Integrating Strategy of Network Pharmacology, Molecular Dynamics Simulation, and Experimental Verification to Investigate the Potential Mechanism of <i>Gastrodia elata</i> Against Alcoholic Liver Injury

As one of the medicinal and edible resources, <i>Gastrodia elata</i> (GE) is considered to hold potential in alleviating alcoholic liver injury, yet its mechanism needs further elucidation. To explore the molecular mechanisms of GE against alcoholic liver injury, network pharmacology, mo...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:	Foods
المؤلفون الرئيسيون:	Peiyuan Sun, Ruohan Zhang, Xuanyou Li, Dengwang Yang, Shunfeng Ji, Lei Peng, Jun Sheng, Jing Wang
التنسيق:	مقال
اللغة:	الإنجليزية
منشور في:	MDPI AG 2025-06-01
الموضوعات:	<i>Gastrodia elata</i> alcoholic liver injury network pharmacology molecular dynamics simulation cell experiment molecular mechanism
الوصول للمادة أونلاين:	https://www.mdpi.com/2304-8158/14/12/2008

مواد مشابهة

Analyzing of the Composition and Medicinal Properties of Gastrodia elata during Cooking Based on Metabonomics and Network Pharmacology
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منشور في: (2023-02-01)

A novel alcohol steamed preparation from Gastrodia elata Blume: Pharmacological assessment of a functional food
حسب: Lijun Cheng, وآخرون
منشور في: (2023-03-01)

Transformation Mechanisms of Chemical Ingredients in Steaming Process of <i>Gastrodia elata</i> Blume
حسب: Yun Li, وآخرون
منشور في: (2019-08-01)

Integrative Transcriptomic and Metabolomic Analysis Reveals Regulatory Networks and Metabolite Dynamics in <i>Gastrodia elata</i> Flower Development
حسب: Hongyu Chen, وآخرون
منشور في: (2025-02-01)

Gastrodia elata Bl. f. cyaneum L. B. Lin: A new form of Gastrodia (Orchidaceae) in Yunnan
حسب: LIU Jiajia, وآخرون
منشور في: (2024-11-01)

Structural Characterization of a Polysaccharide from <i>Gastrodia elata</i> and Its Bioactivity on Gut Microbiota
حسب: Jiangyan Huo, وآخرون
منشور في: (2021-07-01)

Research progress of Gastrodia elata Blume polysaccharides: a review of chemical structures and biological activities
حسب: Liu Yang, وآخرون
منشور في: (2024-07-01)

Neuropharmacological effects of Gastrodia elata Blume and its active ingredients
حسب: Dong Wang, وآخرون
منشور في: (2025-04-01)

Hierarchical Detection of <i>Gastrodia elata</i> Based on Improved YOLOX
حسب: Xingwei Duan, وآخرون
منشور في: (2023-05-01)

The complete chloroplast genome of Korean Gastrodia elata Blume
حسب: Min-Jeong Kang, وآخرون
منشور في: (2020-01-01)

Integrated transcriptome and metabolome provide insight into phenolics and soluble sugar variation in the different varieties of Gastrodia elata Blume from different areas in China
حسب: Haixia Wang, وآخرون
منشور في: (2025-09-01)

Chemical composition and nutritional properties of Gastrodia elata water extract and its effects in rats with streptozotocin–induced diabetic osteoporosis
حسب: Fanfan Jia, وآخرون
منشور في: (2025-06-01)

<i>Clonostachys rosea</i>, a Pathogen of Brown Rot in <i>Gastrodia elata</i> in China
حسب: Huan Yao, وآخرون
منشور في: (2024-09-01)

Effect of Kombucha Consortium Fermentation on Active Ingredients and Sensory Quality of Gastrodia elata
حسب: WANG Ying, DONG Mingsheng, ZHANG Guoqiang, HAN Yuefeng
منشور في: (2024-02-01)

The effects of Gastrodia elata on anxiety-like behavior in mice
حسب: Lan-Qiao He, وآخرون
منشور في: (2024-12-01)

A complete chloroplast genome sequence of Gastrodia elata (Orchidaceae) represents high sequence variation in the species
حسب: Jongsun Park, وآخرون
منشور في: (2020-01-01)

Exploring the Anti-inflammatory Components of Gastrodia elata B1 and Their Action Mechanism Based on UPLC-Q-TOF-MS/MS and Network Pharmacology
حسب: XU Ningmeng, DONG Shihao, QIN Fen, SHEN Kaize, LI Weilan, HUA Yan, GUO Lei
منشور في: (2025-02-01)

Application of Gastrodia elata in Functional Food in China
حسب: Hao DUAN, وآخرون
منشور في: (2023-05-01)

Comparative analysis of the multi-element and pharmacological composition of Gastrodia elata blume from different geographic origins
حسب: Yujie Shang, وآخرون
منشور في: (2025-08-01)

The Mixture of <i>Gastrodia elata</i> and <i>Glycyrrhiza uralensis</i> Attenuates Scopolamine-Induced Cognitive Disorder
حسب: Ji-Hyun Lee, وآخرون
منشور في: (2023-03-01)

Analysis of Suitable Cultivation Sites for <i>Gastrodia elata</i> Using GIS: A Comparison of Various Classification Methods
حسب: Gyeongmi Tak, وآخرون
منشور في: (2025-02-01)

Whole genome sequencing and analysis of the symbiotic Armillaria gallica M3 with Gastrodia elata
حسب: Cheng-Ying Luo, وآخرون
منشور في: (2025-03-01)

Features of bacterial and fungal communities in the rhizosphere of Gastrodia elata cultivated in greenhouse for early harvest
حسب: Nguyen Van Khanh, وآخرون
منشور في: (2024-04-01)

Gastrodinol derivatives and prenylated flavones from the flower branch of Gastrodia elata
حسب: Shi-Hui Qin, وآخرون
منشور في: (2024-03-01)

Gastrodia elata rhizoma ameliorates thioacetamide-induced liver injury in dogs
حسب: Hye-Bin Yoon, وآخرون
منشور في: (2023-06-01)

Insight into Medicinal Chemistry Behind Traditional Chinese Medicines: p-Hydroxybenzyl Alcohol-Derived Dimers and Trimers from Gastrodia elata
حسب: Yanan Wang, وآخرون
منشور في: (2020-08-01)

GelFAP v2.0: an improved platform for Gene functional analysis in Gastrodia elata
حسب: Jiaotong Yang, وآخرون
منشور في: (2023-04-01)

Global metabolic profile and multiple phytometabolites in the different varieties of Gastrodia elata Blume
حسب: Xu Zeng, وآخرون
منشور في: (2023-10-01)

Optimization of Fermentation Processing of Gastrodia elata Oral Liquid with Lactic Acid Bacteria
حسب: Laifeng CHEN, وآخرون
منشور في: (2023-08-01)

Effect of Ultra-High-Pressure Treatment on <i>Gastrodia elata</i> Blume: Drying Characteristics, Components, and Neuroprotective Activity
حسب: Hongjing Dong, وآخرون
منشور في: (2024-11-01)

Influence of Introduction and Cultivation on the Content of Active Ingredients and Elements in Gastrodia elata
حسب: Weijin HUANG, وآخرون
منشور في: (2025-04-01)

Impact of climate change on the geographical distribution and niche dynamics of Gastrodia elata
حسب: Juan Hu, وآخرون
منشور في: (2023-07-01)

Ameliorative Effect of Gastrodia elata Vinegar on Glucose and Lipid Metabolism Disorders in Obese Mice
حسب: WANG Wenqi, JIANG Yuchen, LIU Jiahua, ZHANG Chi, HE Yang, WEN Liankui
منشور في: (2025-08-01)

Examination of the Research and Development Patterns of Gastrodia Elata Food using Literature and Patent Data
حسب: FENG Ming-ke, وآخرون
منشور في: (2025-05-01)

Design, synthesis and neuroprotective activity of compound derived from Gastrodia elata Blume and borneol
حسب: Lijuan Zhi, وآخرون
منشور في: (2024-09-01)

Neuroprotective Effect of the Mixture of <i>Gastrodiae elata</i> and <i>Glycyrrhizae uralensis</i> In Vitro
حسب: Su-Ha Hwang, وآخرون
منشور في: (2022-12-01)

Targeting Oxidative Stress and Neuro-Inflammation by Gastrodia elata Improves Disease Outcomes in a Rat Model of Epilepsy
حسب: Noor-Alhuda Mohammed Alebadi, وآخرون
منشور في: (2025-01-01)

Assessment of the Effects of Structural Modification of <i>Gastrodia elata</i> Polysaccharide on Anti-Breast Cancer Activity Using Asymmetrical Flow Field-Flow Fractionation
حسب: Xiaoying Liu, وآخرون
منشور في: (2023-06-01)

Constituents of <i>Gastrodia elata</i> and Their Neuroprotective Effects in HT22 Hippocampal Neuronal, R28 Retinal Cells, and BV2 Microglial Cells
حسب: Hye Mi Kim, وآخرون
منشور في: (2020-08-01)

Improvement effect of Gastrodia elata and Ganoderma lucidum Jiaosu on insomnia mice induced by p-chlorophenylalanine
حسب: YAN Mei, LANG Rui, PENG Mei, LI Lilang, GAO Ming, YANG Juan, LUO Xianghua, YANG Xiaosheng, WANG Yu
منشور في: (2025-08-01)