Mechanism and treatment progress of disseminated intravascular coagulation in sepsis

Sepsis is the main cause of death in critically ill patients in clinic, with high incidence and complicated pathogenesis. Coagulation system is an important factor of the pathogenesis and lethal mechanism of sepsis, especially sepsis complicated with disseminated intravascular coagulation (DIC), whi...

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Bibliographic Details
Published in:Zhongguo linchuang yanjiu
Main Author: ZHANG Jun, FENG Jianhong, DU Xianrong
Format: Article
Language:Chinese
Published: The Editorial Department of Chinese Journal of Clinical Research 2024-11-01
Subjects:
sepsis， coagulation system， disseminated intravascular coagulation， tissue factor， neutrophil extracellular trap
Online Access:http://zglcyj.ijournals.cn/zglcyj/ch/reader/create_pdf.aspx?file_no=20241105
Description
Summary:Sepsis is the main cause of death in critically ill patients in clinic, with high incidence and complicated pathogenesis. Coagulation system is an important factor of the pathogenesis and lethal mechanism of sepsis, especially sepsis complicated with disseminated intravascular coagulation (DIC), which is the dual effect of coagulation cascade reaction and inflammatory immune response. This paper describes the molecular mechanism and the latest treatment research progress of DIC in sepsis, in order to provide new ideas and methods for clinical work.
ISSN:1674-8182

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