Hot Melt Coating of Amorphous Carvedilol

The use of amorphous drug delivery systems is an attractive approach to improve the bioavailability of low molecular weight drug candidates that suffer from poor aqueous solubility. However, the pharmaceutical performance of many neat amorphous drugs is compromised by their tendency for recrystalliz...

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Bibliographic Details
Published in:	Pharmaceutics
Main Authors:	Jacob Bannow, Lina Koren, Sharareh Salar-Behzadi, Korbinian Löbmann, Andreas Zimmer, Thomas Rades
Format:	Article
Language:	English
Published:	MDPI AG 2020-06-01
Subjects:	hot melt coating (HMC) amorphous solids solid-state amorphous stability amorphous drug delivery dynamic in vitro lipolysis
Online Access:	https://www.mdpi.com/1999-4923/12/6/519

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