Protector effect of Helianthus annuus (Sunflower) on myocardial infarction in New Zealand rabbit

• Published in: Revista Peruana de Medicina Experimental y Salud Pública
• Main Authors: Edith Guardia-Espinoza, Gianina Liseth del Carmen Herrera-Hurtado, Saúl Garrido-Jacobi, Danitza Cárdenas-Peralta, Christian Martínez-Romero, Pedro Hernández-Figueroa, Mary Condori-Calizaya, Juan La Barrera-Llacchua, Miguel Flores-Ángeles
• Format: Article
• Language: Spanish
• Published: Instituto Nacional de Salud 2015-04-01
• Subjects: infarto del miocardio; helianthus annuus; epinefrina
• Online Access: https://rpmesp.ins.gob.pe/index.php/rpmesp/article/view/1578
• ISSN: 1726-4634; 1726-4642

Objectives. Determine the protective effect of oil Helianthus annuus (Sunflower) on myocardial infarction induced by epinephrine in New Zealand rabbits. Materials and methods. The rabbits were randomized into five groups (8 per group): blank, negative control, experimental 1 (10 mg / kg), experimental 2 (20 mg / kg) and three experimental (40 mg/ kg). Experimental groups 1, 2 and 3 received Helianthus annuus oil for two weeks. Epinephrine (2 mg/Kg) to the negative, Experimental Control 1, 2 and 3 groups was given over two consecutive days with an interval of 24 h after pretreatment with oil. Twenty four hours after the last administration, the rabbits were anesthetized and sacrificed. Serum troponin I and polymorphonuclear evaluated by .mu.m.sup.2. Results. Significant difference between the negative control group and the experimental groups 1, 2 and 3 was found in the serum variables troponin I and polymorphonuclear by .mu.m.sup.2. Conclusions. Helianthus annuus oil at doses of 20 mg/kg has protective effect on myocardial infarction induced by epinephrine in New Zealand rabbits.