Mutation of Mycobacterium tuberculosis and Implications for Using Whole-Genome Sequencing for Investigating Recent Tuberculosis Transmission

Tuberculosis (TB) control programs use whole-genome sequencing (WGS) of Mycobacterium tuberculosis (Mtb) for detecting and investigating TB case clusters. Existence of few genomic differences between Mtb isolates might indicate TB cases are the result of recent transmission. However, the variable an...

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Bibliographic Details
Published in:	Frontiers in Public Health
Main Authors:	Kristin N. Nelson, Sarah Talarico, Shameer Poonja, Clinton J. McDaniel, Martin Cilnis, Alicia H. Chang, Kala Raz, Wendy S. Noboa, Lauren Cowan, Tambi Shaw, James Posey, Benjamin J. Silk
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-01-01
Subjects:	tuberculosis—epidemiology prevention and control genomic sequencing tuberculosis transmission public health practice
Online Access:	https://www.frontiersin.org/articles/10.3389/fpubh.2021.790544/full

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