GLOBAL COMPARATIVE ANTITHROMBIN-FIELD STUDY: IMPACT OF LABORATORY ASSAY VARIABILITY ON THE ASSESSMENT OF ANTITHROMBIN ACTIVITY MEASUREMENT
Objectives: Fitusiran is an investigational, subcutaneous small interfering RNA therapeutic in development for hemophilia A and B, with and without inhibitors that aims to rebalance hemostasis by targeting antithrombin (AT) mRNA to lower AT levels and restore sufficient thrombin generation. To furth...
| Published in: | Hematology, Transfusion and Cell Therapy |
|---|---|
| Main Authors: | E Seth-Chhabra, A Sadeghi-Khomami, Mingjie-Liu, Guy-Young, S W-Pipe, MC Ozelo, C Le-Camus, M Toh, SA Lima-Montalvao, Marek-Demissie |
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2024-10-01
|
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2531137924005923 |
Similar Items
Evaluation of the interference of fitusiran and antithrombin lowering in plasma on routine coagulation assays
by: Ekta Seth Chhabra, et al.
Published: (2025-08-01)
by: Ekta Seth Chhabra, et al.
Published: (2025-08-01)
Antithrombin supplementation to prevent venous thromboembolism: A case of hereditary antithrombin deficiency with increased antithrombin clearance during pregnancy and peripartum
by: Ayako Kaneda-Takeuchi, et al.
Published: (2025-06-01)
by: Ayako Kaneda-Takeuchi, et al.
Published: (2025-06-01)
Comparison of antithrombin activity assays in detection of patients with heparin binding site antithrombin deficiency: systematic review and meta-analysis
by: Tamara Rojnik, et al.
Published: (2023-10-01)
by: Tamara Rojnik, et al.
Published: (2023-10-01)
SAFETY AND EFFICACY OF THE FITUSIRAN REVISED ANTITHROMBIN-BASED DOSE REGIMEN IN PEOPLE WITH HAEMOPHILIA A OR B, WITH OR WITHOUT INHIBITORS (ATLAS-OLE)
by: Guy-Young, et al.
Published: (2024-10-01)
by: Guy-Young, et al.
Published: (2024-10-01)
Successful administration of recombinant human antithrombin in a pregnant Japanese woman with hereditary antithrombin deficiency
by: Yuya Fujibe, et al.
Published: (2019-11-01)
by: Yuya Fujibe, et al.
Published: (2019-11-01)
Plasmapheresis for the Treatment of Iatrogenic Antithrombin Excess as a Result of Spuriously Low Antithrombin Activity Measurements
by: Reza Zarinshenas, et al.
Published: (2020-01-01)
by: Reza Zarinshenas, et al.
Published: (2020-01-01)
Antithrombin Murcia (K241E) causing antithrombin deficiency: a possible role for altered glycosylation
by: Irene Martínez-Martínez, et al.
Published: (2010-08-01)
by: Irene Martínez-Martínez, et al.
Published: (2010-08-01)
Insight into Residues Critical for Antithrombin Function from an Expanded Database of Sequences That Includes Frog, Turtle and Ostrich Antithrombins
by: Marija Backovic, et al.
Published: (2002-01-01)
by: Marija Backovic, et al.
Published: (2002-01-01)
Investigation of the Differences in Antithrombin to Heparin Binding among Antithrombin Budapest 3, Basel, and Padua Mutations by Biochemical and In Silico Methods
by: Réka Gindele, et al.
Published: (2021-04-01)
by: Réka Gindele, et al.
Published: (2021-04-01)
Sulfated cellulose thin films with antithrombin affinity
Published: (2009-11-01)
Published: (2009-11-01)
MPI-CDG with transient hypoglycosylation and antithrombin deficiency
by: María Eugenia de la Morena-Barrio, et al.
Published: (2019-02-01)
by: María Eugenia de la Morena-Barrio, et al.
Published: (2019-02-01)
Antithrombin Therapy: Current State and Future Outlook
by: George M. Rodgers MD, PhD, et al.
Published: (2023-10-01)
by: George M. Rodgers MD, PhD, et al.
Published: (2023-10-01)
Decreased antithrombin activity in the early phase of trauma is strongly associated with extravascular leakage, but not with antithrombin consumption: a prospective observational study
by: Hironori Matsumoto, et al.
Published: (2018-08-01)
by: Hironori Matsumoto, et al.
Published: (2018-08-01)
Effect of frozen storage conditions on antithrombin protein C and protein S activity assay stability
by: Houmei Feng, et al.
Published: (2024-07-01)
by: Houmei Feng, et al.
Published: (2024-07-01)
Antithrombin, COVID-19, and Fresh Frozen Plasma Treatment
by: Rujittika Mungmunpuntipantip, et al.
Published: (2021-06-01)
by: Rujittika Mungmunpuntipantip, et al.
Published: (2021-06-01)
Supplementation therapy with Antithrombin Drugs in the Combined Treatment of Sepsis
by: I. V. Redkin, et al.
Published: (2019-11-01)
by: I. V. Redkin, et al.
Published: (2019-11-01)
Correction of Antithrombin III Deficiency in Disseminated Intravascular Coagulation
by: Ye. L. Neporada, et al.
Published: (2008-10-01)
by: Ye. L. Neporada, et al.
Published: (2008-10-01)
Protein C and antithrombin III in children with acute leukemia
by: F Atlihan, et al.
Published: (1993-01-01)
by: F Atlihan, et al.
Published: (1993-01-01)
Antithrombin inhibition using nanobodies to correct bleeding in hemophilia
by: Jamie M O'Sullivan, et al.
Published: (2020-03-01)
by: Jamie M O'Sullivan, et al.
Published: (2020-03-01)
Incidence and features of thrombosis in children with inherited antithrombin deficiency
by: Belén de la Morena-Barrio, et al.
Published: (2019-12-01)
by: Belén de la Morena-Barrio, et al.
Published: (2019-12-01)
Successful use of an antithrombin for heparin resistance with andexanet alfa
by: Jun Honda, et al.
Published: (2023-05-01)
by: Jun Honda, et al.
Published: (2023-05-01)
Physiological significance of antithrombin D-helix interaction with vascular GAGs
by: Indranil Biswas, et al.
Published: (2025-03-01)
by: Indranil Biswas, et al.
Published: (2025-03-01)
Identification of two point mutations associated with inherited antithrombin deficiency
by: Shiue-Wei Lai, et al.
Published: (2024-12-01)
by: Shiue-Wei Lai, et al.
Published: (2024-12-01)
Active antithrombin glycoforms are selectively physiosorbed on plasma extracellular vesicles
by: Annalisa Radeghieri, et al.
Published: (2022-09-01)
by: Annalisa Radeghieri, et al.
Published: (2022-09-01)
Anti-Tumor Functions of Prelatent Antithrombin on Glioblastoma Multiforme Cells
by: Julia Peñas-Martínez, et al.
Published: (2021-05-01)
by: Julia Peñas-Martínez, et al.
Published: (2021-05-01)
Interactions of marine sulfated glycans with antithrombin and platelet factor 4
by: Wenjing Zhang, et al.
Published: (2022-09-01)
by: Wenjing Zhang, et al.
Published: (2022-09-01)
Evaluation of Serum Level of Thrombin-antithrombin III in Preterm Labors
by: Minoo Movahedi, et al.
Published: (2012-03-01)
by: Minoo Movahedi, et al.
Published: (2012-03-01)
Combined life-threatening thromboses and hemorrhages in a patient with afibrinogenemia and antithrombin deficiency
by: S. Le Quellec, et al.
Published: (2018-04-01)
by: S. Le Quellec, et al.
Published: (2018-04-01)
TESTING ANTITHROMBIN LEVEL ALLOWS PREDICTING A CLINICAL OUTCOME OF SEPSIS
by: I. V. Redkin, et al.
Published: (2018-07-01)
by: I. V. Redkin, et al.
Published: (2018-07-01)
Antithrombin III deficiency and idiopathic intracranial hypertension: a case report
by: Mansoureh Togha, et al.
Published: (2025-01-01)
by: Mansoureh Togha, et al.
Published: (2025-01-01)
A successful outcome of pregnancy in a patient with congenital antithrombin deficiency
by: Kovač Mirjana, et al.
Published: (2011-01-01)
by: Kovač Mirjana, et al.
Published: (2011-01-01)
Prognostic Significance of Antithrombin Activity in Patients with Crimean-Congo Hemorrhagic Fever
by: Mustafa Usanmaz, et al.
Published: (2011-08-01)
by: Mustafa Usanmaz, et al.
Published: (2011-08-01)
Effect of endothelium on the anticoagulant activity of a covalent antithrombin-heparin complex
by: Helen M. Atkinson, et al.
Published: (2024-09-01)
by: Helen M. Atkinson, et al.
Published: (2024-09-01)
P1699: ANTITHROMBIN DEFICIENCY IS ASSOCIATED WITH PROTHROMBOTIC FIBRIN CLOT PHENOTYPE
by: M. Zabczyk, et al.
Published: (2022-06-01)
by: M. Zabczyk, et al.
Published: (2022-06-01)
Arterial thrombosis in a patient with nephrotic syndrome and antithrombin Cambrigde II
by: Ana Esther Sirvent, et al.
Published: (2022-11-01)
by: Ana Esther Sirvent, et al.
Published: (2022-11-01)
Thrombin antithrombin complex and IL-18 serum levels in stroke patients
by: Ornella Piazza, et al.
Published: (2010-02-01)
by: Ornella Piazza, et al.
Published: (2010-02-01)
Management of disseminated intravascular coagulation: current insights on antithrombin and thrombomodulin treatments
by: Hayakawa M
Published: (2017-12-01)
by: Hayakawa M
Published: (2017-12-01)
Analysis of blood coagulation in mice: pre-analytical conditions and evaluation of a home-made assay for thrombin-antithrombin complexes
by: Meijers Joost CM, et al.
Published: (2005-08-01)
by: Meijers Joost CM, et al.
Published: (2005-08-01)
Protein C and antithrombin III deficiency in an elderly patient presenting with pulmonary embolism
by: R. Khan, et al.
Published: (2025-08-01)
by: R. Khan, et al.
Published: (2025-08-01)
Comparative study of chromatographic properties of affinity resins in respect of protein of antithrombin III
by: М. А. Аzhigirova, et al.
Published: (2010-04-01)
by: М. А. Аzhigirova, et al.
Published: (2010-04-01)
Similar Items
-
Evaluation of the interference of fitusiran and antithrombin lowering in plasma on routine coagulation assays
by: Ekta Seth Chhabra, et al.
Published: (2025-08-01) -
Antithrombin supplementation to prevent venous thromboembolism: A case of hereditary antithrombin deficiency with increased antithrombin clearance during pregnancy and peripartum
by: Ayako Kaneda-Takeuchi, et al.
Published: (2025-06-01) -
Comparison of antithrombin activity assays in detection of patients with heparin binding site antithrombin deficiency: systematic review and meta-analysis
by: Tamara Rojnik, et al.
Published: (2023-10-01) -
SAFETY AND EFFICACY OF THE FITUSIRAN REVISED ANTITHROMBIN-BASED DOSE REGIMEN IN PEOPLE WITH HAEMOPHILIA A OR B, WITH OR WITHOUT INHIBITORS (ATLAS-OLE)
by: Guy-Young, et al.
Published: (2024-10-01) -
Successful administration of recombinant human antithrombin in a pregnant Japanese woman with hereditary antithrombin deficiency
by: Yuya Fujibe, et al.
Published: (2019-11-01)
