The role of the “gut microbiota-mitochondria” crosstalk in the pathogenesis of multiple sclerosis
Multiple Sclerosis (MS) is a neurologic autoimmune disease whose exact pathophysiologic mechanisms remain to be elucidated. Recent studies have shown that the onset and progression of MS are associated with dysbiosis of the gut microbiota. Similarly, a large body of evidence suggests that mitochondr...
| Published in: | Frontiers in Microbiology |
|---|---|
| Main Authors: | Huan Tian, Dunbing Huang, Jiaqi Wang, Huaqiang Li, Jiaxin Gao, Yue Zhong, Libin Xia, Anren Zhang, Zhonghua Lin, Xiaohua Ke |
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2024-04-01
|
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fmicb.2024.1404995/full |
Similar Items
The Crosstalk between the Gut Microbiota and Mitochondria during Exercise
by: Allison Clark, et al.
Published: (2017-05-01)
by: Allison Clark, et al.
Published: (2017-05-01)
The complexities of investigating mitochondria dynamics in multiple sclerosis and mouse models of MS
by: Kelley C. Atkinson, et al.
Published: (2023-07-01)
by: Kelley C. Atkinson, et al.
Published: (2023-07-01)
Understanding the Holobiont: Crosstalk Between Gut Microbiota and Mitochondria During Long Exercise in Horse
by: Núria Mach, et al.
Published: (2021-04-01)
by: Núria Mach, et al.
Published: (2021-04-01)
Gut microbiota: a novel strategy affecting atherosclerosis
by: Lingshuang Yang, et al.
Published: (2025-08-01)
by: Lingshuang Yang, et al.
Published: (2025-08-01)
Amyotrophic Lateral Sclerosis (ALS): Stressed by Dysfunctional Mitochondria-Endoplasmic Reticulum Contacts (MERCs)
by: Junsheng Chen, et al.
Published: (2021-07-01)
by: Junsheng Chen, et al.
Published: (2021-07-01)
Oxidative Stress, Neuroinflammation and Mitochondria in the Pathophysiology of Amyotrophic Lateral Sclerosis
by: Elena Obrador, et al.
Published: (2020-09-01)
by: Elena Obrador, et al.
Published: (2020-09-01)
Relationships between systemic sclerosis and atherosclerosis: screening for mitochondria-related biomarkers
by: Fei Wang, et al.
Published: (2024-07-01)
by: Fei Wang, et al.
Published: (2024-07-01)
Feeding the gut microbiome: impact on multiple sclerosis
by: Matteo Bronzini, et al.
Published: (2023-05-01)
by: Matteo Bronzini, et al.
Published: (2023-05-01)
Advances in the Mechanism and Regulation of Obesity Induced by Gut Microbiota
by: YU Miao, XU Jinzhao, YANG Xiaoying, MA Longkai, YU Yansong, NING Ke, XIE Qinggang, XU Xiaoxi
Published: (2023-08-01)
by: YU Miao, XU Jinzhao, YANG Xiaoying, MA Longkai, YU Yansong, NING Ke, XIE Qinggang, XU Xiaoxi
Published: (2023-08-01)
Decoding ischemic stroke: Perspectives on the endoplasmic reticulum, mitochondria, and their crosstalk
by: Chuxin Zhang, et al.
Published: (2025-05-01)
by: Chuxin Zhang, et al.
Published: (2025-05-01)
Editorial: Crosstalk of Mitochondria With Brain Insulin and Leptin Signaling
by: André Kleinridders, et al.
Published: (2018-12-01)
by: André Kleinridders, et al.
Published: (2018-12-01)
Mitochondria, Oxidative Stress, cAMP Signalling and Apoptosis: A Crossroads in Lymphocytes of Multiple Sclerosis, a Possible Role of Nutraceutics
by: Anna Signorile, et al.
Published: (2020-12-01)
by: Anna Signorile, et al.
Published: (2020-12-01)
Characteristics of stachyose-induced effects on gut microbiota and microbial metabolites in vitro associated with obesity in children
by: Xionge Pi, et al.
Published: (2024-08-01)
by: Xionge Pi, et al.
Published: (2024-08-01)
Mitochondrial Dysfunction and Multiple Sclerosis
by: Isabella Peixoto de Barcelos, et al.
Published: (2019-05-01)
by: Isabella Peixoto de Barcelos, et al.
Published: (2019-05-01)
Early Synapse-Specific Alterations of Photoreceptor Mitochondria in the EAE Mouse Model of Multiple Sclerosis
by: Dalia R. Ibrahim, et al.
Published: (2025-01-01)
by: Dalia R. Ibrahim, et al.
Published: (2025-01-01)
Mitochondria: A Promising Convergent Target for the Treatment of Amyotrophic Lateral Sclerosis
by: Teresa Cunha-Oliveira, et al.
Published: (2024-01-01)
by: Teresa Cunha-Oliveira, et al.
Published: (2024-01-01)
New targets for the treatment of ulcerative colitis: Gut microbiota and its metabolites
by: Huanyu Li, et al.
Published: (2025-01-01)
by: Huanyu Li, et al.
Published: (2025-01-01)
The role of mitochondria-endoplasmic reticulum crosstalk in colorectal cancer
by: Lanshu Xiao, et al.
Published: (2026-01-01)
by: Lanshu Xiao, et al.
Published: (2026-01-01)
Untargeted metabonomic analysis of a cerebral stroke model in rats: a study based on UPLC–MS/MS
by: Dunbing Huang, et al.
Published: (2023-08-01)
by: Dunbing Huang, et al.
Published: (2023-08-01)
The ER mitochondria calcium cycle and ER stress response as therapeutic targets in amyotrophic lateral sclerosis
by: Vedrana eTadic, et al.
Published: (2014-05-01)
by: Vedrana eTadic, et al.
Published: (2014-05-01)
Investigating the metabolite signature of an altered oral microbiota as a discriminant factor for multiple sclerosis: a pilot study
by: Léo Boussamet, et al.
Published: (2024-04-01)
by: Léo Boussamet, et al.
Published: (2024-04-01)
Dysfunctional Mitochondria Characterize Amyotrophic Lateral Sclerosis Patients’ Cells Carrying the p.G376D <i>TARDBP</i> Pathogenetic Substitution
by: Giuseppe Petito, et al.
Published: (2025-03-01)
by: Giuseppe Petito, et al.
Published: (2025-03-01)
In vivo systematic analysis of microbiota-prebiotic crosstalk reveals a synbiotic that effectively ameliorates DSS-induced colitis in mice
by: Qianwen Peng, et al.
Published: (2025-12-01)
by: Qianwen Peng, et al.
Published: (2025-12-01)
Schizophrenia and obesity: May the gut microbiota serve as a link for the pathogenesis?
by: Hui Wu, et al.
Published: (2023-05-01)
by: Hui Wu, et al.
Published: (2023-05-01)
Mitochondria in Alzheimer’s Disease Pathogenesis
by: Allison B. Reiss, et al.
Published: (2024-01-01)
by: Allison B. Reiss, et al.
Published: (2024-01-01)
Betaine restores epigenetic control and supports neuronal mitochondria in the cuprizone mouse model of multiple sclerosis
by: Naveen K. Singhal, et al.
Published: (2020-08-01)
by: Naveen K. Singhal, et al.
Published: (2020-08-01)
The role of intestinal microbiota in the development of dyslipidemia and cardiovascular disease risk
by: T. V. Bogoslav
Published: (2024-04-01)
by: T. V. Bogoslav
Published: (2024-04-01)
Estrogen Degradation Metabolites: Some Effects on Heart Mitochondria
by: Cristina Uribe-Alvarez, et al.
Published: (2025-10-01)
by: Cristina Uribe-Alvarez, et al.
Published: (2025-10-01)
Endoplasmic reticulum-mitochondria crosstalk: new mechanisms in the development of atherosclerosis
by: Mingxiao Li, et al.
Published: (2025-06-01)
by: Mingxiao Li, et al.
Published: (2025-06-01)
Modulation of gut microbiota, blood metabolites, and disease resistance by dietary β-glucan in rainbow trout (Oncorhynchus mykiss)
by: Simon Menanteau-Ledouble, et al.
Published: (2022-11-01)
by: Simon Menanteau-Ledouble, et al.
Published: (2022-11-01)
Gait variability and biomechanical distinctions in individuals with functional ankle instability: a case–control study based on three-dimensional motion analysis
by: Dunbing Huang, et al.
Published: (2025-06-01)
by: Dunbing Huang, et al.
Published: (2025-06-01)
The role of mitochondria in the pathogenesis of the "complex" wound process
by: A. A. Supilnikov, et al.
Published: (2022-11-01)
by: A. A. Supilnikov, et al.
Published: (2022-11-01)
Modulating the Gut Microbiota with Alginate Oligosaccharides In Vitro
by: Grégoire Bouillon, et al.
Published: (2022-12-01)
by: Grégoire Bouillon, et al.
Published: (2022-12-01)
Sending out an SOS: Mitochondria as a signaling hub
by: Iryna Bohovych, et al.
Published: (2016-10-01)
by: Iryna Bohovych, et al.
Published: (2016-10-01)
Crosstalk between Mitochondria and Cytoskeleton in Cardiac Cells
by: Andrey V. Kuznetsov, et al.
Published: (2020-01-01)
by: Andrey V. Kuznetsov, et al.
Published: (2020-01-01)
Central Nervous System Proteomics in Animal Model of Multiple Sclerosis Revealed Down-Regulation of Mithochondrial Proteins
by: Abolhassan Shahzadeh Fazeli, et al.
Published: (2009-01-01)
by: Abolhassan Shahzadeh Fazeli, et al.
Published: (2009-01-01)
Crosstalk between glucagon-like peptide 1 and gut microbiota in metabolic diseases
by: Yuan Zeng, et al.
Published: (2024-01-01)
by: Yuan Zeng, et al.
Published: (2024-01-01)
The Impact of Microbiota on the Pathogenesis of Amyotrophic Lateral Sclerosis and the Possible Benefits of Polyphenols. An Overview
by: Julia Casani-Cubel, et al.
Published: (2021-02-01)
by: Julia Casani-Cubel, et al.
Published: (2021-02-01)
Editorial: Role of probiotics and probiotics' metabolites in food and intestine
by: Vincenzina Fusco, et al.
Published: (2023-03-01)
by: Vincenzina Fusco, et al.
Published: (2023-03-01)
The role of gut microbiota dysbiosis in the inflammatory pathogenesis of diabetic retinopathy
by: Liqing Xie, et al.
Published: (2025-07-01)
by: Liqing Xie, et al.
Published: (2025-07-01)
Similar Items
-
The Crosstalk between the Gut Microbiota and Mitochondria during Exercise
by: Allison Clark, et al.
Published: (2017-05-01) -
The complexities of investigating mitochondria dynamics in multiple sclerosis and mouse models of MS
by: Kelley C. Atkinson, et al.
Published: (2023-07-01) -
Understanding the Holobiont: Crosstalk Between Gut Microbiota and Mitochondria During Long Exercise in Horse
by: Núria Mach, et al.
Published: (2021-04-01) -
Gut microbiota: a novel strategy affecting atherosclerosis
by: Lingshuang Yang, et al.
Published: (2025-08-01) -
Amyotrophic Lateral Sclerosis (ALS): Stressed by Dysfunctional Mitochondria-Endoplasmic Reticulum Contacts (MERCs)
by: Junsheng Chen, et al.
Published: (2021-07-01)
