The effect of preemptive gabapentin and pregabalin on postoperative pain of septoplasty with and without turbinoplasty: a randomized triple-blind controlled clinical trial

Abstract Background Septoplasty is a painful process. Nowadays, opioids and non-opioids are used to control patients’ pain, which has different efficacy and consequences. We aimed to assess the effect of preemptive gabapentin and pregabalin on postoperative pain of septoplasty with and without turbi...

Full description

Bibliographic Details
Published in:	The Egyptian Journal of Otolaryngology
Main Authors:	Rohollah Abbasi, Farnaz Hashemian, Mohammad Saeed Ahmadi, Javaneh Jahanshahi, Ebrahim Khoshraftar, Amin Karimian, Abbas Moradi
Format:	Article
Language:	English
Published:	SpringerOpen 2023-09-01
Subjects:	Gabapentin Pregabalin Postoperative pain Septoplasty Turbinoplasty
Online Access:	https://doi.org/10.1186/s43163-023-00502-3

Similar Items

Improvement of Nasal Obstruction Symptoms after Septoplasty with or without Turbinoplasty
by: Shafaq Zaman, et al.
Published: (2023-12-01)

ASSESSMENT OF PATIENT BENEFIT FROM SEPTOPLASTY WITH TURBINOPLASTY
by: Ahmad Jawad Samadi
Published: (2021-06-01)

A randomized trial comparing the efficacy of oral preemptive pregabalin and gabapentin for postoperative analgesia
by: T Krishna Prasad, et al.
Published: (2023-01-01)

A Comparison of Oral Gabapentin and Oral Pregabalin as Preemptive Analgesia for Orthopedic Surgery Under Spinal Anaesthesia
by: Jain Neena1 , Bankapur Rahul2 , Lamba Preeti3 , Saurav Singh4
Published: (2021-08-01)

Gabapentin and pregabalin exposures reported to United States poison centers, 2012–2022
by: Emily J.R. Carter, et al.
Published: (2024-11-01)

Comparison of Pregabalin and Gabapentin as Pre-emptive Analgesics in Patients Undergoing Abdominal Surgeries
by: Hafiz Ahmed Hassam Bhalli, et al.
Published: (2023-04-01)

The effect of gabapentin and pregabalin on intestinal incision wound healing in rabbits
by: M. Korkmaz, et al.
Published: (2015-03-01)

A Systematic Review of the Clinical Use of Gabapentin and Pregabalin in Bipolar Disorder
by: Qin Xiang Ng, et al.
Published: (2021-08-01)

Do gabapentin or pregabalin directly modulate the µ receptor?
by: Preeti Manandhar, et al.
Published: (2021-04-01)

Abuse liability of gabapentin in the Saudi population after the pregabalin restriction: A cross-sectional study
by: Amina A. Alkhalaf, PharmD, et al.
Published: (2021-10-01)

Trends in Nasal Septal and Inferior Turbinate Surgery in Korea From 2010 to 2022
by: Taehee Kim, et al.
Published: (2023-11-01)

Septoplasty‐mediated improvements in nasal patency and pulmonary function: A prospective study
by: Francisco Alves deSousa, et al.
Published: (2025-02-01)

Comparison of the Anxiolytic and Analgesic Effects of Gabapentin and Pregabalin in Cats: A Systematic Review
by: Agatha Elisa Miranda-Cortés, et al.
Published: (2025-08-01)

A Dyskinesia Case Induced by Pramipexole, Pregabalin and Gabapentin After Cardiopulmonary Resuscitation
by: Dürdane Aksoy, et al.
Published: (2013-12-01)

Efficacy and safety of pregabalin and gabapentin in spinal stenosis: a systematic review and meta-analysis
by: Telmo Martínez, et al.
Published: (2023-11-01)

Endoscopic Septoturbinoplasty among Patients Undergoing Surgery in the Department of Otolaryngology-Head and Neck of a Tertiary Care Hospital: A Descriptive Cross-sectional Study
by: Nain Bahadur Mahato, et al.
Published: (2021-12-01)

Pregabalin versus gabapentin in the treatment of sciatica: study protocol for a randomised, double-blind, cross-over trial (PAGPROS)
by: Kelvin Robertson, et al.
Published: (2018-01-01)

Microdebrider-Assisted Turbinoplasty in Children with Hypertrophic Inferior Turbinate
by: Ashraf Khalid, et al.
Published: (2022-04-01)

The impact of pregabalin and gabapentin on essential tremor: a systematic review and meta-analysis
by: Hooman Pourbala, et al.
Published: (2025-01-01)

Association of perioperative initiation of gabapentin versus pregabalin with kidney function: a target trial emulation study
by: Yanfang He, et al.
Published: (2024-12-01)

Pregabalin vs. gabapentin in the treatment of neuropathic pain: a comprehensive systematic review and meta-analysis of effectiveness and safety
by: Víctor Mayoral, et al.
Published: (2025-01-01)

The association between Gabapentin or Pregabalin use and the risk of dementia: an analysis of the National Health Insurance Research Database in Taiwan
by: Yu-Hua Huang, et al.
Published: (2023-05-01)

Pregabalin and gabapentin for chronic low back pain without radiculopathy: a systematic review
by: Rafael Trindade Tatit, et al.
Published: (2023-06-01)

Comparative evaluation between oral gabapentin and oral pregabalin premedication for attenuation of hemodynamic surge to laryngoscopy and endotracheal intubation in elective procedures under general anesthesia
by: Kunal Chandra Dubey, et al.
Published: (2024-03-01)

Comparison of the effects of preoperative gabapentin and pregabalin on postoperative analgesic consumption, urinary retention and nausea-vomiting in patients undergoing anorectal surgery under spinal anesthesia
by: Tülin Arıcı, et al.
Published: (2020-09-01)

High-dose use of pregabalin and gabapentin in France: a retrospective, population-based cohort studyResearch in context
by: Thomas Soeiro, et al.
Published: (2025-10-01)

Comparative efficacy and safety of gabapentin, pregabalin, oxcarbazepine, and duloxetine in diabetic peripheral neuropathy: A network meta-analysis
by: Karan Bhavesh Shah, et al.
Published: (2024-10-01)

Effect of the frequently used antiepileptic drugs carbamazepine, gabapentin, and pregabalin on the pharmacokinetics of edoxaban and other oral factor xa inhibitors in healthy volunteers
by: Alexander Lenard, et al.
Published: (2025-04-01)

Benefits of Turbinectomy vs Turbinoplasty – A Prospective Study
by: Revathi Thirugnanamani, et al.
Published: (2021-09-01)

Benefits of Turbinectomy vs Turbinoplasty – A Prospective Study
by: Revathi Thirugnanamani, et al.
Published: (2021-09-01)

Powered turbinoplasty versus powered turbinectomy: a comparative study
by: Sherif Gabr Ibrahim, et al.
Published: (2017-02-01)

Endoscopic Assisted Septoplasty Versus Conventional Septoplasty;a Prospective Study
by: Hardy Sirwan Muhammed, et al.
Published: (2023-05-01)

A Comparative Study of Conventional vs. Endoscopic Septoplasty
by: Bhagyesh Lalitchandra Darji
Published: (2024-12-01)

Endoscopic-assisted septoplasty versus traditional septoplasty: assessment by the NOSE scale
by: Sherif S. Guindi, et al.
Published: (2016-02-01)

Considerations When Using Gabapentinoids to Treat Trigeminal Neuralgia: A Review
by: De Stefano G, et al.
Published: (2023-09-01)

Gabapentinoid prescription in Oral Medicine and Oral Surgery practice. Part II − a systematic scoping review of the literature
by: Sulukdjian Arek, et al.
Published: (2020-01-01)

Postoperative Subjective and Objective Evaluation of Septoturbinoplasy Surgery in Mongolian Patients with Nasal Obstruction Symptom
by: Munkhbaatar Purev, et al.
Published: (2021-12-01)

Efficiency of modified Goldman’s technique in open pediatric septoplasty
by: Omar Sabry, et al.
Published: (2021-02-01)

Green Bio-Analytical Study of Gabapentin in Human Plasma Coupled with Pharmacokinetic and Bioequivalence Assessment Using UPLC-MS/MS
by: Rehab Moussa Tony, et al.
Published: (2023-04-01)

Chemical septoplasty using papain enzyme—a feasibility study
by: Arun Angelo Patil, et al.
Published: (2021-10-01)