Experimental Models to Study the Pathogenesis and Treatment of Mucormycosis
Mucormycosis presents a formidable challenge to clinicians and researchers. Animal models are an essential part of the effort to decipher the pathogenesis of mucormycosis and to develop novel pharmacotherapeutics against it. Diverse model systems have been established, using a range of animal hosts,...
| Published in: | Journal of Fungi |
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| Main Author: | |
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2024-01-01
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| Subjects: | |
| Online Access: | https://www.mdpi.com/2309-608X/10/1/85 |
| _version_ | 1849989626484228096 |
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| author | Ronen Ben-Ami |
| author_facet | Ronen Ben-Ami |
| author_sort | Ronen Ben-Ami |
| collection | DOAJ |
| container_title | Journal of Fungi |
| description | Mucormycosis presents a formidable challenge to clinicians and researchers. Animal models are an essential part of the effort to decipher the pathogenesis of mucormycosis and to develop novel pharmacotherapeutics against it. Diverse model systems have been established, using a range of animal hosts, immune and metabolic perturbations, and infection routes. An understanding of the characteristics, strengths, and drawbacks of these models is needed to optimize their use for specific research aims. |
| format | Article |
| id | doaj-art-85c19fc301e240d1bfbdec2a9ae89f7b |
| institution | Directory of Open Access Journals |
| issn | 2309-608X |
| language | English |
| publishDate | 2024-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| spelling | doaj-art-85c19fc301e240d1bfbdec2a9ae89f7b2025-08-20T00:54:18ZengMDPI AGJournal of Fungi2309-608X2024-01-011018510.3390/jof10010085Experimental Models to Study the Pathogenesis and Treatment of MucormycosisRonen Ben-Ami0Department of Infectious Diseases, Tel Aviv Sourasky Medical Center, Faculty of Medicine, Tel Aviv University, Tel Aviv 64239, IsraelMucormycosis presents a formidable challenge to clinicians and researchers. Animal models are an essential part of the effort to decipher the pathogenesis of mucormycosis and to develop novel pharmacotherapeutics against it. Diverse model systems have been established, using a range of animal hosts, immune and metabolic perturbations, and infection routes. An understanding of the characteristics, strengths, and drawbacks of these models is needed to optimize their use for specific research aims.https://www.mdpi.com/2309-608X/10/1/85mucormycosismodelsanimalvirulencediabetic ketoacidosis |
| spellingShingle | Ronen Ben-Ami Experimental Models to Study the Pathogenesis and Treatment of Mucormycosis mucormycosis models animal virulence diabetic ketoacidosis |
| title | Experimental Models to Study the Pathogenesis and Treatment of Mucormycosis |
| title_full | Experimental Models to Study the Pathogenesis and Treatment of Mucormycosis |
| title_fullStr | Experimental Models to Study the Pathogenesis and Treatment of Mucormycosis |
| title_full_unstemmed | Experimental Models to Study the Pathogenesis and Treatment of Mucormycosis |
| title_short | Experimental Models to Study the Pathogenesis and Treatment of Mucormycosis |
| title_sort | experimental models to study the pathogenesis and treatment of mucormycosis |
| topic | mucormycosis models animal virulence diabetic ketoacidosis |
| url | https://www.mdpi.com/2309-608X/10/1/85 |
| work_keys_str_mv | AT ronenbenami experimentalmodelstostudythepathogenesisandtreatmentofmucormycosis |