Diagnostic insights into disseminated histoplasmosis: a case report highlighting bone marrow analysis

We present a case of a 43-year-old immunocompromised female patient diagnosed with disseminated histoplasmosis on bone marrow examination, at clinical laboratory of Kasturba Hospital, Manipal, Karnataka, India. The patient, presenting with symptoms like weight loss, appetite loss, and pancytopenia,...

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Bibliographic Details
Published in:Iranian Journal of Microbiology
Main Authors: Vaanya Kaushik, Ruchee Khanna, Vinay Khanna, Muralidhar Varma
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2024-02-01
Subjects:
Histoplasmosis;
HIV infection;
Opportunistic infection;
Pancytopenia;
Bone marrow examination
Online Access:https://ijm.tums.ac.ir/index.php/ijm/article/view/4434
Description
Summary:We present a case of a 43-year-old immunocompromised female patient diagnosed with disseminated histoplasmosis on bone marrow examination, at clinical laboratory of Kasturba Hospital, Manipal, Karnataka, India. The patient, presenting with symptoms like weight loss, appetite loss, and pancytopenia, underwent bone marrow aspiration and biopsy. The bone marrow studies revealed HIV-associated changes and the yeast form of Histoplasma capsulatum, confirming disseminated histoplasmosis. Bone marrow examination is highlighted as a diagnostic tool with significant sensitivity in such cases. The report stresses on the importance of awareness and early diagnosis of histoplasmosis in immunocompromised patients, given its potential lethality and the need for timely therapeutic intervention for better prognosis.
ISSN:2008-3289
2008-4447

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