Applying Natural Language Processing to ClinicalTrials.gov: mRNA cancer vaccine case study

Abstract Recently, biotechnology and pharmaceutical industries have made strides to adopt and implement Natural Language Processing (NLP) to address challenges faced when extracting and synthesizing high volumes of information found in unstructured and semistructured text. Here we present, and provi...

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Published in:Clinical and Translational Science
Main Authors: Bianca Vora, Denison Kuruvilla, Chloe Kim, Michael Wu, Colby S. Shemesh, Gillie A. Roth
Format: Article
Language:English
Published: Wiley 2023-12-01
Online Access:https://doi.org/10.1111/cts.13648
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author Bianca Vora
Denison Kuruvilla
Chloe Kim
Michael Wu
Colby S. Shemesh
Gillie A. Roth
author_facet Bianca Vora
Denison Kuruvilla
Chloe Kim
Michael Wu
Colby S. Shemesh
Gillie A. Roth
author_sort Bianca Vora
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container_title Clinical and Translational Science
description Abstract Recently, biotechnology and pharmaceutical industries have made strides to adopt and implement Natural Language Processing (NLP) to address challenges faced when extracting and synthesizing high volumes of information found in unstructured and semistructured text. Here we present, and provide a summary of the findings from, a use case where NLP and text mining methodologies were used to extract clinical trial data from ClinicalTrials.gov for mRNA cancer vaccines.
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spelling doaj-art-7ef953fbeeb640889dffb00922151dc42025-08-19T21:45:11ZengWileyClinical and Translational Science1752-80541752-80622023-12-0116122417242010.1111/cts.13648Applying Natural Language Processing to ClinicalTrials.gov: mRNA cancer vaccine case studyBianca Vora0Denison Kuruvilla1Chloe Kim2Michael Wu3Colby S. Shemesh4Gillie A. Roth5Clinical Pharmacology Genentech, Inc. South San Francisco California USAClinical Pharmacology Genentech, Inc. South San Francisco California USAComputational Sciences Genentech, Inc. South San Francisco California USAComputational Sciences Genentech, Inc. South San Francisco California USAClinical Pharmacology Genentech, Inc. South San Francisco California USAPreclinical and Translational PKPD Genentech, Inc. South San Francisco California USAAbstract Recently, biotechnology and pharmaceutical industries have made strides to adopt and implement Natural Language Processing (NLP) to address challenges faced when extracting and synthesizing high volumes of information found in unstructured and semistructured text. Here we present, and provide a summary of the findings from, a use case where NLP and text mining methodologies were used to extract clinical trial data from ClinicalTrials.gov for mRNA cancer vaccines.https://doi.org/10.1111/cts.13648
spellingShingle Bianca Vora
Denison Kuruvilla
Chloe Kim
Michael Wu
Colby S. Shemesh
Gillie A. Roth
Applying Natural Language Processing to ClinicalTrials.gov: mRNA cancer vaccine case study
title Applying Natural Language Processing to ClinicalTrials.gov: mRNA cancer vaccine case study
title_full Applying Natural Language Processing to ClinicalTrials.gov: mRNA cancer vaccine case study
title_fullStr Applying Natural Language Processing to ClinicalTrials.gov: mRNA cancer vaccine case study
title_full_unstemmed Applying Natural Language Processing to ClinicalTrials.gov: mRNA cancer vaccine case study
title_short Applying Natural Language Processing to ClinicalTrials.gov: mRNA cancer vaccine case study
title_sort applying natural language processing to clinicaltrials gov mrna cancer vaccine case study
url https://doi.org/10.1111/cts.13648
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