The chylomicron saga: time to focus on postprandial metabolism
Since statins have had such tremendous therapeutic success over the last three decades, the field of atherosclerosis has become somewhat LDL-centric, dismissing the relevance of triglycerides (TG), particularly chylomicrons, in atherogenesis. Nonetheless, 50% of patients who take statins are at risk...
| Published in: | Frontiers in Endocrinology |
|---|---|
| Main Author: | Alejandro Gugliucci |
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2024-01-01
|
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fendo.2023.1322869/full |
Similar Items
Apolipoprotein CIII may mediate the impacts of angiopoietin-like protein 8 on triglyceride metabolism
by: Mengdie Luo, et al.
Published: (2018-07-01)
by: Mengdie Luo, et al.
Published: (2018-07-01)
Editorial: TRLs (triglycerides-rich lipoproteins): a new target for atherosclerosis
by: Mei Dong, et al.
Published: (2025-01-01)
by: Mei Dong, et al.
Published: (2025-01-01)
Elevated Levels of Apolipoprotein CIII Increase the Risk of Postprandial Hypertriglyceridemia
by: Yunpeng Guan, et al.
Published: (2021-04-01)
by: Yunpeng Guan, et al.
Published: (2021-04-01)
Moderate-intensity continuous training reduces triglyceridemia and improves oxygen consumption in dyslipidemic apoCIII transgenic mice
by: N.R. Teixeira Junior, et al.
Published: (2024-07-01)
by: N.R. Teixeira Junior, et al.
Published: (2024-07-01)
Identification of the HDL-ApoCIII to VLDL-ApoCIII ratio as a predictor of coronary artery disease in the general population: The Chin-Shan Community Cardiovascular Cohort (CCCC) study in Taiwan
by: Chang Po-Yuan, et al.
Published: (2012-11-01)
by: Chang Po-Yuan, et al.
Published: (2012-11-01)
The ANGPTL3-4-8 model, a molecular mechanism for triglyceride trafficking
by: Ren Zhang
Published: (2016-01-01)
by: Ren Zhang
Published: (2016-01-01)
Genetic and functional studies of the LMF1 gene in Thai patients with severe hypertriglyceridemia
by: Wanee Plengpanich, et al.
Published: (2020-06-01)
by: Wanee Plengpanich, et al.
Published: (2020-06-01)
Characterization of sexual dimorphism in ANGPTL4 levels and function
by: Mingjuan Deng, et al.
Published: (2024-04-01)
by: Mingjuan Deng, et al.
Published: (2024-04-01)
The Importance of Lipoprotein Lipase Regulation in Atherosclerosis
by: Anni Kumari, et al.
Published: (2021-07-01)
by: Anni Kumari, et al.
Published: (2021-07-01)
Modeling the postprandial CETP-mediated lipid redistribution between chylomicrons, LDL and HDL
by: Martin Jansen, et al.
Published: (2025-07-01)
by: Martin Jansen, et al.
Published: (2025-07-01)
New insights into ANGPLT3 in controlling lipoprotein metabolism and risk of cardiovascular diseases
by: Xin Su, et al.
Published: (2018-01-01)
by: Xin Su, et al.
Published: (2018-01-01)
Remnant lipoproteins are related to intima-media thickness of the carotid artery independently of LDL cholesterol and plasma triglycerides
by: Fredrik Karpe, et al.
Published: (2001-01-01)
by: Fredrik Karpe, et al.
Published: (2001-01-01)
Enhanced atherosclerosis in apolipoprotein E knockout rabbits: role of apoB48-rich remnant lipoproteins
by: Manabu Niimi, et al.
Published: (2024-07-01)
by: Manabu Niimi, et al.
Published: (2024-07-01)
Consumption of low doses of fat prevents the postprandial rise in chylomicron particle concentration and remnant accumulation in healthy normolipidaemic males
by: Anthony P. James, et al.
Published: (2012-07-01)
by: Anthony P. James, et al.
Published: (2012-07-01)
Delayed clearance of postprandial large TG-rich particles in normolipidemic carriers of LPL Asn291Ser gene variant
by: Niina Mero, et al.
Published: (1999-09-01)
by: Niina Mero, et al.
Published: (1999-09-01)
Characterization of the lipolytic activity of endothelial lipase
by: Mary G. McCoy, et al.
Published: (2002-06-01)
by: Mary G. McCoy, et al.
Published: (2002-06-01)
Pre-operative levels of angiopoietin protein-like 3 (ANGPTL3) in women diagnosed with high-grade serous carcinoma of the ovary
by: Emilie Wong Chong, et al.
Published: (2024-02-01)
by: Emilie Wong Chong, et al.
Published: (2024-02-01)
Intestine-specific MTP and global ACAT2 deficiency lowers acute cholesterol absorption with chylomicrons and HDLs
by: Jahangir Iqbal, et al.
Published: (2014-11-01)
by: Jahangir Iqbal, et al.
Published: (2014-11-01)
Elevated angiopoietin-like protein 3 serum levels in diabetic nephropathy patients and its association with renal function and lipid profile
by: Samaneh Mohassel Azadi, et al.
Published: (2023-06-01)
by: Samaneh Mohassel Azadi, et al.
Published: (2023-06-01)
Post-prandial lipaemia and endothelial function among healthy men
by: G Sutsch, et al.
Published: (2001-04-01)
by: G Sutsch, et al.
Published: (2001-04-01)
Mathematical Modelling of Material Transfer to High-Density Lipoprotein (HDL) upon Triglyceride Lipolysis by Lipoprotein Lipase: Relevance to Cardioprotective Role of HDL
by: Svetlana Schekatolina, et al.
Published: (2022-07-01)
by: Svetlana Schekatolina, et al.
Published: (2022-07-01)
Peroxisome proliferator-activated receptor α polymorphisms and postprandial lipemia in healthy men
by: Toshiko Tanaka, et al.
Published: (2007-07-01)
by: Toshiko Tanaka, et al.
Published: (2007-07-01)
Activation of VEGFR3 and MLC2 are Critical for GLP-2 Enhancement of Chylomicron Transport
by: Lili Tian, et al.
Published: (2025-01-01)
by: Lili Tian, et al.
Published: (2025-01-01)
Plasma apolipoprotein AV levels in mice are positively associated with plasma triglyceride levels
by: S.F.C. Vaessen, et al.
Published: (2009-05-01)
by: S.F.C. Vaessen, et al.
Published: (2009-05-01)
Particle size and composition of dog lymph chylomicrons
by: Akira Yokoyama, et al.
Published: (1965-04-01)
by: Akira Yokoyama, et al.
Published: (1965-04-01)
Competitive displacement of lipoprotein lipase from heparan sulfate is orchestrated by a disordered acidic cluster in GPIHBP1
by: Anamika Biswas, et al.
Published: (2025-02-01)
by: Anamika Biswas, et al.
Published: (2025-02-01)
apoA-IV tagged with the ER retention signal KDEL perturbs the intracellular trafficking and secretion of apoB
by: James W. Gallagher, et al.
Published: (2004-10-01)
by: James W. Gallagher, et al.
Published: (2004-10-01)
Cholesterol esterification by ACAT2 is essential for efficient intestinal cholesterol absorption: evidence from thoracic lymph duct cannulation[S]
by: Tam M. Nguyen, et al.
Published: (2012-01-01)
by: Tam M. Nguyen, et al.
Published: (2012-01-01)
Decoding the role of angiopoietin-like protein 4/8 complex–mediated plasmin generation in the regulation of LPL activity
by: Yan Q. Chen, et al.
Published: (2023-10-01)
by: Yan Q. Chen, et al.
Published: (2023-10-01)
APOA5 deficiency causes hypertriglyceridemia by reducing amounts of lipoprotein lipase in capillaries
by: Ye Yang, et al.
Published: (2024-07-01)
by: Ye Yang, et al.
Published: (2024-07-01)
Role of Endothelial Cell Lipoprotein Lipase for Brown Adipose Tissue Lipid and Glucose Handling
by: Ellen Thiemann, et al.
Published: (2022-03-01)
by: Ellen Thiemann, et al.
Published: (2022-03-01)
Omega-3 fatty acids eicosapentaenoic acid and docosahexaenoic acid and their mechanisms of action on apolipoprotein B-containing lipoproteins in humans: a review
by: Jan Oscarsson, et al.
Published: (2017-08-01)
by: Jan Oscarsson, et al.
Published: (2017-08-01)
Reduced Capacity of High‐Density Lipoprotein to Acquire Free Cholesterol From Triglyceride‐Rich Lipoproteins Is Associated With Elevated Postprandial Hypertriglyceridemia in Healthy Men
by: Sophie Galier, et al.
Published: (2024-08-01)
by: Sophie Galier, et al.
Published: (2024-08-01)
Multilayer regulation of postprandial triglyceride metabolism in response to acute cold exposure
by: Yiliang Zhang, et al.
Published: (2025-03-01)
by: Yiliang Zhang, et al.
Published: (2025-03-01)
Chylomicron remnants are increased in the postprandial state in CD36 deficiency
by: Daisaku Masuda, et al.
Published: (2009-05-01)
by: Daisaku Masuda, et al.
Published: (2009-05-01)
Oligomerization state-dependent hyperlipidemic effect of angiopoietin-like protein 4
by: Hongfei Ge, et al.
Published: (2004-11-01)
by: Hongfei Ge, et al.
Published: (2004-11-01)
Fasting, non-fasting and postprandial triglycerides for screening cardiometabolic risk
by: Bryant H. Keirns, et al.
Published: (2021-01-01)
by: Bryant H. Keirns, et al.
Published: (2021-01-01)
Differences and similarities of postprandial lipemia in rodents and humans
by: da Silva Lívia R, et al.
Published: (2011-05-01)
by: da Silva Lívia R, et al.
Published: (2011-05-01)
GPIHBP1 and ANGPTL4 Utilize Protein Disorder to Orchestrate Order in Plasma Triglyceride Metabolism and Regulate Compartmentalization of LPL Activity
by: Kristian Kølby Kristensen, et al.
Published: (2021-07-01)
by: Kristian Kølby Kristensen, et al.
Published: (2021-07-01)
Angiopoietin-Like Protein Family-Mediated Functions in Modulating Triglyceride Metabolism and Related Metabolic Diseases
by: Sen Yang, et al.
Published: (2025-03-01)
by: Sen Yang, et al.
Published: (2025-03-01)
Similar Items
-
Apolipoprotein CIII may mediate the impacts of angiopoietin-like protein 8 on triglyceride metabolism
by: Mengdie Luo, et al.
Published: (2018-07-01) -
Editorial: TRLs (triglycerides-rich lipoproteins): a new target for atherosclerosis
by: Mei Dong, et al.
Published: (2025-01-01) -
Elevated Levels of Apolipoprotein CIII Increase the Risk of Postprandial Hypertriglyceridemia
by: Yunpeng Guan, et al.
Published: (2021-04-01) -
Moderate-intensity continuous training reduces triglyceridemia and improves oxygen consumption in dyslipidemic apoCIII transgenic mice
by: N.R. Teixeira Junior, et al.
Published: (2024-07-01) -
Identification of the HDL-ApoCIII to VLDL-ApoCIII ratio as a predictor of coronary artery disease in the general population: The Chin-Shan Community Cardiovascular Cohort (CCCC) study in Taiwan
by: Chang Po-Yuan, et al.
Published: (2012-11-01)
