Genome-wide discovered psychosis-risk gene ZNF804A impacts on white matter microstructure in health, schizophrenia and bipolar disorder

Background. Schizophrenia (SZ) and bipolar disorder (BD) have both been associated with reduced microstructural white matter integrity using, as a proxy, fractional anisotropy (FA) detected using diffusion tensor imaging (DTI). Genetic susceptibility for both illnesses has also been positively corre...

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Bibliographic Details
Published in:PeerJ
Main Authors: Emma-Jane Mallas, Francesco Carletti, Christopher A. Chaddock, James Woolley, Marco M. Picchioni, Sukhwinder S. Shergill, Fergus Kane, Matthew P.G. Allin, Gareth J. Barker, Diana P. Prata
Format: Article
Language:English
Published: PeerJ Inc. 2016-02-01
Subjects:
Genome-wide association
White matter
ZNF804A
Psychosis
Fractional anisotropy
Diffusion tensor imaging
Online Access:https://peerj.com/articles/1570.pdf

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