Identification and preclinical efficacy evaluation of two lytic bacteriophages targeting highly virulent and multidrug-resistant Klebsiella pneumoniae

Abstract Background The emergence of MDR K. pneumoniae poses a critical challenge in treating respiratory-associated pneumonia. Bacteriophages are promising antibiotic alternatives with unique features. This study aimed to isolate new bacteriophages from the hospital environment and investigate thei...

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التفاصيل البيبلوغرافية

الحاوية / القاعدة:	Annals of Clinical Microbiology and Antimicrobials
المؤلفون الرئيسيون:	Ai Guo, Dianbao Zuo, Li Shi, Ming Guo, Jinquan Li, Caili Li, Puqing Wang, Xiaodong Sun, Ming Sang
التنسيق:	مقال
اللغة:	الإنجليزية
منشور في:	BMC 2025-08-01
الموضوعات:	Lytic bacteriophage Multidrug-resistant Klebsiella pneumoniae Bacteriophage therapy Biofilm degradation Histopathology
الوصول للمادة أونلاين:	https://doi.org/10.1186/s12941-025-00812-9