A primary neural cell culture model to study neuron, astrocyte, and microglia interactions in neuroinflammation
Abstract Background Interactions between neurons, astrocytes, and microglia critically influence neuroinflammatory responses to insult in the central nervous system. In vitro astrocyte and microglia cultures are powerful tools to study specific molecular pathways involved in neuroinflammation; howev...
| Published in: | Journal of Neuroinflammation |
|---|---|
| Main Authors: | Noah Goshi, Rhianna K. Morgan, Pamela J. Lein, Erkin Seker |
| Format: | Article |
| Language: | English |
| Published: |
BMC
2020-05-01
|
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s12974-020-01819-z |
Similar Items
Electrophysiological Activity of Primary Cortical Neuron-Glia Mixed Cultures
by: Noah Goshi, et al.
Published: (2023-03-01)
by: Noah Goshi, et al.
Published: (2023-03-01)
The roles of microglia and astrocytes in neuroinflammation of Alzheimer’s disease
by: Jialin Han, et al.
Published: (2025-05-01)
by: Jialin Han, et al.
Published: (2025-05-01)
Peptide discovery across the spectrum of neuroinflammation; microglia and astrocyte phenotypical targeting, mediation, and mechanistic understanding
by: Benjamin A. Benita, et al.
Published: (2024-11-01)
by: Benjamin A. Benita, et al.
Published: (2024-11-01)
Prevention and Treatment Strategies for Alzheimer’s Disease: Focusing on Microglia and Astrocytes in Neuroinflammation
by: Zhang S, et al.
Published: (2024-10-01)
by: Zhang S, et al.
Published: (2024-10-01)
DICAM in the Extracellular Vesicles from Astrocytes Attenuates Microglia Activation and Neuroinflammation
by: Jin Han, et al.
Published: (2022-09-01)
by: Jin Han, et al.
Published: (2022-09-01)
Role of Microglia and Astrocytes in Alzheimer’s Disease: From Neuroinflammation to Ca<sup>2+</sup> Homeostasis Dysregulation
by: Giulia Di Benedetto, et al.
Published: (2022-09-01)
by: Giulia Di Benedetto, et al.
Published: (2022-09-01)
A primary rat neuron-astrocyte-microglia tri-culture model for studying mechanisms of neurotoxicity
by: Jessie R. Badley, et al.
Published: (2025-01-01)
by: Jessie R. Badley, et al.
Published: (2025-01-01)
Microglia and astrocytes underlie neuroinflammation and synaptic susceptibility in autism spectrum disorder
by: Yue Xiong, et al.
Published: (2023-03-01)
by: Yue Xiong, et al.
Published: (2023-03-01)
Emerging role of non-coding RNAs in neuroinflammation mediated by microglia and astrocytes
by: Ruicheng Yang, et al.
Published: (2023-07-01)
by: Ruicheng Yang, et al.
Published: (2023-07-01)
The Role of Microglia and Astrocytes in Huntington’s Disease
by: Thulani H. Palpagama, et al.
Published: (2019-10-01)
by: Thulani H. Palpagama, et al.
Published: (2019-10-01)
Editorial: Neuroinflammation and cognitive impairment
by: Juan Li, et al.
Published: (2024-07-01)
by: Juan Li, et al.
Published: (2024-07-01)
Microglia–Astrocyte Interaction in Neural Development and Neural Pathogenesis
by: Meiqi Sun, et al.
Published: (2023-07-01)
by: Meiqi Sun, et al.
Published: (2023-07-01)
Astrocyte–microglia crosstalk in subarachnoid hemorrhage: mechanisms and treatments
by: Kaibo Yu, et al.
Published: (2025-06-01)
by: Kaibo Yu, et al.
Published: (2025-06-01)
The dual nature of neuroinflammation in networked brain
by: Ludmila Müller, et al.
Published: (2025-08-01)
by: Ludmila Müller, et al.
Published: (2025-08-01)
METABOLIC REPROGRAMMING OF MICROGLIA AND ASTROCYTES AS A FACTOR IN THE REGULATION OF NEUROINFLAMMATION IN ISCHEMIC STROKE
by: Mikhail Bobrov, et al.
Published: (2019-08-01)
by: Mikhail Bobrov, et al.
Published: (2019-08-01)
Microglia and astrocyte involvement in neurodegeneration and brain cancer
by: Arthur A. Vandenbark, et al.
Published: (2021-12-01)
by: Arthur A. Vandenbark, et al.
Published: (2021-12-01)
The angiotensin II receptors type 1 and 2 modulate astrocytes and their crosstalk with microglia and neurons in an in vitro model of ischemic stroke
by: Daniel Navin Olschewski, et al.
Published: (2024-06-01)
by: Daniel Navin Olschewski, et al.
Published: (2024-06-01)
Pharmacological modulation of TSPO in microglia/macrophages and neurons in a chronic neurodegenerative model of prion disease
by: Marta Vicente-Rodríguez, et al.
Published: (2023-04-01)
by: Marta Vicente-Rodríguez, et al.
Published: (2023-04-01)
Crosstalk Between Astrocytes and Microglia: An Overview
by: Agata Matejuk, et al.
Published: (2020-07-01)
by: Agata Matejuk, et al.
Published: (2020-07-01)
Astrocytic and microglial cells as the modulators of neuroinflammation in Alzheimer’s disease
by: Deepali Singh
Published: (2022-08-01)
by: Deepali Singh
Published: (2022-08-01)
Influence of antipsychotic drugs on microglia-mediated neuroinflammation in schizophrenia: perspectives in an astrocyte–microglia co-culture model
by: Timo Jendrik Faustmann, et al.
Published: (2025-03-01)
by: Timo Jendrik Faustmann, et al.
Published: (2025-03-01)
Paroxetine suppresses reactive microglia-mediated but not lipopolysaccharide-induced inflammatory responses in primary astrocytes
by: Xiong Zhang, et al.
Published: (2020-02-01)
by: Xiong Zhang, et al.
Published: (2020-02-01)
Primary Cortical Cell Tri-Culture-Based Screening of Neuroinflammatory Response in Toll-like Receptor Activation
by: Noah Goshi, et al.
Published: (2022-08-01)
by: Noah Goshi, et al.
Published: (2022-08-01)
The Role of Microglia and Astrocytes in the Pathomechanism of Neuroinflammation in Parkinson’s Disease—Focus on Alpha-Synuclein
by: Oliwia Harackiewicz, et al.
Published: (2024-11-01)
by: Oliwia Harackiewicz, et al.
Published: (2024-11-01)
Neuroimmune crosstalk in chronic neuroinflammation: microglial interactions and immune modulation
by: Ludmila Müller, et al.
Published: (2025-04-01)
by: Ludmila Müller, et al.
Published: (2025-04-01)
From Homeostasis to Neuroinflammation: Insights into Cellular and Molecular Interactions and Network Dynamics
by: Ludmila Müller, et al.
Published: (2025-01-01)
by: Ludmila Müller, et al.
Published: (2025-01-01)
Stress-Induced Sleep Dysregulation: The Roles of Astrocytes and Microglia in Neurodegenerative and Psychiatric Disorders
by: Ángel R. Rábago-Monzón, et al.
Published: (2025-05-01)
by: Ángel R. Rábago-Monzón, et al.
Published: (2025-05-01)
Hyperglycemia enhances brain susceptibility to lipopolysaccharide-induced neuroinflammation via astrocyte reprogramming
by: Kyung-Seo Lee, et al.
Published: (2024-05-01)
by: Kyung-Seo Lee, et al.
Published: (2024-05-01)
Circadian cycle and neuroinflammation
by: Xu Xinzi, et al.
Published: (2023-10-01)
by: Xu Xinzi, et al.
Published: (2023-10-01)
Inhibition of astrocyte signaling leads to sex-specific changes in microglia phenotypes in a diet-based model of cerebral small vessel disease
by: Jenna L. Gollihue, et al.
Published: (2025-08-01)
by: Jenna L. Gollihue, et al.
Published: (2025-08-01)
Neuroinflammation in epileptogenesis: from pathophysiology to therapeutic strategies
by: Wenjun Li, et al.
Published: (2023-12-01)
by: Wenjun Li, et al.
Published: (2023-12-01)
Lactic acid regulates lipid droplet aggregation through a microglia-neuron axis in neuroinflammation
by: Zhuoqing Lan, et al.
Published: (2024-10-01)
by: Zhuoqing Lan, et al.
Published: (2024-10-01)
The Role of Microglia in Neuroinflammation of the Spinal Cord after Peripheral Nerve Injury
by: Tana S. Pottorf, et al.
Published: (2022-06-01)
by: Tana S. Pottorf, et al.
Published: (2022-06-01)
Sequential Isolation of Microglia and Astrocytes from Young and Aged Adult Mouse Brains for Downstream Transcriptomic Analysis
by: Ruchelle G. Buenaventura, et al.
Published: (2022-09-01)
by: Ruchelle G. Buenaventura, et al.
Published: (2022-09-01)
Absence of BBSome function leads to astrocyte reactivity in the brain
by: Minati Singh, et al.
Published: (2019-05-01)
by: Minati Singh, et al.
Published: (2019-05-01)
Microglia-Astroglia-Neuron network following stroke: Novel insight into extracellular vesicles communication
by: Hao Wan, et al.
Published: (2025-10-01)
by: Hao Wan, et al.
Published: (2025-10-01)
Hippocampal neuroinflammation and neuronal injury in the acute phase of pentylenetetrazol induced epilepsy mouse model
by: Linyu ZHI, et al.
Published: (2025-04-01)
by: Linyu ZHI, et al.
Published: (2025-04-01)
Senescent Phenotype of Astrocytes Leads to Activation of BV2 Microglia and N2a Neuronal Cells Death
by: Wenyou Zhang, et al.
Published: (2022-09-01)
by: Wenyou Zhang, et al.
Published: (2022-09-01)
Phagocytic Activities of Reactive Microglia and Astrocytes Associated with Prion Diseases Are Dysregulated in Opposite Directions
by: Anshuman Sinha, et al.
Published: (2021-07-01)
by: Anshuman Sinha, et al.
Published: (2021-07-01)
Cottonseed oil alleviates ischemic stroke injury by inhibiting the inflammatory activation of microglia and astrocyte
by: Min Liu, et al.
Published: (2020-09-01)
by: Min Liu, et al.
Published: (2020-09-01)
Similar Items
-
Electrophysiological Activity of Primary Cortical Neuron-Glia Mixed Cultures
by: Noah Goshi, et al.
Published: (2023-03-01) -
The roles of microglia and astrocytes in neuroinflammation of Alzheimer’s disease
by: Jialin Han, et al.
Published: (2025-05-01) -
Peptide discovery across the spectrum of neuroinflammation; microglia and astrocyte phenotypical targeting, mediation, and mechanistic understanding
by: Benjamin A. Benita, et al.
Published: (2024-11-01) -
Prevention and Treatment Strategies for Alzheimer’s Disease: Focusing on Microglia and Astrocytes in Neuroinflammation
by: Zhang S, et al.
Published: (2024-10-01) -
DICAM in the Extracellular Vesicles from Astrocytes Attenuates Microglia Activation and Neuroinflammation
by: Jin Han, et al.
Published: (2022-09-01)
