Case series of rhinocerebral mucormycosis occurring in diabetic patients

Background: Rhinocerebral mucormycosis is a fatal infection typically affecting diabetic or immunosuppressed patients. In most cases, infection is caused by inhalation of fungal spores. Mortality rate of patients is very high (40-85%).  Case Presentation: In this study, three diabetic patients with...

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Bibliographic Details
Published in:Caspian Journal of Internal Medicine
Main Authors: Rasoul Mohammadi, Mohsen Meidani, Kamyar Mostafavizadeh, Bijan Iraj, Pooria Hamedani, Mohammad Amin Sayedain, Mojgan Mokhtari
Format: Article
Language:English
Published: Babol University of Medical Sciences 2015-10-01
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Online Access:http://caspjim.com/browse.php?a_code=A-10-329-1&slc_lang=en&sid=1
Description
Summary:Background: Rhinocerebral mucormycosis is a fatal infection typically affecting diabetic or immunosuppressed patients. In most cases, infection is caused by inhalation of fungal spores. Mortality rate of patients is very high (40-85%).  Case Presentation: In this study, three diabetic patients with rhinocerebral mucormycosis were presented. The etiologic agents of mucormycosis in two patients were isolated and identified by sequence analysis and data were registered in Gene bank database.  Conclusion: In patients with mucormeosis, early detection, surgical excision and appropriate debridement, suitable antifungal therapy, and control of risk factors like diabetes mellitus are the main parameters of successful management of this lethal infection.
ISSN:2008-6164
2008-6172