5-[2-(4-Chlorophenyl)-2-oxoethyl]-3-(4-hydroxyphenyl)-2-thioxo-1,3-thiazolidin-4-one
Rhodanine derivatives, as a subtype of thiazolidin-4-ones, represent an important class of heterocyclic compound known for their broad spectrum of biological activities and practical applications. In this short note, the synthesis of a new compound, 5-[2-(4-chlorophenyl)-2-oxoethyl]-3-(4-hydroxyphen...
| Published in: | Molbank |
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| Main Author: | |
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2025-08-01
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| Subjects: | |
| Online Access: | https://www.mdpi.com/1422-8599/2025/3/M2049 |
| Summary: | Rhodanine derivatives, as a subtype of thiazolidin-4-ones, represent an important class of heterocyclic compound known for their broad spectrum of biological activities and practical applications. In this short note, the synthesis of a new compound, 5-[2-(4-chlorophenyl)-2-oxoethyl]-3-(4-hydroxyphenyl)-2-thioxo-1,3-thiazolidin-4-one, is described. The target molecule was synthesized via a thia-Michael addition followed by cyclocondensation. Its structure was confirmed by <sup>1</sup>H and <sup>13</sup>C NMR spectroscopy and further supported by 2D NMR studies. |
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| ISSN: | 1422-8599 |