 |
| _version_ | 1851841742211383296 |
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| author | Yordan Stremski Stela Statkova-Abeghe |
| author_facet | Yordan Stremski Stela Statkova-Abeghe |
| author_sort | Yordan Stremski |
| collection | DOAJ |
| container_title | Molbank |
| description | An convenient one-pot approach for the synthesis of new (<i>E</i>)-2-(2-oxo-4-phenylbut-3-en-1-yl)benzo[<i>d</i>]thiazole-3(2<i>H</i>)-carboxylates is demonstrated. The method is based on a three-component reaction of benzylideneacetone with electrophilic <i>N</i>-alkoxycarbonylbenzothiazolium species formed <i>in situ</i>. The newly synthesized compounds were fully characterized by 1D <sup>1</sup>H, <sup>13</sup>C- NMR, IR and MS. |
| format | Article |
| id | doaj-art-7828cbc1882f45e6b0d2d22f2acace44 |
| institution | Directory of Open Access Journals |
| issn | 1422-8599 |
| language | English |
| publishDate | 2021-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| spelling | doaj-art-7828cbc1882f45e6b0d2d22f2acace442025-08-19T22:28:09ZengMDPI AGMolbank1422-85992021-06-0120212M123610.3390/M1236(<i>E</i>)-2-(2-Oxo-4-phenylbut-3-en-1-yl)benzo[<i>d</i>]thiazole-3(2<i>H</i>)-carboxylatesYordan Stremski0Stela Statkova-Abeghe1Department of Organic Chemistry, University of Plovdiv Paisii Hilendarski, 24 Tsar Asen Str., 4000 Plovdiv, BulgariaDepartment of Organic Chemistry, University of Plovdiv Paisii Hilendarski, 24 Tsar Asen Str., 4000 Plovdiv, BulgariaAn convenient one-pot approach for the synthesis of new (<i>E</i>)-2-(2-oxo-4-phenylbut-3-en-1-yl)benzo[<i>d</i>]thiazole-3(2<i>H</i>)-carboxylates is demonstrated. The method is based on a three-component reaction of benzylideneacetone with electrophilic <i>N</i>-alkoxycarbonylbenzothiazolium species formed <i>in situ</i>. The newly synthesized compounds were fully characterized by 1D <sup>1</sup>H, <sup>13</sup>C- NMR, IR and MS.https://www.mdpi.com/1422-8599/2021/2/M1236benzothiazolebenzylideneacetoneα-amidoalkylationmulticomponent reaction |
| spellingShingle | Yordan Stremski Stela Statkova-Abeghe (<i>E</i>)-2-(2-Oxo-4-phenylbut-3-en-1-yl)benzo[<i>d</i>]thiazole-3(2<i>H</i>)-carboxylates benzothiazole benzylideneacetone α-amidoalkylation multicomponent reaction |
| title | (<i>E</i>)-2-(2-Oxo-4-phenylbut-3-en-1-yl)benzo[<i>d</i>]thiazole-3(2<i>H</i>)-carboxylates |
| title_full | (<i>E</i>)-2-(2-Oxo-4-phenylbut-3-en-1-yl)benzo[<i>d</i>]thiazole-3(2<i>H</i>)-carboxylates |
| title_fullStr | (<i>E</i>)-2-(2-Oxo-4-phenylbut-3-en-1-yl)benzo[<i>d</i>]thiazole-3(2<i>H</i>)-carboxylates |
| title_full_unstemmed | (<i>E</i>)-2-(2-Oxo-4-phenylbut-3-en-1-yl)benzo[<i>d</i>]thiazole-3(2<i>H</i>)-carboxylates |
| title_short | (<i>E</i>)-2-(2-Oxo-4-phenylbut-3-en-1-yl)benzo[<i>d</i>]thiazole-3(2<i>H</i>)-carboxylates |
| title_sort | i e i 2 2 oxo 4 phenylbut 3 en 1 yl benzo i d i thiazole 3 2 i h i carboxylates |
| topic | benzothiazole benzylideneacetone α-amidoalkylation multicomponent reaction |
| url | https://www.mdpi.com/1422-8599/2021/2/M1236 |
| work_keys_str_mv | AT yordanstremski iei22oxo4phenylbut3en1ylbenzoidithiazole32ihicarboxylates AT stelastatkovaabeghe iei22oxo4phenylbut3en1ylbenzoidithiazole32ihicarboxylates |